Respiratory System - Lung Physiology
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Questions and Answers

What effect does maximum inspiration have on the anteroposterior thickness of the chest?

  • It increases by 20 percent. (correct)
  • It decreases by 20 percent.
  • It increases by 50 percent.
  • It remains the same.

Which muscles are primarily responsible for elevating the rib cage during inspiration?

  • Internal intercostals
  • External intercostals (correct)
  • Pectoral muscles
  • Abdominal recti

What role do the abdominal recti play during expiration?

  • They compress the abdominal contents upward against the diaphragm. (correct)
  • They lift the rib cage upward.
  • They pull the rib cage downward. (correct)
  • They do not contribute significantly.

What maintains the slight negative pressure in the pleural space during respiration?

<p>Continuous suction of excess fluid into lymphatic channels. (D)</p> Signup and view all the answers

What is the normal pleural pressure at the beginning of inspiration?

<p>–5 centimeters of water (C)</p> Signup and view all the answers

Which muscles assist in the elevation of the sternum during inspiration?

<p>Sternocleidomastoid muscles (C)</p> Signup and view all the answers

Which type of pressure is present in the thin space between the lung pleura and the chest wall pleura?

<p>Pleural pressure (C)</p> Signup and view all the answers

What happens to the lungs when there is no force to keep them inflated?

<p>They collapse like a balloon. (A)</p> Signup and view all the answers

What is the primary function of pulmonary ventilation?

<p>To facilitate the inflow and outflow of air between the atmosphere and the lung alveoli (C)</p> Signup and view all the answers

Which muscles primarily accomplish normal quiet breathing?

<p>Diaphragm (A)</p> Signup and view all the answers

What happens to the diaphragm during expiration?

<p>It relaxes (A)</p> Signup and view all the answers

What additional force assists with rapid expiration during heavy breathing?

<p>Contraction of the abdominal muscles (C)</p> Signup and view all the answers

Which method contributes to lung expansion by changing the chest cavity's shape?

<p>Elevating and depressing the ribs (C)</p> Signup and view all the answers

What term defines the ability of the lungs to expand and contract efficiently?

<p>Pulmonary compliance (C)</p> Signup and view all the answers

During normal inspiration, which muscle primarily contributes to expanding the thoracic cavity?

<p>Diaphragm (B)</p> Signup and view all the answers

What occurs to the rib cage during inhalation?

<p>It elevates and expands (D)</p> Signup and view all the answers

What primarily determines the elastic forces of the lung tissue?

<p>Elastin and collagen fibers interwoven among lung parenchyma (D)</p> Signup and view all the answers

Which of the following best explains the role of surfactant in the lungs?

<p>Surfactant reduces surface tension within the alveoli (D)</p> Signup and view all the answers

What is the effect of surfactant on the surface tension of water in the alveoli?

<p>Normal alveolar fluids without surfactant have lower surface tension than pure water (D)</p> Signup and view all the answers

Which statement accurately describes the difference between air-filled lungs and saline solution-filled lungs?

<p>Transpleural pressures required for air-filled lungs are significantly higher (B)</p> Signup and view all the answers

What percentage of the surface area of alveoli is comprised of type II alveolar epithelial cells?

<p>10 percent (A)</p> Signup and view all the answers

Which of the following accurately reflects the contribution of tissue elastic forces to total lung elasticity?

<p>They represent one-third of the total lung elasticity (D)</p> Signup and view all the answers

In terms of surface tension, what is the range for normal fluids in the alveoli with surfactant?

<p>5 to 30 dynes/cm (C)</p> Signup and view all the answers

What isolating condition occurs in saline solution-filled lungs compared to air-filled lungs?

<p>Absence of surface tension effects due to lack of air (D)</p> Signup and view all the answers

What is the average alveolar pressure during normal inspiration?

<p>-7.5 centimeters of water (D)</p> Signup and view all the answers

What must occur for air to flow into the alveoli during inspiration?

<p>Alveolar pressure must fall slightly below atmospheric pressure (C)</p> Signup and view all the answers

What is transpulmonary pressure a measure of?

<p>The pressure difference between alveoli and pleural pressure (D)</p> Signup and view all the answers

What is lung compliance defined as?

<p>The extent to which the lungs expand for each unit increase in transpulmonary pressure (D)</p> Signup and view all the answers

What is the average total compliance of both lungs in a normal adult?

<p>200 milliliters of air per centimeter of water (B)</p> Signup and view all the answers

During expiration, what is the alveolar pressure typically around?

<p>+1 centimeter of water (B)</p> Signup and view all the answers

What does the compliance diagram of the lungs represent?

<p>The elastic properties of the lung tissue for varying transpulmonary pressures (A)</p> Signup and view all the answers

What is the primary function of the negative pressure created in the thoracic cavity during inspiration?

<p>To allow air to flow into the alveoli (A)</p> Signup and view all the answers

What happens to the pressure in the alveoli when air passages are blocked?

<p>It attempts to collapse the alveoli. (C)</p> Signup and view all the answers

What is the calculated pressure in an average-sized alveolus lined with surfactant?

<p>4 centimeters of water pressure. (A)</p> Signup and view all the answers

How does the radius of the alveolus affect the pressure caused by surface tension?

<p>Pressure decreases as the radius increases. (A)</p> Signup and view all the answers

What is the pressure in an alveolus with a radius of 50 micrometers compared to one with a radius of 100 micrometers?

<p>It is double the pressure. (B)</p> Signup and view all the answers

When does surfactant typically begin to be secreted into the alveoli during gestation?

<p>Between the sixth and seventh months. (D)</p> Signup and view all the answers

What condition can occur in premature infants due to a lack of surfactant?

<p>Respiratory distress syndrome. (D)</p> Signup and view all the answers

What is the potential pressure difference in alveoli with little or no surfactant compared to those with normal surfactant levels?

<p>They can exert up to six to eight times greater pressure. (B)</p> Signup and view all the answers

What treatment is particularly important for managing respiratory distress syndrome in newborns?

<p>Properly applied continuous positive pressure breathing. (D)</p> Signup and view all the answers

Flashcards

Pulmonary Ventilation

The movement of air between the atmosphere and the lungs.

Diaphragm Contraction

The downward movement of the diaphragm, which increases the vertical dimension of the chest cavity, leading to lung expansion.

Rib Cage Elevation

The upward movement of the rib cage, increasing the anteroposterior diameter of the chest cavity, leading to lung expansion.

Elastic Recoil of Lungs

The force that causes air to be expelled during normal expiration.

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Abdominal Muscles

Muscles that assist in forced expiration by pushing abdominal contents upwards, increasing pressure on the diaphragm.

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Diffusion of Gases

The process by which oxygen moves from the alveoli into the bloodstream and carbon dioxide moves from the bloodstream into the alveoli.

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Lung Compliance

The ability of the lungs to expand.

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Intra-alveolar Pressure

The pressure inside the alveoli of the lungs.

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Alveolar Pressure

The pressure inside the alveoli of the lungs, which changes during breathing to facilitate air flow.

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Transpulmonary Pressure

The pressure difference between the alveoli and the pleural space surrounding the lungs.

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Inspiration

The inward flow of air into the lungs, caused by a decrease in alveolar pressure relative to atmospheric pressure.

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Expiration

The outward flow of air from the lungs, caused by an increase in alveolar pressure relative to atmospheric pressure.

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Recoil Pressure

The force that tends to collapse the lungs due to their elasticity. It's opposed by the transpulmonary pressure.

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Compliance Diagram of the Lungs

A graphical representation of lung compliance, displaying how lung volume changes with different transpulmonary pressure values.

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Pressure Changes During Breathing

During quiet inspiration, the pressure inside the alveoli drops to a value slightly below atmospheric pressure, drawing in air. During expiration, the pressure increases, forcing air out.

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What is pleural pressure?

The pressure in the fluid-filled space between the lung pleura and the chest wall pleura, normally slightly negative.

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What maintains lung inflation?

The force that keeps the lungs inflated and prevents them from collapsing, caused by a slightly negative pleural pressure.

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Which muscles are the primary inspiratory muscles?

The primary muscles responsible for elevating the rib cage, crucial for increasing the chest cavity volume during inspiration. These muscles lie between the ribs.

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What are some accessory inspiratory muscles?

The muscles that help elevate the rib cage during inspiration, including the sternocleidomastoid, anterior serrati, and scalene muscles.

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How does the chest cavity expand during inspiration?

A condition in which the chest wall expands during inspiration due to the contraction of inspiratory muscles, leading to increased lung volume.

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Define pulmonary ventilation.

The movement of air in and out of the lungs, driven by pressure differences between the lungs and the atmosphere.

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Which muscles aid in expiration?

The muscles that depress the rib cage, assisting in expiration, primarily the abdominal recti and internal intercostals.

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What causes the movement of air out of the lungs?

The force that causes air to be expelled from the lungs during expiration, driven by the elastic recoil of the lungs and the relaxation of inspiratory muscles.

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Elastic forces of lung tissue

Elastic forces in the lungs are caused by the stretchy nature of the lung tissue itself, consisting of elastin and collagen fibers.

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Surface tension in the lungs

Surface tension is caused by the attraction between water molecules lining the alveoli. This force tries to minimize the surface area, leading to a collapsing force.

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Surfactant's role

Surfactant, a special substance secreted by type II alveolar cells, reduces surface tension in the alveoli, making it easier for the lungs to expand and preventing collapse.

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Compliance diagram

The compliance diagram graphically illustrates the relationship between lung volume and transpulmonary pressure. It shows how lung volume changes with different pressure values.

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Elastic forces contribution

The air-fluid interface in the alveoli contributes to about two-thirds of the total lung elasticity, while the elastic forces of the lung tissue itself contribute to only about one-third.

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Pressure in Occluded Alveoli

Surface tension in the alveoli tends to collapse them when air passages are blocked, creating positive pressure and pushing air out. This pressure is inversely proportional to the alveoli's radius, meaning smaller alveoli have higher pressure.

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What is surfactant?

A substance that reduces surface tension in the alveoli, preventing their collapse and decreasing the effort needed for breathing. It's crucial for lung function, especially in premature babies.

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What is respiratory distress syndrome of the newborn?

The condition where the alveoli have a strong tendency to collapse due to insufficient surfactant, especially in premature babies, leading to breathing difficulties. This can be fatal without proper treatment.

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Formula for Pressure in Alveoli

The formula relates pressure in the alveoli to surface tension and radius: Pressure = 2 x Surface Tension / Radius. Smaller radius means higher pressure.

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Alveolar Radius and Pressure

The radius of the alveolus plays a significant role in the pressure generated by surface tension. Smaller alveoli experience greater pressure due to the smaller surface area for the same amount of surface tension.

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Surfactant Development

Surfactant production begins around the sixth or seventh month of gestation, making premature babies more susceptible to respiratory distress syndrome due to their limited surfactant levels.

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Study Notes

Respiratory System - Lung Physiology

  • The goals of respiration are to provide oxygen to tissues and remove carbon dioxide.
  • Pulmonary ventilation is the inflow and outflow of air between the atmosphere and lung alveoli.
  • Oxygen and carbon dioxide diffuse between alveoli and blood.
  • Oxygen and carbon dioxide are transported in blood to and from body tissues.
  • Respiration is regulated.

Mechanics of Pulmonary Ventilation

  • Lung expansion and contraction occur through:
    • Downward and upward movement of the diaphragm, changing the chest cavity.
    • Elevation and depression of the ribs, altering the chest cavity’s anteroposterior diameter.
  • Normal breathing is primarily driven by diaphragm movement.
  • Inspiration: Diaphragm contracts, pulling lungs downward. Lungs expand, air flows in.
  • Expiration: Diaphragm relaxes, elastic recoil compresses lungs and expels air.
  • Additional force during heavy breathing comes from abdominal muscles.

Muscles of Respiration

  • External intercostals are the primary muscles that raise the rib cage.
  • Sternocleidomastoid, anterior serrati, and scalene muscles assist in rib cage elevation.
  • Internal intercostals and abdominal muscles aid in rib cage depression.

Pressures and Lung Movement

  • Pleural pressure is the pressure in the thin space between lung and chest wall.
  • Normal pleural pressure is slightly negative (-5 cm H₂O) to keep lungs inflated.
  • Expansion of the chest stretches the lungs and further reduces pleural pressure to about (-7.5 cm H₂O).
  • Alveolar pressure: Pressure inside the alveoli.
  • Inspiration: Alveolar pressure becomes slightly negative (below atmospheric pressure) to draw air into lungs.
  • Expiration: Alveolar pressure increases (above atmospheric pressure) to force air out of lungs.

Lung Compliance

  • Lung compliance is the extent to which lungs expand for a given change in transpulmonary pressure.
  • Normal lung compliance is approximately 200 mL air per cm H₂O of transpulmonary pressure.
  • Compliance is determined by: 
    • Lung tissue elasticity.
    • Surface tension of fluid lining the alveoli.

Surfactant

  • Surfactant is a substance produced by type II alveolar cells.
  • It reduces surface tension in the alveoli.
  • Reduced surface tension prevents alveolar collapse during exhalation.
  • Important for premature babies, as they often have underdeveloped surfactant production.

Alveolar Interdependence

  • Alveoli are interconnected.
  • When one alveolus collapses, neighboring alveoli help keep it open by increasing their size.
  • This is crucial in preventing complete lung collapse.

Reduced Lung Compliance Causes

  • Pulmonary fibrosis
  • Alveolar edema
  • Atelectasis
  • Hemo/pneumothorax

Increased Lung Compliance Causes

  • Emphysema
  • Normal aging
  • Pulmonary emphysema

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Description

Test your knowledge on the respiratory system and lung physiology. Explore concepts such as pulmonary ventilation, gas exchange, and the mechanics of breathing. This quiz covers the essentials of how our lungs function and the muscles involved in respiration.

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