Podcast
Questions and Answers
What is the purpose of using horse immunoglobulin ATGAM® in renal transplant patients?
What is the purpose of using horse immunoglobulin ATGAM® in renal transplant patients?
What is the most serious reaction that could occur with animal immunoglobulin therapy?
What is the most serious reaction that could occur with animal immunoglobulin therapy?
How should infusion be managed if anaphylaxis occurs during animal immunoglobulin therapy?
How should infusion be managed if anaphylaxis occurs during animal immunoglobulin therapy?
Which antibody is used to remove cytotoxic T cells responsible for graft rejection in kidney transplantation?
Which antibody is used to remove cytotoxic T cells responsible for graft rejection in kidney transplantation?
Signup and view all the answers
What is the recommended action before treating a patient with specific animal immunoglobulins like horse immunoglobulin ATGAM®?
What is the recommended action before treating a patient with specific animal immunoglobulins like horse immunoglobulin ATGAM®?
Signup and view all the answers
What should be done if other reactions like chills, fever, itching, and erythema occur during animal immunoglobulin therapy?
What should be done if other reactions like chills, fever, itching, and erythema occur during animal immunoglobulin therapy?
Signup and view all the answers
What is the primary source of human immunoglobulins used as drugs?
What is the primary source of human immunoglobulins used as drugs?
Signup and view all the answers
Which of the following is NOT a correct application of human immunoglobulins obtained from the general population?
Which of the following is NOT a correct application of human immunoglobulins obtained from the general population?
Signup and view all the answers
What is the typical route of administration for human immunoglobulin solutions obtained from healthy donors?
What is the typical route of administration for human immunoglobulin solutions obtained from healthy donors?
Signup and view all the answers
What is the approximate half-life of intravenous immunoglobulin solutions in the patient's blood?
What is the approximate half-life of intravenous immunoglobulin solutions in the patient's blood?
Signup and view all the answers
Which type of human immunoglobulin solutions are specifically used for postexposure prophylaxis or preventive treatment before hepatitis B vaccination?
Which type of human immunoglobulin solutions are specifically used for postexposure prophylaxis or preventive treatment before hepatitis B vaccination?
Signup and view all the answers
What is the term used for the use of human immunoglobulin solutions for the prevention of either general or specific infections?
What is the term used for the use of human immunoglobulin solutions for the prevention of either general or specific infections?
Signup and view all the answers
What percentage of rejection can be reversed with OKT3® treatment compared to conventional immunosuppressive treatment?
What percentage of rejection can be reversed with OKT3® treatment compared to conventional immunosuppressive treatment?
Signup and view all the answers
In which type of transplantation are anti-T cell monoclonal antibodies used as an ex vivo treatment?
In which type of transplantation are anti-T cell monoclonal antibodies used as an ex vivo treatment?
Signup and view all the answers
What is the purpose of using anti-T cell monoclonal antibodies in heterologous transplantations?
What is the purpose of using anti-T cell monoclonal antibodies in heterologous transplantations?
Signup and view all the answers
What is one of the most common reactions in using monoclonal antibodies for the treatment of human diseases?
What is one of the most common reactions in using monoclonal antibodies for the treatment of human diseases?
Signup and view all the answers
When does the reaction of developing HAMA usually occur after the initial treatment with monoclonal antibodies?
When does the reaction of developing HAMA usually occur after the initial treatment with monoclonal antibodies?
Signup and view all the answers
What are the two technologies currently being developed to minimize the problems associated with the formation of HAMA in monoclonal antibody-treated patients?
What are the two technologies currently being developed to minimize the problems associated with the formation of HAMA in monoclonal antibody-treated patients?
Signup and view all the answers