Role of Serum Amyloid A, Mannose Binding Protein, and Alpha1-Antitrypsin in Infections

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19 Questions

What is the primary function of Haptoglobin?

Binding irreversibly to free hemoglobin

Which protein contributes to the cleaning up of tissue injury by removing cholesterol from cholesterol-filled macrophages?

Serum Amyloid A

What is the consequence of Alpha1-Antitrypsin deficiency?

Increased risk of premature emphysema

What does Mannose Binding Protein act as?

An opsonin

Which protein is the most abundant coagulation factor in plasma?

Fibrinogen

What is the main role of Ceruloplasmin in human plasma?

Transporting copper

What leads to the rise in plasma Haptoglobin levels?

De novo synthesis by the liver

'Lack of MBP has been associated with recurrent yeast infections.' Which protein is being referred to as MBP?

Mannose Binding Protein

In which condition can Haptoglobin play an important role in protecting the kidney?

Wilson’s disease

What is the main function of azurophilic granules in neutrophils?

Contain primary, secondary, and tertiary granules

Which cell type is responsible for maintaining immediate hypersensitivity reactions?

Basophils

What distinguishes eosinophils from neutrophils in terms of phagocytosis efficiency?

Higher numbers present

Which cell type becomes a macrophage when it moves from blood vessels to tissues?

Monocytes

What is the most significant difference between basophils and mast cells?

Granule content

Why are lymphocytes unable to perform chemotaxis and diapedesis?

They lack the necessary receptors for chemotaxis.

Which of the following is NOT a type of lymphocyte?

R lymphocyte

Where do B lymphocytes mature?

Bone marrow

Which organ is responsible for the antigen-independent production of lymphocytes?

Bone marrow

What is the main distinguishing feature of lymphocytes in terms of their life span?

They die within a few days if not activated by foreign antigens.

Explore the functions of Serum Amyloid A, Mannose Binding Protein, and Alpha1-Antitrypsin in the immune response. Learn how these proteins contribute to infection control and tissue repair.

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