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Questions and Answers
What is the main advantage of the oral route of administration?
What is the main advantage of the oral route of administration?
- Easy, safe, and convenient (correct)
- Rapid absorption of drugs (correct)
- Suitable for uncooperative or unconscious patients
- Prevents first-pass effect
What is the limitation of the oral route of administration?
What is the limitation of the oral route of administration?
- It is not convenient (correct)
- It is not preferred by patients
- Limited absorption of some drugs
- It is not economical
What is the benefit of slow-release preparations in the oral route?
What is the benefit of slow-release preparations in the oral route?
- Protection from digestive enzymes and acid (correct)
- Reduced toxicity
- Suitable for uncooperative patients
- Faster absorption of drugs
What is the consequence of the first-pass effect in the oral route?
What is the consequence of the first-pass effect in the oral route?
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What is an alternative to the oral route when it is not suitable?
What is an alternative to the oral route when it is not suitable?
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Study Notes
Classification of Routes of Drug Administration
- Classified based on the target of action into:
- Enteral (systemic action, but delivered through the gastrointestinal tract)
- Parenteral (systemic action, but delivered by routes other than the GI tract)
- Topical (local) and other routes
Enteral Routes of Drug Administration
- Includes:
- Oral
- Sublingual
- Buccal
- Rectal
Oral Route of Administration
- Advantages:
- Easy to administer
- Safe
- Most common route
- Convenient
- Economical
- Preferred by patients
- Slow-release preparations available to extend duration of action
- Time availability to reverse toxicity
- Disadvantages:
- Limited absorption of some drugs
- Food may affect absorption
- Unsuitable for uncooperative or unconscious patients
- Drugs may be metabolized before systemic absorption (First-pass effect)
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