Respiratory System Overview

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Questions and Answers

What is the primary purpose of controlling breathing?

  • To increase the rate of carbon dioxide production
  • To ensure maximum carbon dioxide levels in the blood
  • To maximize oxygen saturation of haemoglobin and minimize work of breathing (correct)
  • To allow for reflex actions such as coughing

What occurs to CO2 levels and pH when the ventilation rate (V̇E) is halved?

  • CO2 levels decrease, causing pH to rise
  • CO2 levels increase, causing pH to fall (correct)
  • CO2 levels fluctuate but do not significantly affect pH
  • CO2 levels remain stable, with no effect on pH

Which neural respiratory centre is primarily responsible for automatic control of breathing?

  • Thalamus and hypothalamus
  • Cerebral cortex
  • Spinal cord
  • Medulla oblongata and pons (correct)

Which type of receptor is primarily responsible for the protective reflex against lung over-inflation?

<p>Stretch receptors (D)</p> Signup and view all the answers

Which response is NOT initiated by cough receptors found in the upper airways?

<p>Deep inhalation (C)</p> Signup and view all the answers

What is the main characteristic of COPD?

<p>Irreversible narrowing of the airways (B)</p> Signup and view all the answers

Which pressure is negative during normal resting inspiration?

<p>Pleural pressure (D)</p> Signup and view all the answers

What does lung compliance refer to?

<p>The ease of lung expansion per unit of pressure (D)</p> Signup and view all the answers

Asthma attacks are primarily associated with which mechanism?

<p>Airway obstruction from bronchoconstriction (A)</p> Signup and view all the answers

What is the primary risk factor for developing COPD?

<p>Smoking tobacco (B)</p> Signup and view all the answers

How does gas exchange occur in the lungs?

<p>By passive diffusion across pressure gradients (A)</p> Signup and view all the answers

What is the primary consequence of hypercapnia?

<p>Increased acidity in the body fluids (D)</p> Signup and view all the answers

What is the primary action that fulfills the main function of the lungs?

<p>Gas exchange and transport (A)</p> Signup and view all the answers

What patient demographic is most affected by asthma in the UK?

<p>Atopic individuals sensitive to allergens (D)</p> Signup and view all the answers

Which structure is NOT part of the upper respiratory tract?

<p>Bronchi (B)</p> Signup and view all the answers

How many lobes does the right lung have compared to the left lung?

<p>Three more lobes (A)</p> Signup and view all the answers

At what generation number does the respiratory zone begin?

<p>17 (B)</p> Signup and view all the answers

Which of the following correctly describes the conducting zone of the respiratory system?

<p>It conducts air without facilitating gas exchange (B)</p> Signup and view all the answers

What is the normal atmospheric pressure at sea level?

<p>101.325 kPa (C), 760 mmHg (D)</p> Signup and view all the answers

Which gas is primarily removed from the tissues by the lungs?

<p>Carbon Dioxide (CO2) (D)</p> Signup and view all the answers

What structure terminates the bronchial tree?

<p>Alveoli (D)</p> Signup and view all the answers

Flashcards

Control of Breathing

The process that governs how much we breathe, ensuring enough oxygen to maintain proper blood saturation while minimizing breathing effort. It also maintains a balanced level of carbon dioxide in the blood, crucial for blood's pH.

Neural Respiratory Centres

The brain regions responsible for the automatic control of breathing, located in the medulla oblongata and pons of the brainstem.

Peripheral Receptors

Specialized sensory cells found in the airways and lungs, triggering responses like coughing, bronchoconstriction, or mucus release. These receptors are activated by irritants or excessive stretching.

Cough Receptors

Found in the upper airways and trachea-bronchial tree, these rapidly adapting receptors respond to irritants like dust or smoke, leading to coughing, bronchoconstriction, and mucus production.

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Stretch Receptors

Slow adapting receptors located in the smooth muscle of airways. They detect excessive stretching and trigger reflex responses to protect the lungs from over-inflation.

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Partial Pressure (P)

The pressure exerted by a specific gas in a mixture of gases, like air. It's independent of the pressure of other gases present.

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Pleural Pressure (Ppl)

The pressure in the space between the two layers of pleura surrounding the lungs. It's usually negative during normal breathing.

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Alveolar Pressure (Palv)

The pressure inside the alveoli, the tiny air sacs in the lungs. It fluctuates with breathing.

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Lung Compliance (CL)

The ability of the lungs to expand for each unit of pressure change. A measure of lung elasticity.

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Chronic Obstructive Pulmonary Disease (COPD)

A group of respiratory diseases characterized by irreversible airway narrowing, making exhaling difficult. Includes conditions like chronic bronchitis and emphysema.

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Asthma

A respiratory condition marked by attacks of shortness of breath, coughing, and wheezing due to reversible airway narrowing.

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Gas Exchange

The movement of oxygen (O2) and carbon dioxide (CO2) across the thin membrane between alveoli and capillaries.

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Passive Diffusion

The process by which gases move from areas of high pressure to areas of low pressure. This is how O2 and CO2 move across the alveolar-capillary membrane.

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What is the main function of the lungs?

The primary function of the lungs is to provide oxygen (O2) to the body's tissues and remove carbon dioxide (CO2) as a waste product. This exchange of gases is crucial for cellular respiration, the process that generates energy for our cells.

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What is internal respiration?

Internal respiration refers to the process of gas exchange that occurs at the cellular level, within the mitochondria. This is where oxygen is used to produce ATP (adenosine triphosphate) for energy, while carbon dioxide is released as a by-product.

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What structures make up the upper respiratory tract?

The upper respiratory tract is the initial part of the respiratory system and includes the nasal cavity, pharynx, and larynx. These structures are responsible for filtering, warming, and humidifying incoming air, as well as producing sound.

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What structures make up the lower respiratory tract?

The lower respiratory tract is the portion of the respiratory system that extends from the trachea to the alveoli. It consists of the trachea, bronchi, bronchioles, and alveoli, and its primary function is gas exchange.

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How many lobes does each lung have?

The right lung has three lobes, while the left lung has only two lobes due to the space occupied by the heart. This arrangement allows for efficient gas exchange in both lungs.

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How are the bronchial branches organized?

Each branching sequence of the bronchial tree within the lungs is assigned a generation number. The trachea's split into two main bronchi marks generation number 1, and the final generation number is approximately 23.

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Where does the respiratory zone begin?

The respiratory zone begins after generation 17 in the bronchial tree, where the terminal respiratory units allow for gas diffusion across their membranes. This is where gas exchange occurs.

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What is the conducting zone?

The conducting zone encompasses the airways before generation 17, where the primary function is to move air to the respiratory zone without gas exchange. Think of this as the transport system.

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Study Notes

Respiratory System Overview

  • The respiratory system's main function is providing oxygen to tissues and removing carbon dioxide.
  • It includes the mechanics of breathing, gas exchange, and breathing control.
  • The process involves bringing oxygen into the lungs and removing carbon dioxide from the body.

Composition of Air

  • Nitrogen makes up the largest portion of the atmosphere (approximately 78.06%).
  • Oxygen constitutes about 20.98%.
  • Carbon dioxide is present in a small amount (approximately 0.04%).
  • Helium and argon make up the remaining percentage.

Organization of the Respiratory System

  • The respiratory system is divided into upper and lower respiratory tracts.
  • The upper respiratory tract includes the nasal cavity, pharynx, and larynx.
  • The lower respiratory tract involves the trachea, bronchi, and bronchial tree which terminates in the alveoli.

Lung Lobes

  • The right lung has three lobes.
  • The left lung has two lobes.
  • The space taken by the pericardium for the heart accounts for the difference.

Lung Structure - Generation Numbers

  • The branching sequence of the bronchial tree has a generation number.
  • The generation number 1 represents where the trachea splits into two main bronchi.
  • The final generation number is approximately 23.

Lung Volumes and Capacities

  • Lung volumes indicate the amount of air moved in and out of the lungs.
  • Lung capacities encompass various combinations of lung volumes and are used to determine a person's lung function.
  • Common lung volumes include tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume.
  • Common lung capacities include total lung capacity, vital capacity, inspiratory capacity, and functional residual capacity.
  • These are measured using a spirometer.

Mechanics of Pulmonary Ventilation

  • Atmospheric pressure at sea level is normally 101.325 kPa (760 mmHg) or 1 atm.
  • The pressure exerted by a gas is the partial pressure.
  • Pleural pressure is the pressure in the pleural space between visceral and parietal pleurae.
  • Alveolar pressure is the pressure within the alveoli.
  • The extent of lung expansion per unit of pressure is lung compliance.

Control of Breathing

  • Control of breathing ensures sufficient oxygen saturation of hemoglobin and efficient work of breathing, with minimal effort.
  • Adjustments in breathing control mechanisms regulate carbon dioxide levels.
  • Breathing control can be modified to accommodate situations like blowing, holding breath, or speaking activities..
  • Peripheral receptors (located in the airways and lungs) are part of the feedback mechanism.
  • Neural centers in the brainstem (medulla oblongata, and pons) are responsible for maintaining automatic breathing.

Respiratory Diseases

  • Respiratory diseases are classified into obstructive and restrictive diseases.
  • Obstructive disorders, such as COPD, involve constriction of airways and resistance to airflow.
  • Restrictive diseases result in decreased functional volume of the lungs.
  • Examples of respiratory diseases are COPD, asthma.

Gas Exchange and Transport

  • Breathing involves air entering and the air diffusing across the alveolar-capillary membrane, vital for oxygen and carbon dioxide exchange.
  • Gas exchange occurs across moist alveolar surfaces and happens down partial pressure gradients.

Peripheral and Neural Receptors

  • Peripheral receptors include cough receptors, stretch receptors, and C-fibers.
  • Neural receptors are in the medulla oblongata, and pons, that regulate breathing.

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