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Questions and Answers
Which of the following statements accurately describes the function of the intrinsic muscles of the larynx?
Which of the following statements accurately describes the function of the intrinsic muscles of the larynx?
What is the primary function of the cartilage rings in the trachea?
What is the primary function of the cartilage rings in the trachea?
Which of the following structures is NOT involved in the process of swallowing?
Which of the following structures is NOT involved in the process of swallowing?
What is the primary function of the carina?
What is the primary function of the carina?
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What type of epithelium lines the trachea?
What type of epithelium lines the trachea?
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What is the primary function of the muscles in the posterior wall of the trachea?
What is the primary function of the muscles in the posterior wall of the trachea?
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What is the role of the seromucous glands in the trachea?
What is the role of the seromucous glands in the trachea?
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Where does the trachea extend from and to?
Where does the trachea extend from and to?
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What process describes the movement of O2 from the lungs to the blood?
What process describes the movement of O2 from the lungs to the blood?
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Which gas law states that individual gases in a mixture exert pressure proportional to their abundance?
Which gas law states that individual gases in a mixture exert pressure proportional to their abundance?
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What term describes the movement of O2 from the blood to the cell interior?
What term describes the movement of O2 from the blood to the cell interior?
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According to Henry's Law, what factor determines the amount of gas in solution?
According to Henry's Law, what factor determines the amount of gas in solution?
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Which of the following describes the physiological movement of air into and out of the lungs?
Which of the following describes the physiological movement of air into and out of the lungs?
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What can control the respiratory rate according to various stimuli?
What can control the respiratory rate according to various stimuli?
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How does aging affect the respiratory system?
How does aging affect the respiratory system?
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What is the primary function of T cells in the immune response?
What is the primary function of T cells in the immune response?
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Which of the following correctly describes B cells?
Which of the following correctly describes B cells?
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Which center is indicated to play a role in controlling respiration?
Which center is indicated to play a role in controlling respiration?
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What distinguishes primary lymphatic organs from secondary lymphatic organs?
What distinguishes primary lymphatic organs from secondary lymphatic organs?
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What effect does the deterioration of elastic tissue have on the lungs?
What effect does the deterioration of elastic tissue have on the lungs?
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Which of the following actions can lead to hyperventilation?
Which of the following actions can lead to hyperventilation?
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Which type of cell primarily acts to phagocytize foreign substances?
Which type of cell primarily acts to phagocytize foreign substances?
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What role do dendritic cells play in the immune response?
What role do dendritic cells play in the immune response?
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What may happen when voluntary control of respiration is exerted?
What may happen when voluntary control of respiration is exerted?
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What is a common respiratory change that occurs with age?
What is a common respiratory change that occurs with age?
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Which system is primarily influenced by emotional states affecting respiration?
Which system is primarily influenced by emotional states affecting respiration?
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What is the primary function of complement proteins in the immune response?
What is the primary function of complement proteins in the immune response?
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Which of the following is NOT an iron-binding protein?
Which of the following is NOT an iron-binding protein?
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What is the role of antimicrobial proteins (AMPs) in the immune system?
What is the role of antimicrobial proteins (AMPs) in the immune system?
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What occurs during the chemotaxis phase of phagocytosis?
What occurs during the chemotaxis phase of phagocytosis?
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Which of the following is a characteristic of inflammation?
Which of the following is a characteristic of inflammation?
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What is the primary role of phagocytes during the inflammatory response?
What is the primary role of phagocytes during the inflammatory response?
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What substance increases the permeability of blood vessels during inflammation?
What substance increases the permeability of blood vessels during inflammation?
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During phagocytosis, which step follows adherence to the microbe?
During phagocytosis, which step follows adherence to the microbe?
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Which cell type is classified as a Natural Killer (NK) cell?
Which cell type is classified as a Natural Killer (NK) cell?
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What is a common characteristic of the five steps in phagocytosis?
What is a common characteristic of the five steps in phagocytosis?
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Which structures are part of the upper respiratory tract?
Which structures are part of the upper respiratory tract?
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What function is not associated with the conducting zone of the respiratory system?
What function is not associated with the conducting zone of the respiratory system?
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Which area is primarily identified as the site of gas exchange?
Which area is primarily identified as the site of gas exchange?
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Which of the following structures is part of the lower respiratory tract?
Which of the following structures is part of the lower respiratory tract?
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What is the main role of the respiratory zone?
What is the main role of the respiratory zone?
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Which of the following structures is NOT included in the conducting zone?
Which of the following structures is NOT included in the conducting zone?
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Which component of the respiratory system is primarily responsible for filtering the air?
Which component of the respiratory system is primarily responsible for filtering the air?
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Which sequence correctly describes the flow of air through the respiratory system?
Which sequence correctly describes the flow of air through the respiratory system?
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Flashcards
Upper Respiratory Tract
Upper Respiratory Tract
Includes the nose, pharynx, nasal cavity, and paranasal sinuses.
Lower Respiratory Tract
Lower Respiratory Tract
Includes the larynx, trachea, bronchi, bronchioles, and alveoli.
Conducting Zone
Conducting Zone
Structures that transport air but do not exchange gases.
Respiratory Zone
Respiratory Zone
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Alveoli
Alveoli
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Gas Exchange
Gas Exchange
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Function of Respiratory System
Function of Respiratory System
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Regulation of Respiration
Regulation of Respiration
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Pulmonary ventilation
Pulmonary ventilation
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External respiration
External respiration
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Gas transport
Gas transport
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Internal respiration
Internal respiration
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Dalton's Law
Dalton's Law
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Laryngeal Musculature
Laryngeal Musculature
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Epiglottis Function
Epiglottis Function
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Trachea Structure
Trachea Structure
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C-shaped Cartilage
C-shaped Cartilage
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Smooth Muscle Role
Smooth Muscle Role
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Goblet Cells
Goblet Cells
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Carina
Carina
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Primary Bronchi Division
Primary Bronchi Division
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Lymphocytes
Lymphocytes
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T cells
T cells
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B cells
B cells
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Antigen
Antigen
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Primary vs Secondary lymphatic organs
Primary vs Secondary lymphatic organs
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Hyperventilation
Hyperventilation
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Voluntary Control of Respiration
Voluntary Control of Respiration
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Effect of Emotions on Breathing
Effect of Emotions on Breathing
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Aging and Respiratory Efficiency
Aging and Respiratory Efficiency
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Lung Compliance
Lung Compliance
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Vital Capacity
Vital Capacity
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Chest Movement Restrictions
Chest Movement Restrictions
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Emphysema
Emphysema
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Complement
Complement
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Iron-binding proteins
Iron-binding proteins
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Antimicrobial proteins (AMPs)
Antimicrobial proteins (AMPs)
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Natural Killer (NK) cells
Natural Killer (NK) cells
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Phagocytes
Phagocytes
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Chemotaxis
Chemotaxis
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Phagocytosis steps
Phagocytosis steps
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Inflammation
Inflammation
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Vasodilation
Vasodilation
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Emigration of phagocytes
Emigration of phagocytes
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Study Notes
Respiratory System
- The respiratory system is divided into upper and lower respiratory tracts.
- The upper respiratory tract includes the nose, pharynx, nasal cavity, and paranasal sinuses
- The lower respiratory tract includes the larynx, trachea, bronchi, bronchioles, and alveoli
- The respiratory system can also be separated into a conducting zone and a respiratory zone.
- The conducting zone transports air but plays no role in gas exchange.
- It includes nasal cavity, nasopharynx, oropharynx, laryngopharynx, larynx, trachea, bronchi, and all bronchioles except for respiratory bronchioles.
- These structures are involved in transporting, filtering, humidifying, and warming air.
- The respiratory zone involves structures where O2 and CO2 exchange occurs, sites for gas exchange are alveoli.
- All respiratory zone structures contain alveoli and include: respiratory bronchioles, alveolar ducts, and alveolar sacs.
- The respiratory system includes the trachea, which is inferior to the cricoid cartilage, extends from the larynx to the mediastinum, divides into left and right primary bronchi at the fifth thoracic vertebra, and is lined by pseudostratified epithelium associated with goblet cells.
Learning Outcomes
- Understand the anatomy of the respiratory system
- Understand the function of the respiratory system
- Understand the process of gas exchange and gas transport
- Understand the regulation of respiration
The Pharynx
- Shared by the digestive and respiratory systems.
- Divided into three sections:
- Nasopharynx (pseudostratified columnar): Superior portion, enclosed by uvula during swallowing
- Oropharynx (Stratified squamous): Continuous with the oral cavity
- Laryngopharynx: From tip of epiglottis until esophagus
The Larynx
- Air passes through the glottis on the way to the lungs (C4-C6)
- The larynx protects the glottis (pathway).
- Nine cartilages form the larynx.
- Three large cartilages (thyroid, cricoid, and epiglottis)
- Six paired cartilages (cuneiform, corniculate, and arytenoids)
- Arytenoid cartilages change vocal cord position and tension.
Vocal Cords
- Primary source of voice production.
- Two pairs of ligaments at the thyroid cartilage extending posteriorly to the arytenoid cartilage.
- Superior ligaments (vestibular folds - false vocal cords).
- Inferior ligaments (true vocal cords).
- Controlled by the posterior and lateral cricoarytenoid muscles.
- Moving air through vocal cords causes vibration, producing sound. Male voices are lower due to thicker vocal folds.
Pulmonary Ventilation
- The physical movement of air into and out of the lungs. Depends on Boyle's law.
- Movement of air depends upon Boyle's Law (pressure and volume inverse relationship), with volume changes creating pressure changes.
- Volume depends on the movement of the diaphragm and ribs.
- Pressure and airflow in the lungs are regulated for breathing in and breathing out.
Respiration
- Respiration is associated with four processes: pulmonary ventilation, external respiration, gas transport, and internal respiration.
- Pulmonary ventilation: The movement of air in and out of the lungs
- External respiration: The movement of oxygen from the lungs to the blood and carbon dioxide from the blood to the lungs.
- Gas transport: The mechanisms by which oxygen and carbon dioxide are moved through the blood.
- Internal respiration: The movement of oxygen from the blood to the cell interior and carbon dioxide from the cell interior to the blood.
Gas Laws in Respiration
- Dalton's law: Individual gases in a mixture exert pressure proportional to their abundance.
- Henry's law: The amount of gas in solution is directly proportional to its partial pressure.
Respiratory Capacity
- Various measures of lung volumes
- (Tidal Volume, Inspiratory Reserve Volume, Expiratory Reserve Volume, Residual Volume)
- Various measures of lung volumes - Capacity (Inspiratory capacity, Functional Residual Capacity, Vital Capacity, Total Lung Capacity)
Aging and the Respiratory System
- The efficiency of the respiratory system decreases with age due to deteriorating elastic tissues, which leads to lower lung compliance and vital capacity and restricted chest movements due to arthritic changes.
- Some degree of emphysema normally occurs during aging.
Bronchi
- The trachea divides into two main bronchi
- The right main bronchus is wider, shorter, and more vertical than the left. This makes it more susceptible to obstruction by foreign objects.
- The bronchi are lined with pseudostratified columnar epithelium supported by C-shaped cartilage.
- Air reaching the bronchi is filtered, warmed, and humidified.
Bronchial Tree
- Each main bronchus divides into lobar bronchi (secondary bronchi) and further into segmental bronchi (tertiary bronchi).
- Right lung contains three lobar bronchi and left lung contains two.
Bronchioles
- Terminal bronchioles are the last bronchioles without alveoli.
- Respiratory bronchioles are bronchioles with alveoli
- Cartilage in the walls decreases while smooth muscle increases with branching.
- Relaxation and contraction of smooth muscle control the diameter of the airways.
The Lungs
- Lungs are separated by fissures-right lung - 3 lobes
- Left lung - 2 lobes.
- Concavity on the medial surface = cardiac notch
Lung Cells
- Alveolar cells (Pneumocytes type 1) cells line the alveolar surface.
- Septal cells (Pneumocytes type 2) cells secrete surfactant, a lipid-rich material.
- Alveolar macrophages destroy any foreign bodies.
Pleural Membranes and Cavities
- Pleura is serous membrane lining the pleural cavity for each lung.
- Parietal pleura attaches to the chest wall.
- Visceral pleura adheres to the surface of the lungs.
- Pleural fluid fills the area between the pleura.
- Pleural fluid reduces friction between visceral and parietal pleura.
Conducting Zone
- Structures that transport air but play no role in gas exchange.
- Includes nasal cavity, nasopharynx, oropharynx, laryngopharynx, larynx, trachea, bronchi, and bronchioles except for respiratory bronchioles.
- Structures in the conducting zone are responsible for filtering, warming, and humidifying the inhaled air.
Respiratory Zone
- Respiratory zone structures are located where the gas exchange between air and blood occurs.
- Alveoli are known as the sites of gas exchange.
- Respiratory zone includes respiratory bronchioles, alveolar ducts, and alveolar sacs.
Lymphatic System
- The lymphatic system consists of lymph, lymph vessels, structures, and organs containing lymphatic tissue and red bone marrow.
- Its functions drain excess interstitial fluid, transport dietary lipids, and carry out our immune responses.
- Lymphatic vessels are closed at one end and resemble veins in structure but have more valves.
- Lymphatic vessels collect excess interstitial fluid, return proteins to blood, and transport lipids.
- Lymphatic vessels travel to lymph nodes.
- Lymphoid organs with masses of B and T cells include the thymus, lymph nodes, spleen and lymphatic nodules.
Lymphatic Capillaries
- Lymphatic capillaries are slightly larger than blood capillaries.
- Permit interstitial fluid to flow into blood vessels but not out.
- Anchoring filaments pull openings wider when interstitial fluid accumulates.
Lymph Trunks and Ducts
- Structures formed when lymph vessels unite are called lymph trunks
- Principal trunks are the lumbar, intestinal, bronchomediastinal, subclavian, and jugular trunks.
- The main channels are the thoracic duct and right lymphatic duct.
Lymphoid Cells
- Lymphocytes are the main cells involved in the immune response. Two main varieties of lymphocytes are T Cells and B Cells. Both types protect the body against antigens.
Lymphoid Tissues and Organs
- Lymphoid tissue is classified into two groups depending on function: Primary Lymphoid Organs and Secondary Lymphoid Organs
- Primary lymphoid organs where stem cells divide to become immune competent. Red bone marrow and thymus.
- Secondary lymphoid organs where most immune responses occur. Lymph nodes, spleen, and lymphatic nodules.
Lymphoid Organs
- Tonsils, located in the pharyngeal region
- Thymus, located in the thorax, most active during youth.
- Spleen, curves around the left side of the stomach.
- Peyer's patches, located in the intestine.
- Appendix.
Thymus
- Thymic lobes contain an outer cortex and inner medulla.
- Cortex contains densely packed lymphocytes and scattered macrophages.
- Medulla contains fewer lymphocytes and thymic (Hassall's) corpuscles.
Lymph Nodes
- Located along lymphatic vessels, scattered throughout the body.
- Stroma consists of capsule, trabeculae, reticular fibers, and fibroblasts.
- Parenchyma - the outer cortex are aggregates of B cells (lymphatic nodules or follicles).
- Plasma B cells and memory B cells form in the outer cortex, while the inner cortex mainly contains T cells and dendritic cells.
- B cells, plasma cells, and macrophages are in the medulla
Spleen
- Largest mass of lymphatic tissue in the body, has a capsule.
- Stroma consists of capsule, trabeculae, reticular fibers and fibroblasts
- Parenchyma - White pulp is lymphatic tissue with lymphocytes and macrophages.
- B cells and T cells carry out immune function
- Red Pulp is blood-filled venous sinuses and splenic cords containing red blood cells, macrophages, lymphocytes, plasma cells and granulocytes.
Lymphatic Nodules
- Not surrounded by a capsule.
- Scattered throughout the lamina propria of mucous membranes — GI, Urinary, Reproductive tracts, and in the respiratory tract.
- Often small and solitary, but sometimes larger, like tonsils, Peyer's patches and appendix.
Immune System
- Innate: Immunity present at birth, no specific recognition of antigens, 1st and 2nd lines of defense
- Adaptive: Immunity developed after birth, distinguishes foreign antigens, includes specificity and memory
- First line of defenses include Skin and Mucous Membranes
- Second line of defenses include Phagocytic leukocytes, Antimicrobial proteins, and Fever
- Third line of defenses include Lymphocytes and Antibodies
Immune Actions
- Filtration: Macrophages destroys microorganisms and debris within the immune system
- Immune system activation: Monitors for antigens and mounts an attack against them.
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Description
Test your knowledge on the intrinsic muscles of the larynx, the function of cartilage rings in the trachea, and the process of gas exchange. This quiz covers important concepts related to the anatomy and physiology of the respiratory system. Check your understanding of lung mechanics and the roles of various structures in breathing.