Rotavirus Infections and Genome Structure
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Questions and Answers

What defines the G serotypes of rotavirus?

  • Secretory IgA
  • VP7 glycoprotein (correct)
  • VP4 protease-sensitive protein
  • VP6 protein

Which protein defines the P serotypes of rotavirus?

  • VP4 protease-sensitive protein (correct)
  • VP6 protein
  • Secretory IgA
  • VP7 glycoprotein

What is important for protection against rotavirus?

  • VP7 glycoprotein
  • VP6 protein
  • Secretory IgA (correct)
  • VP4 protease-sensitive protein

At what age do most symptomatic rotavirus infections occur?

<p>Between 3 months and 2 years old (C)</p> Signup and view all the answers

What is the most common route of rotavirus infection transmission?

<p>Contact with contaminated hands, surfaces, and objects (A)</p> Signup and view all the answers

Which method is the most sensitive for detecting Rotavirus Nucleic Acid from stool specimens?

<p>PCR/Genotyping (C)</p> Signup and view all the answers

Which protein of rotavirus is responsible for binding to host cell receptors?

<p>VP4 (A)</p> Signup and view all the answers

How many structural viral proteins are there in rotavirus?

<p>Six (C)</p> Signup and view all the answers

What is the role of VP6 in rotavirus?

<p>Highly antigenic protein that identifies rotavirus species (B)</p> Signup and view all the answers

What is the function of VP7 in rotavirus?

<p>Forms outer surface of the virion, induces neutralizing antibodies (B)</p> Signup and view all the answers

Which enzyme cleaves VP4 into VP5* and VP8* in the gut?

<p>Protease (C)</p> Signup and view all the answers

Genetic re-assortment in rotavirus occurs due to:

<p>High frequency during co-infection (D)</p> Signup and view all the answers

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