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Questions and Answers

Which RNA polymerase is responsible for transcribing rRNA?

  • Pol II
  • Pol I (correct)
  • Pol III
  • All of the above

What is the function of the TBP protein in transcription initiation?

  • It binds to BRE and helps with kinking
  • It binds to INR and inhibits transcription
  • It binds to DPE and recruits Pol II
  • It binds to TATA box and kinks DNA (correct)

What is the role of the C-terminal domain in transcription?

  • It binds to the tail of Pol II and gets phosphorylated (correct)
  • It helps with chromatin remodeling
  • It inhibits Pol II recruitment
  • It is involved in RNA degradation

What is the function of the capping machinery during transcription?

<p>It removes the 5'-triphosphate from the nascent RNA (B)</p> Signup and view all the answers

What is the role of the poly(A)-binding proteins (PABAs) in mRNA stability?

<p>They help stabilize mRNA (C)</p> Signup and view all the answers

What is the function of the endonuclease during transcription termination?

<p>It cleaves the RNA at the G/U rich element (C)</p> Signup and view all the answers

What is the role of the Mpe1/RBBP6 protein during transcription termination?

<p>It allows the endonuclease to dock onto the mammalian polyadenylation specificity factor (A)</p> Signup and view all the answers

What is the purpose of the poly(A) tail in mRNA?

<p>It helps stabilize mRNA (C)</p> Signup and view all the answers

What is the function of the Xrn2 protein during transcription?

<p>It is involved in RNA degradation (D)</p> Signup and view all the answers

What is the role of the guanylytransferase enzyme during transcription?

<p>It adds a guanosine nucleotide to the nascent RNA (C)</p> Signup and view all the answers

Which RNA polymerase is responsible for transcribing mRNA and non-coding RNA?

<p>Pol II (B)</p> Signup and view all the answers

What is the function of the BRE element during transcription initiation?

<p>Binds to INR (B)</p> Signup and view all the answers

What is the role of the phosphorylated C-terminal domain during transcription?

<p>Allows splicing, elongation, and capping factors to bind (C)</p> Signup and view all the answers

What is the function of the triphosphatase enzyme during transcription?

<p>Removes the 5'-triphosphate from the nascent RNA (A)</p> Signup and view all the answers

What is the role of the CPSF100 protein during transcription termination?

<p>Inhibits the endonuclease from rebinding to PAP (B)</p> Signup and view all the answers

Which protein is responsible for recruiting Pol II during transcription initiation?

<p>F (A)</p> Signup and view all the answers

What is the function of the poly(A) tail in mRNA?

<p>Stabilizes the mRNA (A)</p> Signup and view all the answers

What is the role of the Cft2 protein during transcription termination?

<p>Inhibits the endonuclease from rebinding to PAP (C)</p> Signup and view all the answers

What is the function of the TaF1 protein during transcription initiation?

<p>Inhibits the recruitment of Pol II (C)</p> Signup and view all the answers

What is the function of the guanosine cap during transcription?

<p>Allows splicing, elongation, and capping factors to bind (A)</p> Signup and view all the answers

Which RNA polymerase is responsible for transcribing tRNA and catalytic RNA?

<p>Pol III (C)</p> Signup and view all the answers

What is the role of the INR element during transcription initiation?

<p>Recruitment of Pol II (D)</p> Signup and view all the answers

What is the function of the G/U rich element during transcription termination?

<p>Binding of CF IA or CF II or CstF (C)</p> Signup and view all the answers

What is the role of the protein complex during transcription elongation?

<p>Elongation of mRNA (D)</p> Signup and view all the answers

What is the function of the ATP molecule during transcription termination?

<p>Addition of adenosine residues (D)</p> Signup and view all the answers

What is the role of the nascent RNA during transcription?

<p>Emergence from Pol II (B)</p> Signup and view all the answers

What is the function of the chromatin remodeling during gene expression?

<p>Transcription regulation (C)</p> Signup and view all the answers

What is the role of the DPE element during transcription initiation?

<p>Recognition of BRE (A)</p> Signup and view all the answers

What is the function of the poly(A) polymerase during transcription termination?

<p>Addition of adenosine residues (D)</p> Signup and view all the answers

What is the role of the F protein during transcription initiation?

<p>Kinking of DNA (A)</p> Signup and view all the answers

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