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Role of Serum Amyloid A, Mannose Binding Protein, and Alpha1-Antitrypsin in Infections

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Role of Serum Amyloid A, Mannose Binding Protein, and Alpha1-Antitrypsin in Infections

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Questions and Answers

What is the primary function of Haptoglobin?

Removing cholesterol from macrophages

Preventing bacterial infections

Binding irreversibly to free hemoglobin (correct)

Facilitating clot formation

Which protein contributes to the cleaning up of tissue injury by removing cholesterol from cholesterol-filled macrophages?

Serum Amyloid A (correct)

Fibrinogen

Mannose Binding Protein

Alpha1-Antitrypsin

What is the consequence of Alpha1-Antitrypsin deficiency?

Increased risk of premature emphysema (correct)

Protection against tissue injury

Enhanced immune response

Improved blood clotting

What does Mannose Binding Protein act as?

An opsonin (C) Signup and view all the answers

Which protein is the most abundant coagulation factor in plasma?

Fibrinogen (B) Signup and view all the answers

What is the main role of Ceruloplasmin in human plasma?

Transporting copper (B) Signup and view all the answers

What leads to the rise in plasma Haptoglobin levels?

De novo synthesis by the liver (D) Signup and view all the answers

'Lack of MBP has been associated with recurrent yeast infections.' Which protein is being referred to as MBP?

Mannose Binding Protein (B) Signup and view all the answers

In which condition can Haptoglobin play an important role in protecting the kidney?

Wilson’s disease (B) Signup and view all the answers

What is the main function of azurophilic granules in neutrophils?

Contain primary, secondary, and tertiary granules (D) Signup and view all the answers

Which cell type is responsible for maintaining immediate hypersensitivity reactions?

Basophils (C) Signup and view all the answers

What distinguishes eosinophils from neutrophils in terms of phagocytosis efficiency?

Higher numbers present (D) Signup and view all the answers

Which cell type becomes a macrophage when it moves from blood vessels to tissues?

Monocytes (D) Signup and view all the answers

What is the most significant difference between basophils and mast cells?

Granule content (D) Signup and view all the answers

Why are lymphocytes unable to perform chemotaxis and diapedesis?

They lack the necessary receptors for chemotaxis. (B) Signup and view all the answers

Which of the following is NOT a type of lymphocyte?

R lymphocyte (B) Signup and view all the answers

Where do B lymphocytes mature?

Bone marrow (B) Signup and view all the answers

Which organ is responsible for the antigen-independent production of lymphocytes?