Respiratory System and Disease
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Questions and Answers

Which part of the upper respiratory tract is responsible for the passage of air and food?

  • Oropharynx (correct)
  • Nasopharynx
  • Laryngopharynx
  • Nasal cavity
  • What is the primary function of the commensal microbiota in host innate defense mechanisms?

  • Trapping microbes
  • Niche occupation, preventing bad bacteria from occupying the space (correct)
  • Enhancing mucin secretion
  • Removing microbes
  • Which of the following is NOT a host innate defense mechanism against respiratory microbes?

  • Mucus flow
  • Epithelial cell tight junctions
  • Air flow
  • Vector transmission (correct)
  • What is the function of Lysozyme in host innate responses?

    <p>Bacterial cell wall destruction (D)</p> Signup and view all the answers

    Which age group is more prone to respiratory disease due to their role as reservoirs?

    <p>None of the above (D)</p> Signup and view all the answers

    What is the general role of effector molecules in host innate response?

    <p>To destroy and remove pathogens (A)</p> Signup and view all the answers

    Where are the pathogen recognition receptors located on epithelial cells?

    <p>Internally (A)</p> Signup and view all the answers

    What is the function of GM-CSF cytokine produced by epithelial cells?

    <p>Growth factor, activates neutrophils (B)</p> Signup and view all the answers

    Which of the following is a common symptom of rhinoviruses?

    <p>Hypersecretion of mucus (A)</p> Signup and view all the answers

    What is the name of the receptor that RV-A binds to on epithelial cells?

    <p>ICAM-1 (D)</p> Signup and view all the answers

    What is the age group in which RSV is more common than flu?

    <p>Less than 12 months (A)</p> Signup and view all the answers

    What is the treatment used for RSV?

    <p>Neutralising antibody to block infection (B)</p> Signup and view all the answers

    What is the family of viruses that the influenza virus comes from?

    <p>Orthomyxoviridae (D)</p> Signup and view all the answers

    What is the result of epithelial cell infection?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the property of the family of virus that rhinoviruses come from?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the result of RSV infection in infants?

    <p>RSV bronchiolitis (A)</p> Signup and view all the answers

    What is the role of neuraminidase in influenza?

    <p>Liquifies mucus to assist with aerosol production and transmission (C)</p> Signup and view all the answers

    What is the primary cause of symptoms in influenza?

    <p>Immune response to the virus (D)</p> Signup and view all the answers

    What is the term for the process by which influenza viruses undergo minor genetic changes, leading to epidemics?

    <p>Antigenic drift (C)</p> Signup and view all the answers

    What is an example of a zoonotic disease?

    <p>SARS-CoV-2 (B)</p> Signup and view all the answers

    What type of infection is whooping cough?

    <p>Bacterial (C)</p> Signup and view all the answers

    What is the receptor that SARS-CoV-2 binds to?

    <p>ACE2 receptor (A)</p> Signup and view all the answers

    What is the primary difference between SARS-CoV and SARS-CoV-2?

    <p>SARS-CoV-2 is more contagious (D)</p> Signup and view all the answers

    What is the most effective way that SARS-CoV-2 is transmitted?

    <p>Airborne (A)</p> Signup and view all the answers

    What is the term for the process by which influenza viruses undergo major genetic changes, leading to pandemics?

    <p>Antigenic shift (D)</p> Signup and view all the answers

    What is the bacterium that causes whooping cough?

    <p>Bordetella pertussis (D)</p> Signup and view all the answers

    What are the main symptoms of COVID-19?

    <p>Fever, cough, shortness of breath, and loss of smell (B)</p> Signup and view all the answers

    What is the primary function of Bordetella pertussis toxins?

    <p>To trigger coughing (C)</p> Signup and view all the answers

    What type of vaccine is used to prevent whooping cough?

    <p>Acellular (A)</p> Signup and view all the answers

    What is the difference between latent TB and active TB?

    <p>Latent TB is asymptomatic, active TB has symptoms (D)</p> Signup and view all the answers

    What are the three risk factors for TB?

    <p>HIV, contact with active TB case, and corticosteroid therapy (D)</p> Signup and view all the answers

    What is the purpose of granulomas in TB?

    <p>To wall off infective cells (D)</p> Signup and view all the answers

    What is primary tuberculosis?

    <p>An initial mycobacterial infection in patients never previously exposed to TB (C)</p> Signup and view all the answers

    What is the purpose of the tuberculin test?

    <p>To show immunity to TB (B)</p> Signup and view all the answers

    What is the treatment for post-primary TB?

    <p>Two antibiotics for 6 months, and two additional antibiotics for the first 2 months (B)</p> Signup and view all the answers

    What is a complication of post-primary TB?

    <p>Miliary TB (C)</p> Signup and view all the answers

    What is the purpose of contact tracing in TB prevention?

    <p>To screen for TB contacts (D)</p> Signup and view all the answers

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