Role of Serum Amyloid A, Mannose Binding Protein, and Alpha1-Antitrypsin in Infections
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Questions and Answers

What is the primary function of Haptoglobin?

  • Removing cholesterol from macrophages
  • Preventing bacterial infections
  • Binding irreversibly to free hemoglobin (correct)
  • Facilitating clot formation

Which protein contributes to the cleaning up of tissue injury by removing cholesterol from cholesterol-filled macrophages?

  • Serum Amyloid A (correct)
  • Fibrinogen
  • Mannose Binding Protein
  • Alpha1-Antitrypsin

What is the consequence of Alpha1-Antitrypsin deficiency?

  • Increased risk of premature emphysema (correct)
  • Protection against tissue injury
  • Enhanced immune response
  • Improved blood clotting

What does Mannose Binding Protein act as?

<p>An opsonin (C)</p> Signup and view all the answers

Which protein is the most abundant coagulation factor in plasma?

<p>Fibrinogen (B)</p> Signup and view all the answers

What is the main role of Ceruloplasmin in human plasma?

<p>Transporting copper (B)</p> Signup and view all the answers

What leads to the rise in plasma Haptoglobin levels?

<p>De novo synthesis by the liver (D)</p> Signup and view all the answers

'Lack of MBP has been associated with recurrent yeast infections.' Which protein is being referred to as MBP?

<p>Mannose Binding Protein (B)</p> Signup and view all the answers

In which condition can Haptoglobin play an important role in protecting the kidney?

<p>Wilson’s disease (B)</p> Signup and view all the answers

What is the main function of azurophilic granules in neutrophils?

<p>Contain primary, secondary, and tertiary granules (D)</p> Signup and view all the answers

Which cell type is responsible for maintaining immediate hypersensitivity reactions?

<p>Basophils (C)</p> Signup and view all the answers

What distinguishes eosinophils from neutrophils in terms of phagocytosis efficiency?

<p>Higher numbers present (D)</p> Signup and view all the answers

Which cell type becomes a macrophage when it moves from blood vessels to tissues?

<p>Monocytes (D)</p> Signup and view all the answers

What is the most significant difference between basophils and mast cells?

<p>Granule content (D)</p> Signup and view all the answers

Why are lymphocytes unable to perform chemotaxis and diapedesis?

<p>They lack the necessary receptors for chemotaxis. (B)</p> Signup and view all the answers

Which of the following is NOT a type of lymphocyte?

<p>R lymphocyte (B)</p> Signup and view all the answers

Where do B lymphocytes mature?

<p>Bone marrow (B)</p> Signup and view all the answers

Which organ is responsible for the antigen-independent production of lymphocytes?

<p>Bone marrow (B)</p> Signup and view all the answers

What is the main distinguishing feature of lymphocytes in terms of their life span?

<p>They die within a few days if not activated by foreign antigens. (C)</p> Signup and view all the answers

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