Rotavirus Infections and Genome Structure
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Questions and Answers

What defines the G serotypes of rotavirus?

  • Secretory IgA
  • VP7 glycoprotein (correct)
  • VP4 protease-sensitive protein
  • VP6 protein
  • Which protein defines the P serotypes of rotavirus?

  • VP4 protease-sensitive protein (correct)
  • VP6 protein
  • Secretory IgA
  • VP7 glycoprotein
  • What is important for protection against rotavirus?

  • VP7 glycoprotein
  • VP6 protein
  • Secretory IgA (correct)
  • VP4 protease-sensitive protein
  • At what age do most symptomatic rotavirus infections occur?

    <p>Between 3 months and 2 years old</p> Signup and view all the answers

    What is the most common route of rotavirus infection transmission?

    <p>Contact with contaminated hands, surfaces, and objects</p> Signup and view all the answers

    Which method is the most sensitive for detecting Rotavirus Nucleic Acid from stool specimens?

    <p>PCR/Genotyping</p> Signup and view all the answers

    Which protein of rotavirus is responsible for binding to host cell receptors?

    <p>VP4</p> Signup and view all the answers

    How many structural viral proteins are there in rotavirus?

    <p>Six</p> Signup and view all the answers

    What is the role of VP6 in rotavirus?

    <p>Highly antigenic protein that identifies rotavirus species</p> Signup and view all the answers

    What is the function of VP7 in rotavirus?

    <p>Forms outer surface of the virion, induces neutralizing antibodies</p> Signup and view all the answers

    Which enzyme cleaves VP4 into VP5* and VP8* in the gut?

    <p>Protease</p> Signup and view all the answers

    Genetic re-assortment in rotavirus occurs due to:

    <p>High frequency during co-infection</p> Signup and view all the answers

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