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Questions and Answers
Which type of statistics should strictly be used on interval and/or ratio data?
Which type of statistics should strictly be used on interval and/or ratio data?
What is the key difference between interval and ratio data?
What is the key difference between interval and ratio data?
What is the purpose of normalizing data in statistical analysis?
What is the purpose of normalizing data in statistical analysis?
What should be the attributes of all measures in surveys using closed questions?
What should be the attributes of all measures in surveys using closed questions?
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What is the main advantage of using multiple measures of the same variable?
What is the main advantage of using multiple measures of the same variable?
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In what type of scale is the Likert scale categorized?
In what type of scale is the Likert scale categorized?
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What is the main challenge with RNAi?
What is the main challenge with RNAi?
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What is the length of small strands of RNA molecules involved in RNAi?
What is the length of small strands of RNA molecules involved in RNAi?
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Who won the 2006 Nobel Prize for their pioneering research into RNAi?
Who won the 2006 Nobel Prize for their pioneering research into RNAi?
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What is the potential application of RNAi in medical treatments?
What is the potential application of RNAi in medical treatments?
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What is the role of RNAi in addressing previously untreatable illnesses?
What is the role of RNAi in addressing previously untreatable illnesses?
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Who has put resources behind RNAi, heading a brain research institute and forming a company to develop the technique?
Who has put resources behind RNAi, heading a brain research institute and forming a company to develop the technique?
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What did the Nobel Assembly state about the current use of RNAi?
What did the Nobel Assembly state about the current use of RNAi?
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What was the initial focus of the research on RNAi?
What was the initial focus of the research on RNAi?
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What led to the understanding of RNAi's potential medical applications?
What led to the understanding of RNAi's potential medical applications?
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What contradicted established biological principles and opened up new possibilities in medical science?
What contradicted established biological principles and opened up new possibilities in medical science?
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What did David Baulcombe's research on viral resistance in plants contribute to?
What did David Baulcombe's research on viral resistance in plants contribute to?
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What did the test tube experiments demonstrate about RNAi's medical potential?
What did the test tube experiments demonstrate about RNAi's medical potential?
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What did Andrew Fire and Craig Mello win the 2006 Nobel Prize in medicine for?
What did Andrew Fire and Craig Mello win the 2006 Nobel Prize in medicine for?
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What are the options for dealing with missing data?
What are the options for dealing with missing data?
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What is the main difference between basic and applied research?
What is the main difference between basic and applied research?
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What did Andrew Fire's research on gene 'silencing' in nematode worms reveal?
What did Andrew Fire's research on gene 'silencing' in nematode worms reveal?
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What is the primary purpose of basic research?
What is the primary purpose of basic research?
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What was the outcome of the case study involving a plant scientist's research on petunia flowers?
What was the outcome of the case study involving a plant scientist's research on petunia flowers?
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What are the two research purposes mentioned in the text?
What are the two research purposes mentioned in the text?
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What are the options for dealing with missing data?
What are the options for dealing with missing data?
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What are the two main purposes of research mentioned in the text?
What are the two main purposes of research mentioned in the text?
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What distinguishes basic research from applied research?
What distinguishes basic research from applied research?
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What did the case study involving a plant scientist's research on petunia flowers lead to?
What did the case study involving a plant scientist's research on petunia flowers lead to?
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What was discovered through unexpected outcomes in research on nematode worms?
What was discovered through unexpected outcomes in research on nematode worms?
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What did Andrew Fire's research on gene 'silencing' in nematode worms reveal?
What did Andrew Fire's research on gene 'silencing' in nematode worms reveal?
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What did Andrew Fire and Craig Mello discover in 1998?
What did Andrew Fire and Craig Mello discover in 1998?
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What was the result of David Baulcombe's research on viral resistance in plants?
What was the result of David Baulcombe's research on viral resistance in plants?
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What did scientists find small stretches of double-stranded RNA interfering with, leading to a realization about tailored targeting of specific genes?
What did scientists find small stretches of double-stranded RNA interfering with, leading to a realization about tailored targeting of specific genes?
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What was recognized about RNAi's medical potential?
What was recognized about RNAi's medical potential?
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What did the test tube experiment with human cells and RNAi prompt research into?
What did the test tube experiment with human cells and RNAi prompt research into?
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What did Andrew Fire and Craig Mello win the 2006 Nobel Prize in medicine for?
What did Andrew Fire and Craig Mello win the 2006 Nobel Prize in medicine for?
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Study Notes
How a Petunia Experiment Led to Breakthrough in Cancer and AIDS Treatment
- In 1998, Andrew Fire and Craig Mello discovered RNA interference (RNAi), a process where double-stranded RNA can silence genes, contradicting the established "central dogma" of biology.
- David Baulcombe's research on viral resistance in plants led to the understanding that foreign RNA mimicked viruses, contributing to the fundamental understanding of RNAi.
- Scientists found small stretches of double-stranded RNA interfering with gene action in fruit flies and plants, leading to the realization that short, double-stranded RNAs could be tailored to target specific genes.
- RNAi's medical potential for turning off cancer-related genes, preventing virus infections, and treating tissue rejection and liver disease was recognized.
- In the test tube, scientists made human cells resistant to the polio virus and HIV using RNAi, prompting research into introducing short RNA strands directly into cells for medical use.
- Andrew Fire and Craig Mello won the 2006 Nobel Prize in medicine for their RNAi research, which was initially conducted on nematode worms and later found to occur in human cells.
- RNAi is being widely used in basic science to study gene function and holds promise for novel therapies in the future, according to the Nobel Assembly.
- The discovery of RNAi contradicted established biological principles and opened up new possibilities in medical science.
- The research on RNAi was initially focused on nematode worms and later expanded to human cells, demonstrating its potential for clinical treatments.
- RNAi has the potential to be a groundbreaking development in medical science and has already shown promise in basic science research.
- The discovery of RNAi led to the development of a process where double-stranded RNA can silence genes, contradicting established biological principles.
- RNAi has the potential to be a groundbreaking development in medical science, with applications ranging from heart disease to cancer treatment.
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Description
Explore the groundbreaking technique of RNA interference (RNAi) and its potential in revolutionizing medical treatments. Learn about the Nobel Prize-winning research, the applications of RNAi in targeting specific genes for various disorders, and the challenges and promises associated with this technique. Additionally, delve into the types of research and strategies for dealing with missing data in scientific studies, gaining insights into the different research purposes and their impact on advancing knowledge and solving real-world problems.
