RNA Degradation and Silencing Quiz

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Questions and Answers

What initiates RNA silencing (or RNA interference)?

  • Replication of double-stranded RNA viruses
  • Transcription of inverted repeats in DNA
  • Transcription of two different RNA molecules that are complementary to one another and pair
  • Presence of double-stranded RNA (correct)

Which enzyme cleaves double-stranded RNA to produce small interfering RNAs?

  • RNA polymerase
  • Ligase
  • Helicase
  • Dicer (correct)

What is the role of small interfering RNAs (siRNAs) in RNA silencing?

  • Pair with complementary sequences in DNA
  • Guide for the methylation of DNA sequences
  • Attract an RNA–protein complex that cleaves mRNA (correct)
  • Enhance transcription efficiency

Where do siRNAs serve as guides for methylation?

<p>DNA (C)</p> Signup and view all the answers

Which factor affects the stability of mRNA?

<p>Poly(A) tail (A)</p> Signup and view all the answers

What is the role of DNA-binding factors in transcription initiation?

<p>Influence the ability of RNA polymerase to initiate transcription (B)</p> Signup and view all the answers

How does RNA polymerase I terminate transcription in eukaryotes?

<p>By recruiting termination factors (B)</p> Signup and view all the answers

Which polymerase does not require a hairpin structure for transcription termination?

<p>RNA polymerase III (D)</p> Signup and view all the answers

What is a common feature of eukaryotic gene regulation that differs from bacterial cells?

<p>Use of activators for gene expression (A)</p> Signup and view all the answers

How is gene expression influenced by chromatin structure in eukaryotic cells?

<p>Through modulation by histone proteins (D)</p> Signup and view all the answers

What is the role of GAL80 in transcriptional regulation?

<p>Binding to GAL4, preventing it from activating transcription (A)</p> Signup and view all the answers

How do repressors in eukaryotic cells differ from repressors in bacteria?

<p>Repressors in eukaryotic cells directly block RNA polymerase (D)</p> Signup and view all the answers

What is the function of insulators in gene regulation?

<p>Blocking the effect of enhancers in a position-dependent manner (A)</p> Signup and view all the answers

How does alternative splicing impact gene expression?

<p>Allows a pre-mRNA to be spliced in multiple ways, generating different proteins (C)</p> Signup and view all the answers

Which protein plays a role in enhancing the production of mRNA encoding the small t antigen?

<p>Splicing factor 2 (SF2) (C)</p> Signup and view all the answers

How does mRNA stability influence gene expression?

<p>Affects the amount of mRNA available for translation (A)</p> Signup and view all the answers

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