Podcast Beta
Questions and Answers
What is the primary purpose of using a flexible fibreoptic bronchoscope?
Which of the following is NOT a type of specimen that can be collected during bronchoscopy?
What is the term for biopsies taken by passing forceps through the bronchial wall?
What is the gold standard investigation for Sarcoidosis and Diffuse Malignancy?
Signup and view all the answers
What is the term for the extent of shadowing seen on an X-ray?
Signup and view all the answers
What is the purpose of combining Computed Tomography (CT) and Positron Emission Tomography (PET) scans?
Signup and view all the answers
What type of anaesthesia is usually used for bronchoscopy?
Signup and view all the answers
What is the term for the normal position of the diaphragm as shown in the figure?
Signup and view all the answers
Which diagnostic test is used to identify a reaction to fungi such as Aspergillus?
Signup and view all the answers
What is the primary indication for performing a rigid bronchoscopy?
Signup and view all the answers
Which of the following is a marker of fungal infection?
Signup and view all the answers
What is the primary use of endobronchial ultrasound (EBUS)?
Signup and view all the answers
Which test is used to diagnose invasive aspergillosis?
Signup and view all the answers
What is the primary use of interferon-gamma release assays?
Signup and view all the answers
What is the primary indication for performing a bronchoscopy?
Signup and view all the answers
Which of the following can be used to diagnose mediastinal lymphadenopathy caused by tuberculosis or sarcoidosis?
Signup and view all the answers
What is the primary utility of thoracoscopy in the evaluation of pleural disease?
Signup and view all the answers
Which of the following is NOT a potential application of endoscopic ultrasound?
Signup and view all the answers
What is the primary advantage of obtaining a larger tissue biopsy in lung cancer diagnosis?
Signup and view all the answers
Which of the following conditions may be distinguished from others based on differential cell counts in bronchial lavage fluid?
Signup and view all the answers
What is the primary route of biopsy for lymph nodes in the lower mediastinum?
Signup and view all the answers
What is the primary utility of cytological examination of exfoliated cells?
Signup and view all the answers
Which of the following is a potential application of mediastinoscopy?
Signup and view all the answers
What is the primary advantage of using histopathology over cytological examination?
Signup and view all the answers
Study Notes
Bronchoscopy
- The trachea and the first 3-4 generations of bronchi can be inspected using a flexible fiberoptic bronchoscope.
- Bronchoscopy can be performed under local anesthesia with sedation on an outpatient basis.
- Abnormal tissue can be biopsied, and bronchial brushings, washings, or aspirates can be taken for cytological or bacteriological examination.
Biopsy and Tissue Sampling
- Small biopsy specimens of lung tissue can be taken by forceps passed through the bronchial wall (transbronchial biopsies).
- Lymph nodes in the lower mediastinum can be biopsied via the esophagus using an endoscopic ultrasound.
- Thoracoscopy facilitates biopsy under direct vision and is the gold standard for the evaluation of the pleural surfaces.
Imaging Investigations
- Computed tomography (CT) and positron emission tomography (PET) can be combined to reveal intrathoracic metastases.
- CT scans can be used to diagnose bronchocentric disorders such as sarcoidosis.
Cytology and Histopathology
- Cytological examination of exfoliated cells in pleural fluid or bronchial brushings and washings can support a diagnosis of malignancy.
- Histopathology allows immunohistochemistry and genetic testing to characterize the tumor and guide variant-specific therapy.
- Histopathology can also identify microorganisms using conventional staining or NAATs.
Serological Investigations
- IgG enzyme immunoassay or identification of serum precipitins (antibodies) can be used to identify a reaction to fungi such as Aspergillus.
- The presence of pneumococcal antigen in sputum, blood, or urine may be of diagnostic importance in pneumonia.
- Respiratory viruses can be detected in nose/throat swabs by immunofluorescence.
- Legionella infection may be diagnosed by detection of a Legionella antigen in urine.
- β-1,3-D-glucan detection (in blood) is a marker of fungal infection.
- Aspergillus galactomannan (in blood and bronchial lavage fluid) is used to diagnose invasive aspergillosis.
- Interferon-gamma release assays are useful in the detection of latent tuberculosis.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
This quiz covers the anatomy of the respiratory system, including the diaphragm, trachea, and bronchi. Test your knowledge of the structures and their relationships.
