Rheumatic Fever and Jones Criteria

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Questions and Answers

A 10-year-old child presents with new onset migratory polyarthritis, fever, and a rash following a recent sore throat. Which of the following is the most likely underlying etiology of these findings?

  • Type III hypersensitivity reaction with immune complex deposition in joints
  • Direct bacterial invasion of the synovium by Streptococcus pyogenes
  • Molecular mimicry and antibody cross-reactivity following Group A streptococcal infection (correct)
  • Type II hypersensitivity reaction to streptococcal M protein

According to the revised Jones criteria, which of the following is considered a major criterion for the diagnosis of acute rheumatic fever?

  • Prolonged PR interval on ECG
  • Polyarthritis (correct)
  • Elevated erythrocyte sedimentation rate
  • Fever ≥ 38.5°C

A patient diagnosed with acute rheumatic fever is being treated. Which valvular lesion is the most common long-term sequelae of this condition?

  • Aortic stenosis
  • Tricuspid regurgitation
  • Mitral stenosis (correct)
  • Pulmonary regurgitation

A patient with suspected aortic stenosis is being evaluated. Which of the following physical exam findings is most suggestive of severe aortic stenosis?

<p>Late peaking systolic ejection murmur with diminished and delayed carotid pulses (B)</p> Signup and view all the answers

In a patient with aortic stenosis, which of the following symptoms indicates advanced disease and a poorer prognosis?

<p>Exertional syncope (D)</p> Signup and view all the answers

Echocardiography is performed on a patient with suspected aortic stenosis. Which echocardiographic finding is consistent with severe aortic stenosis?

<p>Aortic valve area of 0.8 cm² (A)</p> Signup and view all the answers

A 75-year-old patient with symptomatic severe aortic stenosis is deemed a poor surgical candidate. Which of the following is a less invasive treatment option to provide symptomatic relief?

<p>Percutaneous balloon valvuloplasty (C)</p> Signup and view all the answers

Which of the following is the primary pathophysiological mechanism in chronic aortic regurgitation?

<p>Volume overload of the left ventricle (D)</p> Signup and view all the answers

A patient with chronic aortic regurgitation may remain asymptomatic for many years due to which compensatory mechanism?

<p>Eccentric left ventricular hypertrophy (A)</p> Signup and view all the answers

Which of the following physical exam findings is classic for aortic regurgitation?

<p>Wide pulse pressure (C)</p> Signup and view all the answers

An Austin Flint murmur is associated with which valvular heart disease?

<p>Aortic regurgitation (A)</p> Signup and view all the answers

Which class of medications is generally contraindicated in patients with aortic regurgitation?

<p>Beta-blockers (D)</p> Signup and view all the answers

According to the provided information, surgical intervention is recommended for chronic aortic regurgitation when the left ventricular ejection fraction falls below what percentage?

<p>55% (C)</p> Signup and view all the answers

A 75-year-old male presents to the emergency department with acute chest tightness and shortness of breath. Physical exam reveals a holosystolic murmur best heard at the apex. ECG shows evidence of myocardial infarction. Which valvular disease is most likely in this scenario?

<p>Mitral regurgitation (D)</p> Signup and view all the answers

What is the most common etiology of mitral stenosis?

<p>Rheumatic heart disease (D)</p> Signup and view all the answers

Which of the following is a characteristic auscultatory finding in mitral stenosis?

<p>Opening snap followed by a diastolic rumble (D)</p> Signup and view all the answers

A patient with mitral stenosis develops atrial fibrillation. What is the most significant hemodynamic consequence of atrial fibrillation in this patient population?

<p>Loss of atrial contribution to ventricular filling and increased heart rate leading to reduced diastolic filling time (B)</p> Signup and view all the answers

What is the primary treatment strategy for symptomatic mitral stenosis?

<p>Surgical or percutaneous intervention to relieve the mitral valve obstruction (D)</p> Signup and view all the answers

Mitral regurgitation is defined as:

<p>Incompetence of the mitral valve causing systolic flow from the left ventricle to the left atrium (A)</p> Signup and view all the answers

A loud, high-pitched pansystolic murmur radiating to the axilla is most characteristic of which valvular lesion?

<p>Mitral regurgitation (B)</p> Signup and view all the answers

What is the most common cause of mitral valve prolapse?

<p>Myxomatous degeneration (C)</p> Signup and view all the answers

Which auscultatory finding is most specific for mitral valve prolapse?

<p>Mid-systolic click (A)</p> Signup and view all the answers

In tricuspid stenosis, the diastolic murmur is typically augmented by:

<p>Inspiration (C)</p> Signup and view all the answers

Functional tricuspid regurgitation is most commonly secondary to:

<p>Pulmonary hypertension and right ventricular dilatation (A)</p> Signup and view all the answers

A patient with tricuspid regurgitation is likely to exhibit which of the following physical exam findings related to venous congestion?

<p>Jugular venous distension with prominent V waves and pulsatile liver (D)</p> Signup and view all the answers

Pulmonic stenosis is most commonly caused by:

<p>Congenital heart disease (D)</p> Signup and view all the answers

A harsh systolic ejection murmur heard best at the 2nd left intercostal space, often with a palpable thrill, is characteristic of:

<p>Pulmonic stenosis (D)</p> Signup and view all the answers

Pulmonic regurgitation is most commonly associated with:

<p>Pulmonary hypertension (B)</p> Signup and view all the answers

Which of the following best describes the murmur of pulmonic regurgitation due to pulmonary hypertension (Graham Steell murmur)?

<p>High-pitched diastolic decrescendo murmur at the left upper sternal border (C)</p> Signup and view all the answers

According to current guidelines, endocarditis prophylaxis is recommended for patients with acquired valvular heart disease in which of the following scenarios?

<p>Patients with a history of bacterial endocarditis or prosthetic valve (D)</p> Signup and view all the answers

A 52-year-old female presents with progressive dyspnea and palpitations. Physical exam reveals bounding peripheral pulses, wide pulse pressure, and a 4/6 diastolic decrescendo murmur. Which valvular disease is most consistent with these findings?

<p>Aortic regurgitation (B)</p> Signup and view all the answers

A 45-year-old male with a history of rheumatic fever presents with progressive dyspnea and palpitations. On auscultation, an opening snap followed by a diastolic rumble is heard. Which valvular disease is most likely?

<p>Mitral stenosis (C)</p> Signup and view all the answers

A 50-year-old male presents with exertional chest pain and shortness of breath. Physical exam reveals a delayed carotid upstroke and a 3/6 late-peaking systolic ejection murmur radiating to the neck. Which valvular disease is most likely?

<p>Aortic stenosis (C)</p> Signup and view all the answers

Which of the following Jones criteria is specific to rheumatic fever and is considered a major manifestation?

<p>Sydenham's chorea (A)</p> Signup and view all the answers

A patient with known aortic stenosis and exertional angina is being evaluated for aortic valve replacement. Which of the following stress tests is generally contraindicated in this patient population?

<p>All of the above are contraindicated (D)</p> Signup and view all the answers

A patient with chronic aortic regurgitation who is initially asymptomatic develops symptoms of dyspnea on exertion and orthopnea. Which of the following is the most likely underlying mechanism for the development of these symptoms?

<p>Left ventricular systolic dysfunction (C)</p> Signup and view all the answers

In mitral stenosis, which of the following electrocardiogram (ECG) findings is most suggestive of advanced disease and pulmonary hypertension?

<p>Right ventricular hypertrophy and right axis deviation (D)</p> Signup and view all the answers

A patient with mitral regurgitation presents with acute onset of severe dyspnea, hypotension, and pulmonary edema. Auscultation reveals a new holosystolic murmur. Which of the following is the most appropriate immediate management strategy?

<p>Urgent surgical mitral valve repair or replacement (C)</p> Signup and view all the answers

Which type of prosthetic valve is typically preferred for tricuspid valve replacement due to the high risk of thrombosis with mechanical valves even with adequate anticoagulation?

<p>Porcine bioprosthetic valve (B)</p> Signup and view all the answers

In a patient with pulmonic stenosis, which of the following clinical features is most likely to be present in severe cases?

<p>Jugular venous distension with prominent 'a' wave (C)</p> Signup and view all the answers

The murmur of pulmonic regurgitation (PR) can be difficult to distinguish from which other valvular regurgitation murmur by auscultation alone?

<p>Aortic regurgitation (D)</p> Signup and view all the answers

What is the primary treatment strategy for pulmonic regurgitation?

<p>Treatment directed at the underlying cause of pulmonary hypertension (B)</p> Signup and view all the answers

Rheumatic fever is primarily a sequelae of infection with which of the following bacterial organisms?

<p>Group A beta-hemolytic streptococci (B)</p> Signup and view all the answers

According to the revised Jones criteria, which of the following is classified as a MINOR criterion for the diagnosis of acute rheumatic fever?

<p>Fever (B)</p> Signup and view all the answers

A 9-year-old child is diagnosed with acute rheumatic fever. Which of the following valvular lesions is most commonly affected in the late sequelae of this condition?

<p>Mitral valve (A)</p> Signup and view all the answers

Which of the following clinical manifestations is a MAJOR criterion for acute rheumatic fever, as defined by the Jones criteria?

<p>Erythema marginatum (B)</p> Signup and view all the answers

A child with suspected acute rheumatic fever presents with involuntary, jerky movements. Which of the following major Jones criteria is most consistent with this presentation?

<p>Sydenham's chorea (B)</p> Signup and view all the answers

What is the recommended duration of intramuscular benzathine penicillin G prophylaxis for secondary prevention of rheumatic fever in a child with documented rheumatic heart disease?

<p>5-10 years (D)</p> Signup and view all the answers

Which of the following is the most common etiology of aortic stenosis in older adults in developed countries?

<p>Calcific aortic stenosis (D)</p> Signup and view all the answers

A patient with aortic stenosis develops angina, syncope, and heart failure. These symptoms typically indicate:

<p>Severe aortic stenosis (B)</p> Signup and view all the answers

On physical examination of a patient with aortic stenosis, which of the following pulse characteristics is most suggestive of this condition?

<p>Pulsus parvus et tardus (C)</p> Signup and view all the answers

What is the typical auscultatory finding in aortic stenosis?

<p>Harsh systolic ejection murmur radiating to the neck (A)</p> Signup and view all the answers

Which of the following echocardiographic findings is consistent with severe aortic stenosis?

<p>Aortic valve area of 0.8 cm² (B)</p> Signup and view all the answers

In the management of asymptomatic patients with mild to moderate aortic stenosis, which of the following is generally recommended?

<p>Avoidance of strenuous activity (B)</p> Signup and view all the answers

Which type of stress test is generally CONTRAINDICATED in patients with symptomatic severe aortic stenosis?

<p>Exercise stress test (A)</p> Signup and view all the answers

For a patient with symptomatic severe aortic stenosis who is deemed a poor surgical candidate, which less invasive treatment option may be considered for symptomatic relief?

<p>Percutaneous balloon valvuloplasty (A)</p> Signup and view all the answers

Chronic aortic regurgitation leads to which type of ventricular remodeling?

<p>Eccentric hypertrophy (B)</p> Signup and view all the answers

A patient with chronic aortic regurgitation may remain asymptomatic for a prolonged period due to which compensatory mechanism?

<p>Left ventricular hypertrophy and dilation (D)</p> Signup and view all the answers

Which of the following physical exam findings is considered CLASSIC for aortic regurgitation?

<p>Bounding peripheral pulses and wide pulse pressure (C)</p> Signup and view all the answers

Which class of medications is generally contraindicated in patients with significant aortic regurgitation?

<p>Beta-blockers (A)</p> Signup and view all the answers

What is the most common cause of mitral stenosis worldwide?

<p>Rheumatic heart disease (D)</p> Signup and view all the answers

Which of the following auscultatory findings is most characteristic of mitral stenosis?

<p>Diastolic murmur with an opening snap at the apex (D)</p> Signup and view all the answers

The murmur of pulmonic regurgitation due to pulmonary hypertension (Graham Steell murmur) is best described as:

<p>High-pitched diastolic decrescendo murmur (C)</p> Signup and view all the answers

A 9-year-old child is diagnosed with acute rheumatic fever. Which of the following cardiac valves is most frequently affected in the late sequelae of this condition?

<p>Mitral valve (D)</p> Signup and view all the answers

A harsh, late-peaking systolic ejection murmur, radiating to the neck, is a characteristic auscultatory finding in which valvular heart disease?

<p>Aortic stenosis (D)</p> Signup and view all the answers

Which echocardiographic finding is consistent with severe aortic stenosis?

<p>Aortic valve area of 0.7 cm² (A)</p> Signup and view all the answers

A patient with aortic stenosis develops exertional syncope. This symptom is primarily due to:

<p>Inability to increase cardiac output with exertion (B)</p> Signup and view all the answers

In chronic aortic regurgitation, which compensatory mechanism allows patients to remain asymptomatic for a prolonged period?

<p>Left ventricular hypertrophy and dilatation (D)</p> Signup and view all the answers

What is the most common etiology of mitral stenosis worldwide?

<p>Rheumatic heart disease (B)</p> Signup and view all the answers

An opening snap followed by a diastolic rumble murmur is most characteristic of which valvular lesion?

<p>Mitral stenosis (A)</p> Signup and view all the answers

In mitral stenosis, atrial fibrillation is a common complication. What is the most significant hemodynamic consequence of atrial fibrillation in a patient with mitral stenosis?

<p>Loss of atrial contribution to ventricular filling and increased pulmonary congestion (C)</p> Signup and view all the answers

A loud, high-pitched pansystolic murmur radiating to the axilla is most characteristic of:

<p>Mitral regurgitation (C)</p> Signup and view all the answers

Myxomatous degeneration is the most common pathological finding associated with:

<p>Mitral valve prolapse (D)</p> Signup and view all the answers

In tricuspid stenosis, the diastolic murmur intensity is typically augmented by:

<p>Inspiration (C)</p> Signup and view all the answers

Which of the following non-surgical treatments is contraindicated in patients with symptomatic aortic stenosis?

<p>Vasodilators to reduce afterload (C)</p> Signup and view all the answers

A patient presents with signs and symptoms suggestive of acute rheumatic fever. According to the revised Jones criteria, what is the minimum requirement of major and minor criteria, along with evidence of preceding streptococcal infection, to diagnose acute rheumatic fever?

<p>Two major criteria or one major and two minor criteria (A)</p> Signup and view all the answers

A 74-year-old man presents with progressive dyspnea, dizziness on exertion, and no history of MI. Physical exam reveals a systolic murmur at the right upper sternal border radiating to the carotids. Which finding would support the diagnosis?

<p>Pulsus parvus et tardus (B)</p> Signup and view all the answers

In which of the following patients would surgical valve replacement be most urgent?

<p>A patient with acute AI due to endocarditis (D)</p> Signup and view all the answers

Which of the following is not a typical feature of chronic aortic regurgitation on physical exam?

<p>Systolic murmur radiating to the neck (B)</p> Signup and view all the answers

A 70-year-old man with severe AI is being managed medically. Which medication class should be avoided due to its effect on diastolic time?

<p>Beta-blockers (A)</p> Signup and view all the answers

A patient has a diastolic murmur with an opening snap, best heard in the left lateral decubitus position. Which other finding is most consistent with this diagnosis?

<p>Loud P2 and RV heave (B)</p> Signup and view all the answers

Which of the following is a surgical indication in a patient with chronic AI?

<p>EF 52%, LVESD 60 mm (B)</p> Signup and view all the answers

Which valvular disease is most likely in a patient with a mid-systolic click and a late systolic murmur at the apex that varies with position?

<p>Mitral valve prolapse (A)</p> Signup and view all the answers

A patient has a new diagnosis of mitral stenosis. Which of the following findings suggests the disease has progressed significantly?

<p>Loud P2 with RV heave (A)</p> Signup and view all the answers

A patient with dyspnea and a holosystolic murmur at the apex radiating to the axilla is diagnosed with mitral regurgitation. Which of the following is most accurate regarding acute vs chronic presentation?

<p>Acute MR has poorly tolerated LV overload (A)</p> Signup and view all the answers

A 28-year-old IV drug user presents with fever and a new murmur. JVP is elevated and a holosystolic murmur is heard at the LLSB, louder with inspiration. What is the most likely diagnosis?

<p>Tricuspid regurgitation (D)</p> Signup and view all the answers

A 72-year-old man with chronic hypertension is found to have a systolic murmur radiating to the carotids. What is the most likely cause of his valve disease?

<p>Senile calcification (D)</p> Signup and view all the answers

A 45-year-old man has a loud diastolic murmur and bounding pulses. He had a febrile illness 2 weeks ago and now has a wide pulse pressure. What is the most likely etiology?

<p>Infective endocarditis (D)</p> Signup and view all the answers

A patient is found to have mitral stenosis. Which feature helps distinguish a rheumatic etiology from other causes?

<p>Shortened, fused chordae (D)</p> Signup and view all the answers

A 65-year-old man presents with exertional dyspnea and angina. He has a systolic ejection murmur at the right upper sternal border. Which of the following is a contraindication to treadmill stress testing?

<p>Aortic valve area 0.6 cm² (B)</p> Signup and view all the answers

Which valvular lesion most often results from papillary muscle rupture following myocardial infarction?

<p>Mitral regurgitation (B)</p> Signup and view all the answers

Which of the following murmurs is always pathological and should prompt echocardiography in older adults?

<p>Diastolic decrescendo murmur (B)</p> Signup and view all the answers

A 67-year-old patient is diagnosed with severe aortic stenosis. He has no symptoms but is found to have reduced EF. What is the most appropriate next step?

<p>Refer for valve replacement (C)</p> Signup and view all the answers

Which of the following features best distinguishes tricuspid regurgitation from mitral regurgitation on physical exam?

<p>Murmur intensity increases with inspiration (C)</p> Signup and view all the answers

A patient has severe MR and is being considered for surgery. Which of the following is not a standard surgical trigger in chronic MR?

<p>Left atrial diameter 3.8 cm (B)</p> Signup and view all the answers

A 70-year-old man is found to have mild aortic stenosis on routine echo. What is the recommended management?

<p>Repeat echo in 3-5 years (C)</p> Signup and view all the answers

A patient with severe chronic aortic regurgitation has a low-pitched diastolic rumble heard at the apex. There is no mitral stenosis. What murmur is this?

<p>Austin Flint murmur (B)</p> Signup and view all the answers

Which murmur is associated with pulmonary hypertension and heard as a high-pitched early diastolic sound along the left sternal border?

<p>Graham-Steell (A)</p> Signup and view all the answers

A 70-year-old man with a mechanical aortic valve presents for follow-up. He is currently taking aspirin 81 mg daily. What is the most appropriate adjustment?

<p>Add warfarin with INR goal 2.0-3.0 (C)</p> Signup and view all the answers

Which of the following findings is least helpful in distinguishing mitral regurgitation from aortic regurgitation on auscultation?

<p>S3 presence (C)</p> Signup and view all the answers

A 74-year-old woman has mitral stenosis with a mean pressure gradient of 7 mmHg and valve area of 1.3 cm². She is asymptomatic. What is the appropriate next step?

<p>Annual follow-up with echo (A)</p> Signup and view all the answers

Which of the following is most predictive of disease severity in mitral stenosis?

<p>Murmur duration (B)</p> Signup and view all the answers

A 69-year-old patient has a systolic murmur best heard at the apex, radiating to the axilla. Which of the following would make this murmur louder?

<p>Handgrip (A)</p> Signup and view all the answers

A 65-year-old man has a crescendo-decrescendo systolic murmur at the right upper sternal border. He has normal LV function but is symptomatic with exertional dizziness. What is the most appropriate next step?

<p>Refer for TAVR (B)</p> Signup and view all the answers

Which of the following is a common complication of mitral stenosis?

<p>Atrial fibrillation (D)</p> Signup and view all the answers

A patient with mitral regurgitation is undergoing TTE. Which of the following findings indicates the need for surgical referral?

<p>EF 62%, new AF (C)</p> Signup and view all the answers

Flashcards

Rheumatic Fever

Inflammatory disease after untreated strep throat. Affects joints, heart, skin, brain.

Major Jones Criteria

Polyarthritis, carditis, subcutaneous nodules, erythema marginatum, Sydenham's chorea.

Minor Jones Criteria

Fever, arthralgia, elevated ESR/CRP, prolonged PR interval on ECG.

Rheumatic Fever Treatment

Penicillin to eradicate strep, aspirin for arthritis, heart failure management, prophylaxis with monthly benzathine penicillin IM for 5-10 years.

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Aortic Stenosis

Narrowing of the aortic valve obstructing blood flow from the LV.

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Aortic Stenosis Etiology

Calcific aortic stenosis, congenital bicuspid valve.

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Aortic Stenosis Symptoms

Angina, syncope, heart failure.

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Aortic Stenosis Murmur

Harsh systolic ejection murmur radiating to the neck.

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Aortic Stenosis Diagnosis

LVH with strain, calcified AV, high doppler gradient.

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Aortic Stenosis Treatment

Avoid strenuous activity, manage CHF, aortic valve replacement.

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Aortic Regurgitation

Incompetent aortic valve allows backflow from the aorta into the left ventricle during diastole.

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Chronic Aortic Regurgitation

Aortic dissection, age-related dilation, hypertension, Marfan's syndrome.

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Acute Aortic Regurgitation

Endocarditis, rheumatic fever, congenital bicuspid valve.

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Chronic AR Pathophysiology

AI causes volume overload, but ejection fraction is preserved until the late stages of disease.

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Aortic Regurgitation Symptoms

Usually asymptomatic, DOE, orthopnea, PND, angina.

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Aortic Regurgitation Murmur

Diastolic murmur with wide pulse pressure. The Apical impulse is diffuse, hyperdynamic and displaced inferior/laterally

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AR Physical Exam

Wide pulse pressure, bounding pulses, possible diastolic murmur.

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Aortic Regurgitation Diagnosis

EKG LVH, CXR cardiomegaly, dilated aorta.

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Medical Management Aortic Regurgitation

Vasodilators (ACE-I, nifedipine, hydralazine, or prazosin) and avoid beta blockers

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When to consider surgical intervention for Aortic Regurgitation

Aortic valve replacement if symptomatic

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Mitral Stenosis

Narrowing of mitral orifice impeding LV inflow.

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Mitral Stenosis Etiology

Rheumatic heart disease.

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Mitral Stenosis Symptoms

Dyspnea, orthopnea, PND, hemoptysis, A-fib/stroke.

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Mitral Stenosis Murmur

Low-pitched diastolic rumble with opening snap.

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Mitral Stenosis Diagnosis

EKG A-fib, RVH; CXR LA enlargement, pulmonary congestion.

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Mitral Stenosis Treatment

Treat rate and rhythm (a-fib), anticoagulation, balloon valvotomy.

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Mitral Regurgitation

Incompetent mitral valve allowing backflow from LV to LA during systole.

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Acute Mitral Regurgitation

Acute papillary muscle dysfunction from coronary ischemia.

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Chronic Mitral Regurgitation

Mitral valve prolapse, prosthetic valve failure, myxomatous degeneration.

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Mitral Regurgitation Murmur

Loud pansystolic murmur radiating to axilla.

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Mitral Regurgitation Diagnosis

EKG LA enlargement, LVH; CXR LA/LV enlargement, pulmonary congestion. Echo to see if valve is incompetent.

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Mitral Regurgitation Treatment

Aggressive CHF treatment, mitral valve repair or replacement.

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Mitral Valve Prolapse

Billowing of mitral valve leaflets into the LA during systole.

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Mitral Valve Prolapse Etiology

Myxomatous degeneration.

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Mitral Valve Prolapse

A mid-systolic click and late systolic murmur.

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Treatment for Mitral Valve Prolapse

Treatment is antiarrhythmicas, anticoags & MVR.

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Tricuspid Valve Stenosis

Usually Rheumatic Valvulitis, but also carcinoid tumor or a congenital heart disease.

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Murmurs related to the Tricuspid Valve Stenosis.

Murmur of MS best heard at apex rather than at the LSB.

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Tricuspid Valve Regurgitation

Functional to marked in RV dilations, and is often associated with Pulmonary HTN

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With the murmurs associated TR try and consider what this means.

Holosystolic plateauing blowing murmur over RV.

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Pulmonary issues and TVR

If Pulomonary HTN is present, could lead to a loud P2 if there is thrust.

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To find out if those are indeed serious issues try and ask.

Post stenotic dilation of PA requires surgury.

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What could this mean and how to differate?

You are hearing a high Basal blowing diastolic murmur and PI has similaritiies.

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Usually for all these conditions the symptoms and treatment involve.

Usually directed at the underlying cause of PHTN.

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What causes Rheumatic Fever?

A delayed sequelae of Group A beta-hemolytic streptococci infection.

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What are the Jones Criteria?

A clinical tool utilizing major and minor criteria, plus evidence of prior strep infection, to diagnose acute rheumatic fever.

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What is Aortic Stenosis (AS)?

Aortic valve narrowing restricting blood flow.

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What is Concentric LVH?

High afterload from AS leads to compensation.

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What should AS patients avoid?

Avoid strenuous intensity exercise.

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Aortic Insufficiency (AI)

Incompetent valve causing backflow into the left ventricle.

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Classic AI signs?

High-pitched, blowing decrescendo murmur, wide pulse pressure, bounding pulses.

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Critical AI treatment?

Urgent aortic valve replacement.

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What can be seen on CXR if a person has Mitral Senosis?

Left atrial enlargement & Pulmonary congestion

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What changes if any if patient has MS during lung exam and a opening of heart?

Increased respiratory rate, increased JVP and there will be crackles when lung exam is completed.

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What does severe MS mean?

The valve has become too narrow that the atrium now has an enlarged portion in space that should not be there.

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Aortic Stenosis hallmark

Slow-rising carotid pulse + systolic murmur

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Acute AI urgency

Surgical emergency due to hemodynamic instability

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AR physical exam exclusion

Diastolic murmur radiating to the neck

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AI medication to avoid

Beta-blockers prolong diastole

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Mitral stenosis consequence

Pulmonary HTN, can lead to loud P2 + RV heave

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Chronic AI Surgical Indication

Surgery indicated if EF <55% or LVESD >55 mm in severe AI

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MVP hallmark

Mid-systolic click + variable late systolic murmur

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Mitral Stenosis Progression

Advanced MS leads to pulmonary HTN → RV strain

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Acute MR

No time for LA/LV remodeling → rapid rise in pressure, pulmonary edema, collapse

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Tricuspid regurgitation

Systolic murmur that increases with inspiration

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Common Aortic Stenosis Cause

Degenerative calcification

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Infective Endocarditis

Acute AI + recent infection

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Rheumatic MS

Commissural fusion + thickened leaflets + chordal shortening

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AS contraindication

Severe AS (<1.0 cm²)

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Post-MI papillary rupture

Sudden acute MR

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Pathological Murmurs

All diastolic murmurs are abnormal

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AS Surgical Indication

Severe AS + reduced EF

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Carvallo's Sign

TR murmur ↑ with inspiration

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MR maneuver

Handgrip ↑ afterload

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Mitral Stenosis risks

LA pressure ↑ from MS → LA dilation

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Study Notes

Aortic Stenosis (AS)

  • The classic symptoms of LV outflow obstruction are heart failure, angina, and syncope, indicating advanced disease.
  • Physical exam may reveal pulsus parvus et tardus (weak/slow rising carotid pulse).
  • Severe AS (valve area <1.0 cm²) is a contraindication to treadmill stress testing due to the risk of syncope or sudden death.
  • Degenerative calcification is a common cause of AS in patients >70 years old.
  • In the absence of symptoms, avoid strenuous activity.
  • Severe AS with reduced EF is a surgical indication, even if asymptomatic.

Aortic Insufficiency (AI) or Aortic Regurgitation (AR)

  • Acute AI due to endocarditis is a surgical emergency due to hemodynamic instability. Urgent aortic valve replacement (AVR) is indicated.
  • In chronic AI, beta-blockers should be avoided as they prolong diastole and worsen aortic regurgitation.
  • Surgical intervention for chronic AI is indicated if EF < 55% or LVESD > 55 mm.
  • In chronic AR shows a diastolic murmur, Austin Flint, and bounding pulses.

Mitral Stenosis (MS)

  • Advanced MS can lead to pulmonary hypertension, RV strain, and loud P2 with RV heave.
  • Physical exam may reveal a diastolic murmur with an opening snap, best heard in the left lateral decubitus position.
  • Longer diastolic rumble duration indicates longer pressure gradient/more severe MS.

Mitral Regurgitation (MR)

  • Acute MR is poorly tolerated because there is no time for LA/LV remodeling, leading to a rapid rise in pressure, pulmonary edema, and collapse.
  • Treatment of acute MR consists of emergent valve repair or replacement.
  • A surgical trigger in severe MR is the new onset of atrial fibrillation, even with normal EF.
  • Dyspnea and a holosystolic murmur at the apex radiating to axilla is indicative of MR.
  • Increased regurgitant murmurs with handgrip.

Mitral Valve Prolapse (MVP)

  • Physical exam may reveal a mid-systolic click and a late systolic murmur, best heard at apex in LDD.

Tricuspid Regurgitation (TR)

  • IV drug use with a systolic murmur that increases with inspiration should be suspected.
  • Murmur intensity which increases with inspiration (Carvallo's sign) distinguishes TR from MR.

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