WK 8: Intro to Pharmacokinetics

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Which route of administration allows drugs to bypass first-pass metabolism?

Sublingual (correct)

Intramuscular

Topical

Oral

Which formulation can be used for oral administration?

IV injection

Intranasal spray

Enteric-coated tablets (correct)

Transdermal patch

Which age group may have reduced renal and liver function affecting drug elimination?

Teenagers

Young adults

Infants

Elderly people (correct)

Which condition may impact the absorption, distribution, metabolism, and elimination of drugs?

Stomach ulcers Signup and view all the answers

Which route of administration involves direct application on skin and mucosal surfaces?

Topical Signup and view all the answers

For which type of drug could sublingual administration be ideal?

Lipophilic drugs Signup and view all the answers

Which characteristic makes oral administration the most commonly used route?

Ease and convenience Signup and view all the answers

Which age group might have incomplete development of renal elimination?

Infants Signup and view all the answers

Which route of administration involves injections into fatty tissue?

Intramuscular Signup and view all the answers

Which disease might affect drug metabolism leading to altered drug levels in the body?

Liver cancer Signup and view all the answers

What is the primary route of administration for oral medications?

Through the mouth Signup and view all the answers

Which route of administration bypasses the first-pass effect?

Parenteral administration Signup and view all the answers

What is the advantage of sublingual administration?

It produces a rapid onset of action Signup and view all the answers

Which route of administration is used for localized effects?

Topical administration Signup and view all the answers

What is the primary advantage of parenteral administration?

It produces a rapid onset of action Signup and view all the answers

Which route of administration involves injecting a drug into a muscle?

Intramuscular administration Signup and view all the answers

What is the primary disadvantage of oral administration?

It is susceptible to the first-pass effect Signup and view all the answers

Which route of administration involves injecting a drug under the skin?

Subcutaneous administration Signup and view all the answers

What is the primary advantage of topical administration?

It allows for localized effects Signup and view all the answers

Which route of administration involves injecting a drug into a vein?

Intravenous administration Signup and view all the answers

What is the primary advantage of parenteral administration over oral administration?

Avoids potential problems with absorption Signup and view all the answers

Which route of administration involves the use of nasal sprays to deliver antidiuretic hormone?

Local administration Signup and view all the answers

What determines the rate of diffusion of drugs across the GI tract?

Molecular weight and lipid solubility Signup and view all the answers

What is the primary mechanism of drug absorption across the GI lining?

Passive diffusion Signup and view all the answers

Which of the following is an example of topical administration?

Transdermal application Signup and view all the answers

What is the term for the movement of drugs through the cellular barriers of the GI lining?

Diffusion Signup and view all the answers

What is the purpose of protein binding in the bloodstream?

To facilitate drug distribution Signup and view all the answers

What is the term for the process by which drugs cross the GI lining?

Absorption Signup and view all the answers

What is the term for the administration of drugs through the skin using patches?

Transdermal administration Signup and view all the answers

What is the primary characteristic of drugs that are highly bound to plasma proteins?

They are poorly absorbed Signup and view all the answers