Central Dogma

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Questions and Answers

What process rewrites the DNA code into RNA using the same nucleotide 'language'?

  • Translation
  • Polyadenylation
  • Splicing
  • Transcription (correct)

In eukaryotes, what must mRNA do before it can exit the nucleus?

  • Add poly-A tail
  • Get processed by splicing
  • Pass through nuclear pores (correct)
  • Undergo translation

What is the sequence of events in protein construction from DNA to amino acids?

  • Translation >> Transcription >> Replication
  • Replication >> Transcription >> Translation
  • Replication >> Translation >> Transcription
  • Transcription >> Translation >> Replication (correct)

Which of the following correctly describes alternative RNA splicing?

<p>Allows genes to encode multiple polypeptides (B)</p> Signup and view all the answers

What is the function of tRNA during translation?

<p>Carries amino acids to the ribosome (A)</p> Signup and view all the answers

Which feature of the genetic code allows for more than one codon to code for the same amino acid?

<p>'Redundancy' of the code (B)</p> Signup and view all the answers

What is the main function of tRNA in translation?

<p>Interpreting the mRNA codons to assemble the correct amino acids (C)</p> Signup and view all the answers

Which component of the ribosome is crucial for coordinating the functioning of mRNA and tRNA during translation?

<p>Ribosomal RNAs (D)</p> Signup and view all the answers

At what point does elongation stop during translation?

<p>When tRNA delivers an amino acid to the A site (D)</p> Signup and view all the answers

What happens to the completed polypeptide during translation termination?

<p>It is released from the ribosome (B)</p> Signup and view all the answers

Which component of tRNA is responsible for recognizing the appropriate codons in mRNA?

<p>Anticodon (B)</p> Signup and view all the answers

What role do ribosomal subunits play in translation?

<p>Dissociate from each other after polypeptide synthesis (B)</p> Signup and view all the answers

What is the function of the P site in a ribosome?

<p>Peptidyl-tRNA binding site (D)</p> Signup and view all the answers

Which subunit of the ribosome contains the large 5′ mRNA binding site?

<p>Large subunit (C)</p> Signup and view all the answers

What is the role of the E site in translation?

<p>Exit site for tRNA (A)</p> Signup and view all the answers

Which base of the RNA codon determines the amino acid in the translation process?

<p>Second base (B)</p> Signup and view all the answers

How do certain antibiotic drugs act selectively on bacterial ribosomes?

<p>By affecting the tRNA binding sites in bacterial ribosomes (A)</p> Signup and view all the answers

What is the significance of ribosomal differences between bacteria and eukaryotes?

<p>Medically, antibiotics can target bacterial ribosomes specifically (A)</p> Signup and view all the answers

During which process are genetic messages produced in the form of RNA?

<p>Transcription (B)</p> Signup and view all the answers

What is the binding site for RNA polymerase in the process of transcription?

<p>Promoter (D)</p> Signup and view all the answers

Which molecule is responsible for carrying amino acids to the ribosome during protein synthesis?

<p>tRNA (C)</p> Signup and view all the answers

What occurs during translation in protein synthesis?

<p>Synthesis of proteins under the direction of RNA (B)</p> Signup and view all the answers

Which component is directly involved in creating polypeptides at the ribosome?

<p>tRNA (A)</p> Signup and view all the answers

What is the role of RNA polymerase in gene expression?

<p>Transcribing DNA into RNA (D)</p> Signup and view all the answers

How does a base substitution mutation differ from a frameshift mutation?

<p>Base substitution mutations cause a change in the amino acid sequence, while frameshift mutations alter the reading frame. (D)</p> Signup and view all the answers

What is the outcome of a missense mutation?

<p>A new protein with an improved function is produced. (D)</p> Signup and view all the answers

How do nucleotide insertions differ from nucleotide deletions?

<p>Insertions alter the reading frame, while deletions may have no effect at all. (C)</p> Signup and view all the answers

What is the consequence of a nonsense mutation?

<p>An amino acid is changed into a stop codon. (A)</p> Signup and view all the answers

In what way does a frameshift mutation affect the genetic message?

<p>It alters the reading frame of the genetic message. (C)</p> Signup and view all the answers

Which type of mutation could potentially lead to an improved protein function?

<p>Missense mutation (B)</p> Signup and view all the answers

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