5 Questions
Which route of drug administration refers to applying topically to the mouth or swallowing for absorption along the gastrointestinal (GI) tract into systemic circulation?
Oral
What is the abbreviation used to indicate the oral route of medication administration?
po
Which of the following is an advantage of the oral route of drug administration?
Convenient and easy to take
What is meant by 'first-pass effect' in relation to the oral route of drug administration?
Drugs absorbed orally are initially transported to the liver via the portal vein
What is a significant disadvantage of the oral route of drug administration?
Slow onset, not suitable for emergencies
Study Notes
Oral Route of Drug Administration
- The oral route of drug administration involves applying the drug topically to the mouth or swallowing it for absorption along the gastrointestinal (GI) tract into systemic circulation.
- The abbreviation used to indicate the oral route of medication administration is PO.
Advantages of Oral Route
- One advantage of the oral route is that it is convenient and easy to use, especially for patients who require long-term treatment.
First-Pass Effect
- The 'first-pass effect' refers to the process by which the liver metabolizes a significant portion of the drug before it reaches the systemic circulation, reducing the bioavailability of the drug.
Disadvantages of Oral Route
- A significant disadvantage of the oral route is that it can result in unpredictable drug absorption due to variations in gastric emptying time, pH, and the presence of food or other substances in the GI tract.
Test your knowledge of the different channels of drug administration and their effects on drug action speed and efficiency. This quiz covers important information about enteral, parenteral, inhalation, and topical routes of drug administration.
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