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Questions and Answers
What class of drug is Risedronate?
What class of drug is Risedronate?
What are the indications for Risedronate?
What are the indications for Risedronate?
Treatment and prevention of postmenopausal osteoporosis.
What is the mechanism of action of Risedronate?
What is the mechanism of action of Risedronate?
Inhibits resorption of bone by inhibiting osteoclast activity.
The recommended route and dose for Risedronate is ___ mg weekly or ___ mg daily.
The recommended route and dose for Risedronate is ___ mg weekly or ___ mg daily.
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Which of the following are side effects of Risedronate? (Select all that apply)
Which of the following are side effects of Risedronate? (Select all that apply)
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What precautions should be taken when administering Risedronate?
What precautions should be taken when administering Risedronate?
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Risedronate should be administered first thing in the morning with ___ to ___ ounces of plain water.
Risedronate should be administered first thing in the morning with ___ to ___ ounces of plain water.
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What are contraindications for taking Risedronate? (Select all that apply)
What are contraindications for taking Risedronate? (Select all that apply)
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What nursing actions are necessary before Risedronate treatment?
What nursing actions are necessary before Risedronate treatment?
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Study Notes
Risedronate (Actonel) Overview
- Class: Bisphosphonate; used primarily to inhibit bone resorption.
- Focuses on preventing and treating postmenopausal osteoporosis, which can lead to a significant loss of up to 35% of bone mass.
Mechanism of Action
- Works by inhibiting osteoclast activity, crucial for bone resorption.
- Aims to reverse osteoporosis progression and lower fracture risk.
Dosage and Administration
- Standard dosage is either 70 mg weekly or 10 mg daily.
- Available in tablet form and extended-release (ER) formulations.
Potential Side Effects
- Notable side effects include:
- Atrial fibrillation and various gastrointestinal issues (esophageal cancer, ulcers, esophagitis).
- Common symptoms: gastritis, flatulence, nausea, taste alterations, vomiting.
- Musculoskeletal pain, increased risk of femur fractures, osteonecrosis of the jaw, erythema, photosensitivity, and rash.
Precautions
- Calcium carbonate supplements can reduce absorption; monitor calcium levels before treatment.
- Hypocalcemia and vitamin D deficiencies must be resolved prior to starting therapy.
- Administer on an empty stomach with 6-8 ounces of plain water, and maintain a half-hour gap before other intake (food, medications).
- Tablets should remain intact—do not crush, break, or chew.
Contraindications
- Contraindicated in patients with esophageal abnormalities, those unable to remain upright for 30 minutes, and individuals with renal insufficiency.
- History of upper gastrointestinal disorders and dental complications (e.g., invasive procedures, poor oral hygiene) can increase jaw osteonecrosis risk.
Nursing Actions
- Pre-treatment assessment for low bone mass is crucial.
- Monitor calcium levels and resolve deficiencies before starting treatment.
- Educate patients on the proper administration guidelines and potential side effects.
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Description
This quiz features flashcards focused on Risedronate, also known as Actonel, highlighting its drug class, indications, and mechanism of action. Test your knowledge about this important medication used in the treatment of osteoporosis and understand how it functions in the body.
