Routes of Drug Administration

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5 Questions

What is the main advantage of the oral route of administration?

Easy, safe, and convenient

What is the limitation of the oral route of administration?

It is not convenient

What is the benefit of slow-release preparations in the oral route?

Protection from digestive enzymes and acid

What is the consequence of the first-pass effect in the oral route?

Drugs are metabolized before systemic absorption

What is an alternative to the oral route when it is not suitable?

Parenteral route

Study Notes

Classification of Routes of Drug Administration

  • Classified based on the target of action into:
    • Enteral (systemic action, but delivered through the gastrointestinal tract)
    • Parenteral (systemic action, but delivered by routes other than the GI tract)
    • Topical (local) and other routes

Enteral Routes of Drug Administration

  • Includes:
    • Oral
    • Sublingual
    • Buccal
    • Rectal

Oral Route of Administration

  • Advantages:
    • Easy to administer
    • Safe
    • Most common route
    • Convenient
    • Economical
    • Preferred by patients
    • Slow-release preparations available to extend duration of action
    • Time availability to reverse toxicity
  • Disadvantages:
    • Limited absorption of some drugs
    • Food may affect absorption
    • Unsuitable for uncooperative or unconscious patients
    • Drugs may be metabolized before systemic absorption (First-pass effect)

This quiz covers the different routes of drug administration, including enteral, parenteral, topical, and other routes. Learn about the advantages and disadvantages of each route and how they work.

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