30 Questions
What is the estimated worldwide incidence of rheumatoid arthritis?
1% to 2%
At what age does the onset of rheumatoid arthritis commonly occur?
Third and sixth decade of life
What is rheumatoid arthritis that occurs after the age of 65 referred to as?
Elderly onset RA
Which of the following is NOT identified as a risk factor for rheumatoid arthritis?
Regular exercise
What is the main consequence of the RA inflammatory process on joint motion?
Loss of articular surfaces and joint motion
What does the RA synovium break down, leading to pannus formation?
Collagen
What is the suspected mechanism of action for the etiology of RA?
Genetic predisposition and immunologically mediated joint inflammation
What is the gender-based incidence ratio of rheumatoid arthritis?
Three times higher in females
What is the term for RA that occurs after the age of 65?
Elderly onset RA
Which factor has been identified as a modifiable risk factor for rheumatoid arthritis?
Smoking
Which infection should be treated prior to starting medication for a patient with latent TB?
Hepatitis B
What is recommended for most DMARD therapy due to its potential impact on liver and kidney function?
Liver and kidney monitoring
Which radiographic study is the most common for tracking disease progression?
Plain x-ray
What can be useful to detect small erosions that may not be visible on x-ray or ultrasound?
MRI
When may joint damage occur within the first 6 to 12 months of diagnosis?
Within the first 6 to 12 months
What should be assessed for patients with latent TB who have never been treated?
Reactivation of the infection
What should be assessed if a client tests positive for hepatitis?
Treatment of the infection
What can cause elevation of the liver enzymes and affect kidney function?
DMARD therapy
What can be useful in establishing a baseline for joint evaluation and assessing the joints for erosions and synovitis?
X-ray, ultrasound, or both
What is recommended for tracking disease progression due to its reliability and reproducibility?
Plain x-ray
What are the criteria for classifying Rheumatoid Arthritis?
Joint involvement, serology, acute phase reactants, and symptom duration
What are the initial clinical manifestations of Rheumatoid Arthritis?
Symmetric joint pain and morning joint stiffness
Which antibodies are used for diagnosing Rheumatoid Arthritis?
Rheumatoid factor and antiCCP antibodies
What is used to evaluate disease activity and monitor treatment efficacy in Rheumatoid Arthritis?
Disease activity score
Which of the following are elevated in acute phases of Rheumatoid Arthritis and useful in monitoring active disease?
ESR and CRP
What can Rheumatoid Arthritis lead to in terms of joint and soft tissue?
Joint deformities, soft tissue deformity, and extra-articular features
What is affected by the inflammatory process of Rheumatoid Arthritis, causing neuropathies and paresthesias?
The nervous system
What should be assessed to establish baseline count in Rheumatoid Arthritis, as anemia and elevated platelets may be present due to inflammation?
CBC
Where does joint involvement begin in Rheumatoid Arthritis?
Small joints
What is considered antiatherosclerotic and interferes with the production in Rheumatoid Arthritis?
High-density lipoprotein cholesterol
Study Notes
Rheumatoid Arthritis: Clinical Manifestations and Assessment
- RA interferes with the production of high-density lipoprotein cholesterol, considered antiatherosclerotic
- The nervous system is affected by RA inflammatory process, causing neuropathies and paresthesias
- Criteria for classifying RA include joint involvement, serology, acute phase reactants, and symptom duration
- Initial clinical manifestations of RA include symmetric joint pain and morning joint stiffness
- Classic symptoms of RA include symmetric joint pain, swelling, warmth, erythema, and lack of function
- Joint involvement begins in small joints and progresses to knees, shoulders, hips, elbows, and ankles
- RA can lead to joint deformities, soft tissue deformity, and extra-articular features
- Assessment findings for RA include rheumatoid nodules, joint inflammation, and laboratory findings
- Disease activity score is used to evaluate disease activity and monitor treatment efficacy
- Rheumatoid factor and antiCCP antibodies are used for diagnosing RA
- ESR and CRP are elevated in acute phases of RA, useful in monitoring active disease
- CBC should be assessed to establish baseline count, anemia and elevated platelets may be present due to inflammation
Test your knowledge of Rheumatoid Arthritis clinical manifestations and assessment with this quiz. Learn about the criteria for classifying RA, initial symptoms, joint involvement, assessment findings, and laboratory tests used for diagnosis and monitoring.
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