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WK 8: Intro to Pharmacokinetics

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30 Questions

Which route of administration allows drugs to bypass first-pass metabolism?

Sublingual

Which formulation can be used for oral administration?

Enteric-coated tablets

Which age group may have reduced renal and liver function affecting drug elimination?

Elderly people

Which condition may impact the absorption, distribution, metabolism, and elimination of drugs?

Stomach ulcers

Which route of administration involves direct application on skin and mucosal surfaces?

Topical

For which type of drug could sublingual administration be ideal?

Lipophilic drugs

Which characteristic makes oral administration the most commonly used route?

Ease and convenience

Which age group might have incomplete development of renal elimination?

Infants

Which route of administration involves injections into fatty tissue?

Intramuscular

Which disease might affect drug metabolism leading to altered drug levels in the body?

Liver cancer

What is the primary route of administration for oral medications?

Through the mouth

Which route of administration bypasses the first-pass effect?

Parenteral administration

What is the advantage of sublingual administration?

It produces a rapid onset of action

Which route of administration is used for localized effects?

Topical administration

What is the primary advantage of parenteral administration?

It produces a rapid onset of action

Which route of administration involves injecting a drug into a muscle?

Intramuscular administration

What is the primary disadvantage of oral administration?

It is susceptible to the first-pass effect

Which route of administration involves injecting a drug under the skin?

Subcutaneous administration

What is the primary advantage of topical administration?

It allows for localized effects

Which route of administration involves injecting a drug into a vein?

Intravenous administration

What is the primary advantage of parenteral administration over oral administration?

Avoids potential problems with absorption

Which route of administration involves the use of nasal sprays to deliver antidiuretic hormone?

Local administration

What determines the rate of diffusion of drugs across the GI tract?

Molecular weight and lipid solubility

What is the primary mechanism of drug absorption across the GI lining?

Passive diffusion

Which of the following is an example of topical administration?

Transdermal application

What is the term for the movement of drugs through the cellular barriers of the GI lining?

Diffusion

What is the purpose of protein binding in the bloodstream?

To facilitate drug distribution

What is the term for the process by which drugs cross the GI lining?

Absorption

What is the term for the administration of drugs through the skin using patches?

Transdermal administration

What is the primary characteristic of drugs that are highly bound to plasma proteins?

They are poorly absorbed

Learn about the different routes of administration in pharmacology, including oral, topical, and parenteral methods. Understand how different medications are delivered through drops, sprays, injections, and infusions for local and systemic effects.

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