Podcast
Questions and Answers
What is the primary purpose of controlling breathing?
What is the primary purpose of controlling breathing?
- To increase the rate of carbon dioxide production
- To ensure maximum carbon dioxide levels in the blood
- To maximize oxygen saturation of haemoglobin and minimize work of breathing (correct)
- To allow for reflex actions such as coughing
What occurs to CO2 levels and pH when the ventilation rate (V̇E) is halved?
What occurs to CO2 levels and pH when the ventilation rate (V̇E) is halved?
- CO2 levels decrease, causing pH to rise
- CO2 levels increase, causing pH to fall (correct)
- CO2 levels fluctuate but do not significantly affect pH
- CO2 levels remain stable, with no effect on pH
Which neural respiratory centre is primarily responsible for automatic control of breathing?
Which neural respiratory centre is primarily responsible for automatic control of breathing?
- Thalamus and hypothalamus
- Cerebral cortex
- Spinal cord
- Medulla oblongata and pons (correct)
Which type of receptor is primarily responsible for the protective reflex against lung over-inflation?
Which type of receptor is primarily responsible for the protective reflex against lung over-inflation?
Which response is NOT initiated by cough receptors found in the upper airways?
Which response is NOT initiated by cough receptors found in the upper airways?
What is the main characteristic of COPD?
What is the main characteristic of COPD?
Which pressure is negative during normal resting inspiration?
Which pressure is negative during normal resting inspiration?
What does lung compliance refer to?
What does lung compliance refer to?
Asthma attacks are primarily associated with which mechanism?
Asthma attacks are primarily associated with which mechanism?
What is the primary risk factor for developing COPD?
What is the primary risk factor for developing COPD?
How does gas exchange occur in the lungs?
How does gas exchange occur in the lungs?
What is the primary consequence of hypercapnia?
What is the primary consequence of hypercapnia?
What is the primary action that fulfills the main function of the lungs?
What is the primary action that fulfills the main function of the lungs?
What patient demographic is most affected by asthma in the UK?
What patient demographic is most affected by asthma in the UK?
Which structure is NOT part of the upper respiratory tract?
Which structure is NOT part of the upper respiratory tract?
How many lobes does the right lung have compared to the left lung?
How many lobes does the right lung have compared to the left lung?
At what generation number does the respiratory zone begin?
At what generation number does the respiratory zone begin?
Which of the following correctly describes the conducting zone of the respiratory system?
Which of the following correctly describes the conducting zone of the respiratory system?
What is the normal atmospheric pressure at sea level?
What is the normal atmospheric pressure at sea level?
Which gas is primarily removed from the tissues by the lungs?
Which gas is primarily removed from the tissues by the lungs?
What structure terminates the bronchial tree?
What structure terminates the bronchial tree?
Flashcards
Control of Breathing
Control of Breathing
The process that governs how much we breathe, ensuring enough oxygen to maintain proper blood saturation while minimizing breathing effort. It also maintains a balanced level of carbon dioxide in the blood, crucial for blood's pH.
Neural Respiratory Centres
Neural Respiratory Centres
The brain regions responsible for the automatic control of breathing, located in the medulla oblongata and pons of the brainstem.
Peripheral Receptors
Peripheral Receptors
Specialized sensory cells found in the airways and lungs, triggering responses like coughing, bronchoconstriction, or mucus release. These receptors are activated by irritants or excessive stretching.
Cough Receptors
Cough Receptors
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Stretch Receptors
Stretch Receptors
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Partial Pressure (P)
Partial Pressure (P)
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Pleural Pressure (Ppl)
Pleural Pressure (Ppl)
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Alveolar Pressure (Palv)
Alveolar Pressure (Palv)
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Lung Compliance (CL)
Lung Compliance (CL)
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Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD)
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Asthma
Asthma
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Gas Exchange
Gas Exchange
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Passive Diffusion
Passive Diffusion
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What is the main function of the lungs?
What is the main function of the lungs?
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What is internal respiration?
What is internal respiration?
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What structures make up the upper respiratory tract?
What structures make up the upper respiratory tract?
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What structures make up the lower respiratory tract?
What structures make up the lower respiratory tract?
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How many lobes does each lung have?
How many lobes does each lung have?
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How are the bronchial branches organized?
How are the bronchial branches organized?
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Where does the respiratory zone begin?
Where does the respiratory zone begin?
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What is the conducting zone?
What is the conducting zone?
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Study Notes
Respiratory System Overview
- The respiratory system's main function is providing oxygen to tissues and removing carbon dioxide.
- It includes the mechanics of breathing, gas exchange, and breathing control.
- The process involves bringing oxygen into the lungs and removing carbon dioxide from the body.
Composition of Air
- Nitrogen makes up the largest portion of the atmosphere (approximately 78.06%).
- Oxygen constitutes about 20.98%.
- Carbon dioxide is present in a small amount (approximately 0.04%).
- Helium and argon make up the remaining percentage.
Organization of the Respiratory System
- The respiratory system is divided into upper and lower respiratory tracts.
- The upper respiratory tract includes the nasal cavity, pharynx, and larynx.
- The lower respiratory tract involves the trachea, bronchi, and bronchial tree which terminates in the alveoli.
Lung Lobes
- The right lung has three lobes.
- The left lung has two lobes.
- The space taken by the pericardium for the heart accounts for the difference.
Lung Structure - Generation Numbers
- The branching sequence of the bronchial tree has a generation number.
- The generation number 1 represents where the trachea splits into two main bronchi.
- The final generation number is approximately 23.
Lung Volumes and Capacities
- Lung volumes indicate the amount of air moved in and out of the lungs.
- Lung capacities encompass various combinations of lung volumes and are used to determine a person's lung function.
- Common lung volumes include tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume.
- Common lung capacities include total lung capacity, vital capacity, inspiratory capacity, and functional residual capacity.
- These are measured using a spirometer.
Mechanics of Pulmonary Ventilation
- Atmospheric pressure at sea level is normally 101.325 kPa (760 mmHg) or 1 atm.
- The pressure exerted by a gas is the partial pressure.
- Pleural pressure is the pressure in the pleural space between visceral and parietal pleurae.
- Alveolar pressure is the pressure within the alveoli.
- The extent of lung expansion per unit of pressure is lung compliance.
Control of Breathing
- Control of breathing ensures sufficient oxygen saturation of hemoglobin and efficient work of breathing, with minimal effort.
- Adjustments in breathing control mechanisms regulate carbon dioxide levels.
- Breathing control can be modified to accommodate situations like blowing, holding breath, or speaking activities..
- Peripheral receptors (located in the airways and lungs) are part of the feedback mechanism.
- Neural centers in the brainstem (medulla oblongata, and pons) are responsible for maintaining automatic breathing.
Respiratory Diseases
- Respiratory diseases are classified into obstructive and restrictive diseases.
- Obstructive disorders, such as COPD, involve constriction of airways and resistance to airflow.
- Restrictive diseases result in decreased functional volume of the lungs.
- Examples of respiratory diseases are COPD, asthma.
Gas Exchange and Transport
- Breathing involves air entering and the air diffusing across the alveolar-capillary membrane, vital for oxygen and carbon dioxide exchange.
- Gas exchange occurs across moist alveolar surfaces and happens down partial pressure gradients.
Peripheral and Neural Receptors
- Peripheral receptors include cough receptors, stretch receptors, and C-fibers.
- Neural receptors are in the medulla oblongata, and pons, that regulate breathing.
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