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What is the primary characteristic of rheumatic fever?
What is the primary characteristic of rheumatic fever?
Which age group is most commonly affected by rheumatic fever?
Which age group is most commonly affected by rheumatic fever?
According to Jones criteria, which combination of symptoms indicates a highly probable diagnosis of rheumatic fever?
According to Jones criteria, which combination of symptoms indicates a highly probable diagnosis of rheumatic fever?
What percentage of patients with acute rheumatic fever are affected by rheumatic carditis?
What percentage of patients with acute rheumatic fever are affected by rheumatic carditis?
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Which of the following is a serious consequence of rheumatic carditis?
Which of the following is a serious consequence of rheumatic carditis?
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How does tachycardia associated with rheumatic fever usually present?
How does tachycardia associated with rheumatic fever usually present?
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What is the tendency for rheumatic fever to recur in a child who has previously had an attack?
What is the tendency for rheumatic fever to recur in a child who has previously had an attack?
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Which demographic is at a higher risk of developing rheumatic fever?
Which demographic is at a higher risk of developing rheumatic fever?
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What is a characteristic feature of arthritis as described?
What is a characteristic feature of arthritis as described?
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Which of the following joints are typically affected by arthritis?
Which of the following joints are typically affected by arthritis?
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What happens to arthritis symptoms with the start of salicylate therapy?
What happens to arthritis symptoms with the start of salicylate therapy?
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What is true regarding the chronic effects of arthritis?
What is true regarding the chronic effects of arthritis?
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Which percentage of patients is affected by rheumatic chorea according to the findings?
Which percentage of patients is affected by rheumatic chorea according to the findings?
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What is a noted investigation useful in suspected cases of rheumatic fever?
What is a noted investigation useful in suspected cases of rheumatic fever?
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Which of the following is a complication of rheumatic fever?
Which of the following is a complication of rheumatic fever?
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What is the recommended primary prophylaxis for preventing rheumatic fever?
What is the recommended primary prophylaxis for preventing rheumatic fever?
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Study Notes
Definition
- Rheumatic fever (RF) is an inflammatory disease affecting connective tissues, particularly joints and the heart.
- Can also involve the CNS, skin, and subcutaneous tissues.
Etiology
- RF is a complication of group A beta-hemolytic streptococcal infections, particularly after upper respiratory tract infections.
Epidemiology
- Affects males and females equally, typically between ages 5-15.
- Occurs in 3% of untreated or inadequately treated streptococcal infections.
- Recurrence rate in children with previous attacks is about 50%.
- Family history increases occurrence chance by 10%.
- More prevalent in overcrowded and impoverished communities.
Clinical Picture and Diagnosis
- No singular clinical or laboratory test confirms RF; diagnosis is probable with Jones criteria.
- Jones criteria:
- Two major criteria + evidence of prior streptococcal infection.
- One major and two minor criteria + evidence of prior streptococcal infection.
Major Clinical Manifestations
Carditis
- Affects 50-70% of patients within the first three weeks of acute RF.
- Involves all heart layers: myocardium, endocardium, and pericardium.
- Can lead to chronic valvular damage; mild cases may go undetected.
- Symptoms include cardiomegaly, tachycardia, rapid sleeping pulse, arrhythmias, and congestive heart failure.
Arthritis
- Characterized by red, hot, swollen, tender joints with limited movement, typically affecting large joints.
- Symptoms often resolve within a week without treatment or within a day with salicylate therapy.
- Does not lead to chronic joint disease.
Rheumatic Chorea
- Occurs in about 10% of cases, typically 2-6 months post-infection.
- May be the sole manifestation or accompany carditis.
Subcutaneous Nodules
- Found in about 1% of cases, mainly in those with severe carditis.
- Appear as pea-sized, firm, painless nodules over bony prominences.
Other Investigations
- Echocardiography is crucial for suspected RF; detects valvular regurge, cardiac dilatation, decreased function, and pericardial effusion.
Differential Diagnosis
- Exclude carditis from viral myocarditis, arthritis from rheumatoid arthritis, chorea from degenerative diseases, and pericarditis from various causes including tuberculosis and viral infections.
Complications
- Chronic valvular disease, heart failure, infective endocarditis, arrhythmias, thromboembolism leading to stroke, and potentially death from severe carditis.
Primary Prophylaxis
- Early treatment of streptococcal infections is vital to prevent RF.
- Prophylactic options include:
- Benzathine penicillin 1,200,000 units IM once.
- Procaine penicillin 400,000 units/day for 10 days.
- Oral penicillin V 125-250mg/dose three times daily for 10 days.
- Erythromycin 40mg/kg/day orally in three divided doses.
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Description
This quiz covers the key concepts of rheumatic fever (RF), including its definition, etiology, and involvement of various body systems. It is designed for nursing students and faculty at Sohag University, providing essential knowledge about this inflammatory disease. Test your understanding of RF and its complications.