Retinoblastoma
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Retinoblastoma

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@OticZebra

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Questions and Answers

What type of tumor does retinoblastoma encode proteins to suppress?

  • Benign tumor arising from immature neurons in the retina
  • Malignant tumor arising from mature neurons in the retina
  • Benign tumor arising from mature neurons in the retina
  • Malignant tumor arising from immature neurons in the retina (correct)

    • What percentage of retinoblastoma cases are associated with a germline mutation?

  • 40% (correct)
  • 20%
  • 10%
  • 70%

    • What evidence supports the existence of tumor suppressor genes?

  • Cell fusion studies showing a tumor cell fused to a normal cell produces a tumorigenic hybrid cell
  • Cell fusion studies showing a normal cell fused to a tumor cell produces a nontumorigenic hybrid cell (correct)
  • Cell fusion studies showing a tumor cell fused to a normal cell produces a nontumorigenic hybrid cell
  • Cell fusion studies showing a normal cell fused to a tumor cell produces a tumorigenic hybrid cell

    • What happens if an affected child inherits one defective Rb allele and the remaining normal Rb allele is inactivated?

    <p>Development of retinoblastoma</p> Signup and view all the answers

    What is the percentage of new germline mutations in Drosophila (fruit fly) for suppressor genes?

    <p>20-30%</p> Signup and view all the answers

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