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Questions and Answers
What is the primary function of the mucus-producing cells in the upper respiratory tract?
What is the primary function of the mucus-producing cells in the upper respiratory tract?
Which structure provides support in the middle respiratory tract?
Which structure provides support in the middle respiratory tract?
What mixture is produced by the alveoli to prevent them from collapsing?
What mixture is produced by the alveoli to prevent them from collapsing?
How many lobes does the right lung have?
How many lobes does the right lung have?
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What is the role of the pleura covering the lungs?
What is the role of the pleura covering the lungs?
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What might be necessary for treating chronic bronchitis if a bacterial infection is present?
What might be necessary for treating chronic bronchitis if a bacterial infection is present?
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Which of the following is NOT a common symptom of emphysema?
Which of the following is NOT a common symptom of emphysema?
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What is a significant consequence of the destruction of alveoli in emphysema?
What is a significant consequence of the destruction of alveoli in emphysema?
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What is the primary function of the lungs?
What is the primary function of the lungs?
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Which of the following conditions is characterized by inflammation of the tracheobronchial tree?
Which of the following conditions is characterized by inflammation of the tracheobronchial tree?
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Which of the following diagnostic tests is used to identify hyperinflation in emphysema?
Which of the following diagnostic tests is used to identify hyperinflation in emphysema?
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What triggers asthma symptoms in hypersensitive airways?
What triggers asthma symptoms in hypersensitive airways?
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What triggers a common cold?
What triggers a common cold?
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What is dyspnea?
What is dyspnea?
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Which bacterial infection is commonly associated with pneumonia?
Which bacterial infection is commonly associated with pneumonia?
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What condition can result from a viral upper respiratory infection spreading to the middle ear?
What condition can result from a viral upper respiratory infection spreading to the middle ear?
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What are bronchial arteries responsible for supplying?
What are bronchial arteries responsible for supplying?
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What is the medical term for coughing out blood?
What is the medical term for coughing out blood?
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What percentage of deaths did cardiovascular disease account for in 2010?
What percentage of deaths did cardiovascular disease account for in 2010?
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Which of the following conditions was reported as the second most common non-fatal condition in the UAE?
Which of the following conditions was reported as the second most common non-fatal condition in the UAE?
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Which gas makes up the largest percentage of air?
Which gas makes up the largest percentage of air?
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What percentage of air is oxygen?
What percentage of air is oxygen?
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What prevalent factor increases the risk of respiratory disorders in the UAE population?
What prevalent factor increases the risk of respiratory disorders in the UAE population?
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By 2020, what was projected regarding the incidence of all cancers?
By 2020, what was projected regarding the incidence of all cancers?
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What role do the lungs primarily serve in the human body?
What role do the lungs primarily serve in the human body?
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During which year was the significant health issue analysis performed on the United Arab Emirates?
During which year was the significant health issue analysis performed on the United Arab Emirates?
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What is a common cause of lung cancer in most cases?
What is a common cause of lung cancer in most cases?
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Which hormone is associated with the syndrome of inappropriate ADH secretion in lung cancer?
Which hormone is associated with the syndrome of inappropriate ADH secretion in lung cancer?
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What pulmonary function symptom is most commonly associated with asthma?
What pulmonary function symptom is most commonly associated with asthma?
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Which of the following is NOT a sign or symptom of lung cancer?
Which of the following is NOT a sign or symptom of lung cancer?
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What is considered a severe complication of asthma?
What is considered a severe complication of asthma?
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At what age is lung cancer most commonly rare?
At what age is lung cancer most commonly rare?
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What percentage of lung cancers is classified as adenocarcinoma?
What percentage of lung cancers is classified as adenocarcinoma?
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Which diagnostic test is NOT typically used for lung cancer detection?
Which diagnostic test is NOT typically used for lung cancer detection?
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Which of the following management techniques is commonly used for lung cancer?
Which of the following management techniques is commonly used for lung cancer?
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What role does the bat play in relation to SARS-CoV-2?
What role does the bat play in relation to SARS-CoV-2?
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What is the most common way COVID-19 spreads?
What is the most common way COVID-19 spreads?
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Which of the following is NOT a less common symptom of COVID-19?
Which of the following is NOT a less common symptom of COVID-19?
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Which diagnostic method is preferred for the direct diagnosis of COVID-19?
Which diagnostic method is preferred for the direct diagnosis of COVID-19?
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Which prevention measure is recommended for reducing COVID-19 transmission?
Which prevention measure is recommended for reducing COVID-19 transmission?
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What is a serious symptom of COVID-19?
What is a serious symptom of COVID-19?
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How long does it typically take for symptoms of COVID-19 to show after infection?
How long does it typically take for symptoms of COVID-19 to show after infection?
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What does serologic testing for SARS-CoV-2 assess?
What does serologic testing for SARS-CoV-2 assess?
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Which of the following is NOT a recommendation for preventing COVID-19?
Which of the following is NOT a recommendation for preventing COVID-19?
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Study Notes
Respiratory Disorders
- Respiratory disorders are a significant health concern in the UAE, often the second most common non-life-threatening condition.
- In 2010, respiratory infections accounted for nearly 15% of all healthcare encounters.
- The high risk for respiratory issues in the UAE is due to increased urbanization, reliance on motorized transport, traffic congestion, dust storms and rapid expansion of construction.
- Some common respiratory disorders are presented in the following subsections.
Common Respiratory Infections
- Common Cold: Viral infection of the nasopharynx.
- Pharyngitis: Caused by viruses or Streptococcus (strep throat).
- Otitis Media: Viral upper respiratory infections (URIs) spreading to the middle ear, causing edema and Eustachian tube obstruction resulting in fluid accumulation. Can become superinfected with bacteria.
Lower Respiratory Infections
- Pneumonia: Acute infection of the lungs by bacteria (like Streptococcus, Haemophilus influenzae, and Staphylococcus), or less commonly viruses, fungi, protozoa or parasites.
- Bronchitis: Inflammation of the tracheobronchial tree. Acute bronchitis is typically viral; bacterial infection may also occur.
- Tuberculosis: Acute or chronic bacterial infection caused by Mycobacterium tuberculosis, leading to granulomas, fibrosis and cavitation.
Pneumonia - Terminology
- Dyspnea: Shortness of breath.
- Tachypnea: Rapid breathing.
- Expectoration: Coughing out phlegm ("wet cough").
- Prostration: Weakness, fatigue, apathy.
- Hemoptysis: Blood in the sputum.
- Debilitated: Weak, chronically ill.
- Virulent: A strong pathogen.
Pneumonia - Pathogenesis
- Pathogens can reach the lungs via inhalation (breathing in germs).
- Aspiration (breathing in germs with fluid), including infected secretions, or infected gastric juices, foods or drinks.
- Hematogenous spread - transfer through blood.
Pneumonia - Pathology
- Exudate results from pathogenic invasion.
- Exudate accumulates in the airways and alveoli;
- Air spaces become consolidated (denser than air) which is visible on an X-ray.
Pneumonia - Signs and Symptoms
- Systemic signs of infection (e.g., high fever, chills, prostration).
- Local infection signs (e.g., secretion of mucus, cough, chest pain).
- Airways obstruction (e.g., dyspnea, tachypnea).
- Tissue inflammation and destruction (e.g., exudate causing tissue destruction and bleeding, purulent mucus, rusty sputum, hemoptysis).
Diagnostic Tests (Pneumonia)
- Chest X-ray: Identify high exudate levels.
- Sputum gram stain & culture: Identifies bacteria or virus.
- Blood tests: High white blood cell count (WBC) in bacterial pneumonia.
Pneumonia - Complications
- Pleuritis: Inflammation of the pleural surfaces with pus buildup.
- Abscess: Destruction and dilation of bronchial walls due to pus.
- Chronic Lung Disease: Lung tissue destruction causing fibrosis (honeycomb lungs).
Pneumonia - Treatment
- The primary goal is antibiotic treatment to destroy the bacterial cause along with supportive care for lung function.
- Antibiotics: Targeted for specific bacteria
- Respiratory Support: Humidified oxygen, Mechanical ventilation (for severe cases), High calorie diet for recovery, High fluid intake
- Rest: Bed rest
- Environment: Quiet, calm environment. Promoting deep breathing and coughing with the use of analgesics for pain relief.
Pulmonary Tuberculosis (TB)
- A chronic infectious disease caused by Mycobacterium tuberculosis
- Types of TB -Pulmonary TB – Tuberculous pneumonia -Extrapulmonary TB
- Different methods of spread include lymphatic, blood, and airways; swallowed into the GI tract.
Pulmonary Tuberculosis (TB) - Signs & Symptoms
- Low-grade fever.
- Dry cough (initially).
- Anorexia (loss of appetite).
- Night sweats.
- Weight loss.
- Dyspnea & hemoptysis (later stages)
Pulmonary Tuberculosis (TB) - Tests and Investigations
- CXR: Chest X-ray
- Chest CT Scan: Detailed imaging.
- Sputum Exam: Test for Mycobacterium tuberculosis.
- Tuberculin Test (skin test): Not fully conclusive.
- Immunization – BCG vaccine: Prevention method.
Pulmonary Tuberculosis (TB) - Treatment
- Multiple drugs including Isoniazid (INH), Rifampin, Ethambutol and Pyrazinamide
- Long-term treatment (typically 6 months to 2 years).
- Resistant TB forms are challenging to treat.
Chronic Obstructive Lung Disease (COPD)
- Largely a consequence of smoking , with exacerbations and remissions.
- Includes:
-Chronic Bronchitis: Productive cough for 3 months of the year for 2 or more consecutive years
- Emphysema: Abnormal permanent enlargement of alveoli and destruction of alveolar walls; without obvious fibrosis.
Chronic Bronchitis - Signs and Symptoms
- Productive cough for at least 3 months of the year for 2 or more consecutive years
- Hyperactivity of mucus glands that causes inflammation and narrowing of airways
- Factors such as smoking, air pollution, cold climates are possible causes
- May develop into pneumonia
Chronic Bronchitis - Treatment
- Diagnostic Tests: Physical exam, X-ray (CXR), and sputum culture
- Treatment: Antibiotics (if bacterial infections are involved) and physiotherapy for better expectoration.
Emphysema - Signs and Symptoms
- Chronic cough
- Dyspnea
- Orthopnea
- Tachypnea
- COPD exacerbations (acute) may lead to a quickening of symptoms and include respiratory distress, sputum production and worsening cough
Emphysema - Pathophysiology
- Bronchoconstriction: Airways obstruction; sputum production; cough
- Destruction of alveoli: Impaired gas exchange; difficult exhalation.
- Hyperinflation of lungs
Emphysema - Treatment
- Diagnostic tests: CXR to show hyperinflation, Pulmonary function tests
- Management: Treat symptoms. Stop smoking (symptoms are likely to continue.)
Asthma
- Airways obstruction (bronchoconstriction) in response to allergens or stimuli (e.g. plant pollens, chemicals, exercise, psychological stress, bronchial infection, aspirin sensitivity).
Asthma - Signs & Symptoms
- Symptoms often begin before age 10.
- Wheezing (due to bronchospasm), dyspnea, cough
Asthma - Management
- Treat symptoms with bronchodilators (inhaler).
- Status Asthmaticus is serious; repeated severe bronchospasm needing urgent medical intervention.
Lung Cancer
- Malignant tumor growth in bronchial tissue or lung.
- Common cause is cigarette smoking.
- Lung cancer is rare before age 40.
- Some lung cancers produce hormones (paraneoplastic syndromes), which can have varied clinical effects.
Lung Cancer - Signs & Symptoms
- Cough
- Wheezing
- Shortness of breath
- Hemoptysis
- Chest pain
- Hoarseness
- Weight loss
- Dysphagia (difficulty swallowing, due to tumor compressing the esophagus).
Lung Cancer - Diagnosis
- Diagnostic tests: Chest X-ray (CXR), CT scan, MRI, Tumor biopsy (possibly including bronchoscopy)
- Classification by microscopic appearance: Adenocarcinoma, Squamous cell carcinoma, Large-cell carcinoma, Small-cell carcinoma, and carcinoids.
Lung Cancer - Management
- Lung cancer management is often challenging, with limited effective treatment options in many cases.
- Treatment methods : Surgery, Radiation, Chemotherapy.
- Metastasis (spread to other sites) is a major complication.
COVID-19
- Coronavirus disease.
- Primarily spread by airborne particles from an infected person, such as when they cough, sneeze, speak, or breathe.
- Impacts vary significantly, with some individuals experiencing mild symptoms (frequently managing at home) and others needing hospitalization.
- Treatment and prevention strategies include vaccination, social distancing, mask wearing, and managing mild cases at home; for serious symptoms, seeking prompt medical support.
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Description
Test your knowledge on the key functions and structures of the respiratory system. This quiz covers topics from lung functions, diseases, to symptoms associated with respiratory conditions. Perfect for students studying human anatomy or health sciences.