Transcription

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Which RNA polymerase is responsible for transcribing rRNA?

Pol II
Pol I (correct)
Pol III
All of the above

What is the function of the TBP protein in transcription initiation?

It binds to BRE and helps with kinking
It binds to INR and inhibits transcription
It binds to DPE and recruits Pol II
It binds to TATA box and kinks DNA (correct)

What is the role of the C-terminal domain in transcription?

It binds to the tail of Pol II and gets phosphorylated (correct)
It helps with chromatin remodeling
It inhibits Pol II recruitment
It is involved in RNA degradation

What is the function of the capping machinery during transcription?

It removes the 5'-triphosphate from the nascent RNA (B) Signup and view all the answers

What is the role of the poly(A)-binding proteins (PABAs) in mRNA stability?

They help stabilize mRNA (C) Signup and view all the answers

What is the function of the endonuclease during transcription termination?

It cleaves the RNA at the G/U rich element (C) Signup and view all the answers

What is the role of the Mpe1/RBBP6 protein during transcription termination?

It allows the endonuclease to dock onto the mammalian polyadenylation specificity factor (A) Signup and view all the answers

What is the purpose of the poly(A) tail in mRNA?

It helps stabilize mRNA (C) Signup and view all the answers

What is the function of the Xrn2 protein during transcription?

It is involved in RNA degradation (D) Signup and view all the answers

What is the role of the guanylytransferase enzyme during transcription?

It adds a guanosine nucleotide to the nascent RNA (C) Signup and view all the answers

Which RNA polymerase is responsible for transcribing mRNA and non-coding RNA?

Pol II (B) Signup and view all the answers

What is the function of the BRE element during transcription initiation?

Binds to INR (B) Signup and view all the answers

What is the role of the phosphorylated C-terminal domain during transcription?

Allows splicing, elongation, and capping factors to bind (C) Signup and view all the answers

What is the function of the triphosphatase enzyme during transcription?

Removes the 5'-triphosphate from the nascent RNA (A) Signup and view all the answers

What is the role of the CPSF100 protein during transcription termination?

Inhibits the endonuclease from rebinding to PAP (B) Signup and view all the answers

Which protein is responsible for recruiting Pol II during transcription initiation?

F (A) Signup and view all the answers

What is the function of the poly(A) tail in mRNA?

Stabilizes the mRNA (A) Signup and view all the answers

What is the role of the Cft2 protein during transcription termination?

Inhibits the endonuclease from rebinding to PAP (C) Signup and view all the answers

What is the function of the TaF1 protein during transcription initiation?

Inhibits the recruitment of Pol II (C) Signup and view all the answers

What is the function of the guanosine cap during transcription?

Allows splicing, elongation, and capping factors to bind (A) Signup and view all the answers

Which RNA polymerase is responsible for transcribing tRNA and catalytic RNA?

Pol III (C) Signup and view all the answers

What is the role of the INR element during transcription initiation?

Recruitment of Pol II (D) Signup and view all the answers

What is the function of the G/U rich element during transcription termination?

Binding of CF IA or CF II or CstF (C) Signup and view all the answers

What is the role of the protein complex during transcription elongation?

Elongation of mRNA (D) Signup and view all the answers

What is the function of the ATP molecule during transcription termination?

Addition of adenosine residues (D) Signup and view all the answers

What is the role of the nascent RNA during transcription?

Emergence from Pol II (B) Signup and view all the answers

What is the function of the chromatin remodeling during gene expression?

Transcription regulation (C) Signup and view all the answers

What is the role of the DPE element during transcription initiation?

Recognition of BRE (A) Signup and view all the answers

What is the function of the poly(A) polymerase during transcription termination?