WK 8: Intro to Pharmacokinetics
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Questions and Answers

Which route of administration allows drugs to bypass first-pass metabolism?

  • Sublingual (correct)
  • Intramuscular
  • Topical
  • Oral

Which formulation can be used for oral administration?

  • IV injection
  • Intranasal spray
  • Enteric-coated tablets (correct)
  • Transdermal patch

Which age group may have reduced renal and liver function affecting drug elimination?

  • Teenagers
  • Young adults
  • Infants
  • Elderly people (correct)

Which condition may impact the absorption, distribution, metabolism, and elimination of drugs?

<p>Stomach ulcers (A)</p> Signup and view all the answers

Which route of administration involves direct application on skin and mucosal surfaces?

<p>Topical (D)</p> Signup and view all the answers

For which type of drug could sublingual administration be ideal?

<p>Lipophilic drugs (D)</p> Signup and view all the answers

Which characteristic makes oral administration the most commonly used route?

<p>Ease and convenience (C)</p> Signup and view all the answers

Which age group might have incomplete development of renal elimination?

<p>Infants (D)</p> Signup and view all the answers

Which route of administration involves injections into fatty tissue?

<p>Intramuscular (D)</p> Signup and view all the answers

Which disease might affect drug metabolism leading to altered drug levels in the body?

<p>Liver cancer (A)</p> Signup and view all the answers

What is the primary route of administration for oral medications?

<p>Through the mouth (B)</p> Signup and view all the answers

Which route of administration bypasses the first-pass effect?

<p>Parenteral administration (C)</p> Signup and view all the answers

What is the advantage of sublingual administration?

<p>It produces a rapid onset of action (B)</p> Signup and view all the answers

Which route of administration is used for localized effects?

<p>Topical administration (D)</p> Signup and view all the answers

What is the primary advantage of parenteral administration?

<p>It produces a rapid onset of action (A)</p> Signup and view all the answers

Which route of administration involves injecting a drug into a muscle?

<p>Intramuscular administration (A)</p> Signup and view all the answers

What is the primary disadvantage of oral administration?

<p>It is susceptible to the first-pass effect (B)</p> Signup and view all the answers

Which route of administration involves injecting a drug under the skin?

<p>Subcutaneous administration (B)</p> Signup and view all the answers

What is the primary advantage of topical administration?

<p>It allows for localized effects (A)</p> Signup and view all the answers

Which route of administration involves injecting a drug into a vein?

<p>Intravenous administration (A)</p> Signup and view all the answers

What is the primary advantage of parenteral administration over oral administration?

<p>Avoids potential problems with absorption (A)</p> Signup and view all the answers

Which route of administration involves the use of nasal sprays to deliver antidiuretic hormone?

<p>Local administration (D)</p> Signup and view all the answers

What determines the rate of diffusion of drugs across the GI tract?

<p>Molecular weight and lipid solubility (B)</p> Signup and view all the answers

What is the primary mechanism of drug absorption across the GI lining?

<p>Passive diffusion (B)</p> Signup and view all the answers

Which of the following is an example of topical administration?

<p>Transdermal application (D)</p> Signup and view all the answers

What is the term for the movement of drugs through the cellular barriers of the GI lining?

<p>Diffusion (C)</p> Signup and view all the answers

What is the purpose of protein binding in the bloodstream?

<p>To facilitate drug distribution (A)</p> Signup and view all the answers

What is the term for the process by which drugs cross the GI lining?

<p>Absorption (A)</p> Signup and view all the answers

What is the term for the administration of drugs through the skin using patches?

<p>Transdermal administration (A)</p> Signup and view all the answers

What is the primary characteristic of drugs that are highly bound to plasma proteins?

<p>They are poorly absorbed (A)</p> Signup and view all the answers

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