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Questions and Answers
What type of tumor does retinoblastoma encode proteins to suppress?
What type of tumor does retinoblastoma encode proteins to suppress?
- Benign tumor arising from immature neurons in the retina
- Malignant tumor arising from mature neurons in the retina
- Benign tumor arising from mature neurons in the retina
- Malignant tumor arising from immature neurons in the retina (correct)
What percentage of retinoblastoma cases are associated with a germline mutation?
What percentage of retinoblastoma cases are associated with a germline mutation?
- 40% (correct)
- 20%
- 10%
- 70%
What evidence supports the existence of tumor suppressor genes?
What evidence supports the existence of tumor suppressor genes?
- Cell fusion studies showing a tumor cell fused to a normal cell produces a tumorigenic hybrid cell
- Cell fusion studies showing a normal cell fused to a tumor cell produces a nontumorigenic hybrid cell (correct)
- Cell fusion studies showing a tumor cell fused to a normal cell produces a nontumorigenic hybrid cell
- Cell fusion studies showing a normal cell fused to a tumor cell produces a tumorigenic hybrid cell
What happens if an affected child inherits one defective Rb allele and the remaining normal Rb allele is inactivated?
What happens if an affected child inherits one defective Rb allele and the remaining normal Rb allele is inactivated?
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What is the percentage of new germline mutations in Drosophila (fruit fly) for suppressor genes?
What is the percentage of new germline mutations in Drosophila (fruit fly) for suppressor genes?
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