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Retinoblastoma

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Questions and Answers

What type of tumor does retinoblastoma encode proteins to suppress?

Benign tumor arising from immature neurons in the retina

Malignant tumor arising from mature neurons in the retina

Benign tumor arising from mature neurons in the retina

Malignant tumor arising from immature neurons in the retina (correct)

What percentage of retinoblastoma cases are associated with a germline mutation?

40% (correct)

20%

10%

70%

What evidence supports the existence of tumor suppressor genes?

Cell fusion studies showing a tumor cell fused to a normal cell produces a tumorigenic hybrid cell

Cell fusion studies showing a normal cell fused to a tumor cell produces a nontumorigenic hybrid cell (correct)

Cell fusion studies showing a tumor cell fused to a normal cell produces a nontumorigenic hybrid cell

Cell fusion studies showing a normal cell fused to a tumor cell produces a tumorigenic hybrid cell

What happens if an affected child inherits one defective Rb allele and the remaining normal Rb allele is inactivated?

<p>Development of retinoblastoma</p> Signup and view all the answers

What is the percentage of new germline mutations in Drosophila (fruit fly) for suppressor genes?

<p>20-30%</p> Signup and view all the answers

Retinoblastoma

Choose a study mode

Podcast

Questions and Answers

What type of tumor does retinoblastoma encode proteins to suppress?

What percentage of retinoblastoma cases are associated with a germline mutation?

What evidence supports the existence of tumor suppressor genes?

What happens if an affected child inherits one defective Rb allele and the remaining normal Rb allele is inactivated?

What is the percentage of new germline mutations in Drosophila (fruit fly) for suppressor genes?

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