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Rheumatoid Factor (RF) Quiz
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Rheumatoid Factor (RF) Quiz

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Questions and Answers

What is the role of the complement system in the immune system?

  • It produces antibodies against foreign substances.
  • It helps in blood clotting.
  • It regulates hormonal balance in the body.
  • It provides a defense mechanism against microbial invaders. (correct)

    • Why is ANA testing not suitable as a screening test for rheumatic or nonrheumatic diseases in asymptomatic individuals?

  • It is expensive.
  • It is time-consuming.
  • It requires specialized equipment.
  • It has low specificity. (correct)

    • Which diseases can result in hypocomplementemia due to the formation of immune complexes?

  • Diabetes and hypertension
  • SLE and RA (correct)
  • Osteoarthritis and gout
  • Influenza and common cold

    • Why should new complement test results be compared with previous test results rather than reference ranges?

    <p>Reference ranges are relatively wide.</p> Signup and view all the answers

    What does the CH50 test measure?

    <p>The ability of serum to lyse 50% of a standard suspension of sheep erythrocytes.</p> Signup and view all the answers

    Which complement protein appears to be more sensitive to small changes in complement activation?

    <p>C4</p> Signup and view all the answers

    What is the normal value for Rheumatoid factor (RF)?

    <p>&lt; 1:20 or less than 20 international units / mL</p> Signup and view all the answers

    What does a titer of > 1:20 or a conc > 20 international units / mL generally indicate?

    <p>A positive result for RF</p> Signup and view all the answers

    Which part of IgG do Rheumatoid factors (RFs) abnormally target?

    <p>Fraction crystallizable (Fc) portion</p> Signup and view all the answers

    What is the most common disease associated with Rheumatoid factors (RFs)?

    <p>Rheumatoid arthritis (RA)</p> Signup and view all the answers

    What is the significance of having both positive RF and positive anti-CCP antibody?

    <p>99.5% specificity for RA</p> Signup and view all the answers

    What is the normal value for anti-CCP antibodies?

    <p>&lt; 20 EU/mL (Eliza unite)</p> Signup and view all the answers

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