Rheumatoid Arthritis
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Questions and Answers

What should be assessed for a patient with latent TB and never been treated?

  • Liver enzymes only
  • Lung function
  • Kidney function only
  • Hepatitis B and hepatitis C (correct)

    • Why is liver and kidney monitoring recommended for most DMARD therapy?

  • It has no impact on liver or kidney
  • To check for respiratory function
  • To monitor blood pressure
  • It can cause elevation of the liver enzymes and affect kidney function (correct)

    • What is the most common radiographic study used to track disease progression?

  • Plain x-ray (correct)
  • Ultrasound
  • MRI
  • CT scan

    • When should joint damage be followed as indicated?

    <p>Within the first 6 to 12 months of diagnosis</p> Signup and view all the answers

    What is the purpose of using X-ray, ultrasound, or both of the hands, wrists, and feet?

    <p>Establishing a baseline for joint evaluation and assessing the joints for erosions and synovitis</p> Signup and view all the answers

    Why is MRI also useful in addition to plain x-ray for disease evaluation?

    <p>To detect small erosions that may not be visible on x-ray or ultrasound</p> Signup and view all the answers

    If a patient tests positive for hepatitis, what should be done prior to starting medication?

    <p>The infection should be treated</p> Signup and view all the answers

    What could impact treatment strategies if positive for hepatitis B and hepatitis C?

    <p>Positive hepatitis B and hepatitis C</p> Signup and view all the answers

    Why is reactivation of latent TB a concern?

    <p>It can lead to active TB infection</p> Signup and view all the answers

    What is the impact of DMARD therapy on liver and kidney function?

    <p>It can cause elevation of the liver enzymes and affect kidney function</p> Signup and view all the answers

    What is the approximate percentage of the population worldwide affected by rheumatoid arthritis?

    <p>1% to 2%</p> Signup and view all the answers

    At what age does the onset of rheumatoid arthritis commonly occur?

    <p>Between the third and sixth decade of life</p> Signup and view all the answers

    What is rheumatoid arthritis referred to when it occurs after the age of 65?

    <p>Elderly onset RA</p> Signup and view all the answers

    Which of the following is identified as a modifiable risk factor for rheumatoid arthritis?

    <p>Obesity</p> Signup and view all the answers

    What is the main consequence of pannus formation in rheumatoid arthritis?

    <p>Loss of articular surfaces and joint motion</p> Signup and view all the answers

    What is the main consequence of the RA inflammatory process?

    <p>Implication in other disease processes</p> Signup and view all the answers

    What is the exact mechanism of action for the etiology of RA according to the text?

    <p>Genetic predisposition and development of immunologically mediated joint inflammation</p> Signup and view all the answers

    What does the RA synovium break down, leading to pannus formation?

    <p>Collagen</p> Signup and view all the answers

    What are the additional risks identified for rheumatoid arthritis in the text?

    <p>Smoking and environmental influences</p> Signup and view all the answers

    What is the incidence of RA after the sixth decade of life according to the text?

    <p>Increases</p> Signup and view all the answers

    What initial clinical manifestations are associated with Rheumatoid Arthritis?

    <p>Symmetric joint pain and morning stiffness lasting over an hour</p> Signup and view all the answers

    What is used to evaluate Rheumatoid Arthritis activity and guide treatment decisions?

    <p>Disease activity scores</p> Signup and view all the answers

    Which antibody has a high specificity for detecting Rheumatoid Arthritis?

    <p>Antibodies to cyclic citrullinated peptide (antiCCP)</p> Signup and view all the answers

    How is Rheumatoid Arthritis diagnosed?

    <p>Based on a point system involving joint involvement, serology, acute phase reactants, and duration of symptoms</p> Signup and view all the answers

    What are some extra-articular features of Rheumatoid Arthritis?

    <p>Fever, weight loss, fatigue</p> Signup and view all the answers

    Which laboratory test for Rheumatoid Arthritis indicates active disease?

    <p>Elevated ESR and CRP</p> Signup and view all the answers

    What is impacted by Rheumatoid Arthritis inflammation?

    <p>Nervous system</p> Signup and view all the answers

    Where does Rheumatoid Arthritis typically start?

    <p>Small joints</p> Signup and view all the answers

    What are the initial symptoms of Rheumatoid Arthritis?

    <p>Symmetric joint pain and morning stiffness lasting over an hour</p> Signup and view all the answers

    What may early Rheumatoid Arthritis stages cause due to inflammation?

    <p>Limitation in joint function, leading to joint deformities and contractures</p> Signup and view all the answers

    Study Notes

    Rheumatoid Arthritis: Clinical Manifestations and Assessment

    • Rheumatoid arthritis (RA) may interfere with the production of high-density lipoprotein cholesterol, contributing to atherosclerosis.
    • The nervous system is impacted by RA inflammation, leading to neuropathies, paresthesias, and potential axonal degeneration.
    • Criteria for diagnosing RA involve a point system based on joint involvement, serology, acute phase reactants, and duration of symptoms.
    • Initial clinical manifestations of RA include symmetric joint pain and morning stiffness lasting over an hour.
    • RA symptoms vary by disease stage, with classic symptoms including joint pain, swelling, warmth, erythema, and lack of function.
    • RA typically starts in small joints, progressing to knees, shoulders, hips, elbows, and other joints.
    • Early RA stages may cause limitation in joint function due to inflammation, leading to joint deformities and contractures.
    • RA is a systemic disease with extra-articular features like fever, weight loss, fatigue, anemia, lymph node enlargement, Raynaud’s phenomenon, and rheumatoid nodules.
    • Assessment findings associated with RA include rheumatoid nodules, joint inflammation, and certain laboratory findings.
    • Disease activity scores are used to evaluate RA activity and guide treatment decisions.
    • Antibodies to cyclic citrullinated peptide (antiCCP) have a high specificity for detecting RA.
    • Laboratory tests for RA include rheumatoid factor, ESR, CRP, and CBC, with elevated ESR and CRP indicating active disease.

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    Related Documents

    Rheumatoid Arthritis PDF

    Description

    Test your knowledge of rheumatoid arthritis (RA) clinical manifestations and assessment with this quiz. Explore key points such as joint involvement, serology, acute phase reactants, and disease activity scores. Learn about the impact of RA on the nervous system, extra-articular features, and laboratory findings.

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