5 Questions
What is the mechanism of action of rifamycins?
Inhibiting RNA polymerase and preventing transcription
Which bacteria are rifamycins generally good against?
Mycobacteria
What is the main concern when patients receive rifamycins?
Drug interactions
In addition to mycobacteria, rifamycins are sometimes added to other therapies to treat which type of infection?
MRSA infections
What distinguishes rifamycins from other protein synthesis inhibitors?
They inhibit RNA polymerase and prevent transcription
Test your knowledge about rifamycins, including rifampin, rifabutin, rifapentine, and rifaximin, and their role in treating tuberculosis and MAC. Learn about how these drugs inhibit transcription of DNA to bacterial messenger RNA and their impact on the cytochrome P450 system.
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