WK 8: Intro to Pharmacokinetics
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Questions and Answers

Which route of administration allows drugs to bypass first-pass metabolism?

  • Sublingual (correct)
  • Intramuscular
  • Topical
  • Oral
  • Which formulation can be used for oral administration?

  • IV injection
  • Intranasal spray
  • Enteric-coated tablets (correct)
  • Transdermal patch
  • Which age group may have reduced renal and liver function affecting drug elimination?

  • Teenagers
  • Young adults
  • Infants
  • Elderly people (correct)
  • Which condition may impact the absorption, distribution, metabolism, and elimination of drugs?

    <p>Stomach ulcers</p> Signup and view all the answers

    Which route of administration involves direct application on skin and mucosal surfaces?

    <p>Topical</p> Signup and view all the answers

    For which type of drug could sublingual administration be ideal?

    <p>Lipophilic drugs</p> Signup and view all the answers

    Which characteristic makes oral administration the most commonly used route?

    <p>Ease and convenience</p> Signup and view all the answers

    Which age group might have incomplete development of renal elimination?

    <p>Infants</p> Signup and view all the answers

    Which route of administration involves injections into fatty tissue?

    <p>Intramuscular</p> Signup and view all the answers

    Which disease might affect drug metabolism leading to altered drug levels in the body?

    <p>Liver cancer</p> Signup and view all the answers

    What is the primary route of administration for oral medications?

    <p>Through the mouth</p> Signup and view all the answers

    Which route of administration bypasses the first-pass effect?

    <p>Parenteral administration</p> Signup and view all the answers

    What is the advantage of sublingual administration?

    <p>It produces a rapid onset of action</p> Signup and view all the answers

    Which route of administration is used for localized effects?

    <p>Topical administration</p> Signup and view all the answers

    What is the primary advantage of parenteral administration?

    <p>It produces a rapid onset of action</p> Signup and view all the answers

    Which route of administration involves injecting a drug into a muscle?

    <p>Intramuscular administration</p> Signup and view all the answers

    What is the primary disadvantage of oral administration?

    <p>It is susceptible to the first-pass effect</p> Signup and view all the answers

    Which route of administration involves injecting a drug under the skin?

    <p>Subcutaneous administration</p> Signup and view all the answers

    What is the primary advantage of topical administration?

    <p>It allows for localized effects</p> Signup and view all the answers

    Which route of administration involves injecting a drug into a vein?

    <p>Intravenous administration</p> Signup and view all the answers

    What is the primary advantage of parenteral administration over oral administration?

    <p>Avoids potential problems with absorption</p> Signup and view all the answers

    Which route of administration involves the use of nasal sprays to deliver antidiuretic hormone?

    <p>Local administration</p> Signup and view all the answers

    What determines the rate of diffusion of drugs across the GI tract?

    <p>Molecular weight and lipid solubility</p> Signup and view all the answers

    What is the primary mechanism of drug absorption across the GI lining?

    <p>Passive diffusion</p> Signup and view all the answers

    Which of the following is an example of topical administration?

    <p>Transdermal application</p> Signup and view all the answers

    What is the term for the movement of drugs through the cellular barriers of the GI lining?

    <p>Diffusion</p> Signup and view all the answers

    What is the purpose of protein binding in the bloodstream?

    <p>To facilitate drug distribution</p> Signup and view all the answers

    What is the term for the process by which drugs cross the GI lining?

    <p>Absorption</p> Signup and view all the answers

    What is the term for the administration of drugs through the skin using patches?

    <p>Transdermal administration</p> Signup and view all the answers

    What is the primary characteristic of drugs that are highly bound to plasma proteins?

    <p>They are poorly absorbed</p> Signup and view all the answers

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