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Questions and Answers
What is the typical ventilatory pattern seen in lung fibrosis?
What is the typical ventilatory pattern seen in lung fibrosis?
- Mixed pattern with reduced FEV1%, but normal TLC
- Obstructive pattern with normal TLC, FEV1, and FVC
- Restrictive pattern with reduced TLC, FEV1, and FVC (correct)
- Normal pattern with increased FEV1%, but reduced FVC
Why does hypoxemia occur in advanced IPF according to the text?
Why does hypoxemia occur in advanced IPF according to the text?
- Related to normal capillary transit time in fibrotic areas
- Due to even airflow distribution in the lungs
- Resulting from stable regional compliance in fibrosis
- Caused by significant mismatching in regional ventilation (correct)
How is diffusion impairment related to resting hypoxemia in lung fibrosis?
How is diffusion impairment related to resting hypoxemia in lung fibrosis?
- Diffusion impairment contributes significantly to resting hypoxemia
- Diffusion impairment does not affect resting hypoxemia (correct)
- Diffusion impairment only affects exercise-induced desaturation
- Diffusion impairment completely resolves resting hypoxemia
What is the usual arterial PCO2 in lung fibrosis patients according to the text?
What is the usual arterial PCO2 in lung fibrosis patients according to the text?
Why does cardiac output tend to be low in advanced IPF according to the text?
Why does cardiac output tend to be low in advanced IPF according to the text?
How does diffusion impairment contribute to exercise-induced desaturation in lung fibrosis?
How does diffusion impairment contribute to exercise-induced desaturation in lung fibrosis?
What is the normal ratio of FEV1/FVC?
What is the normal ratio of FEV1/FVC?
In a person with obstructive lung disease, which of the following is likely to be reduced?
In a person with obstructive lung disease, which of the following is likely to be reduced?
In pulmonary arterial hypertension, what is the characteristic change in the pulmonary arteries?
In pulmonary arterial hypertension, what is the characteristic change in the pulmonary arteries?
What is the term for the amount of air that remains in the lungs after normal expiration?
What is the term for the amount of air that remains in the lungs after normal expiration?
In a person with restrictive lung disease, which of the following is likely to be reduced?
In a person with restrictive lung disease, which of the following is likely to be reduced?
What is the term for the amount of air that can be exhaled rapidly and forcefully after a full inspiration?
What is the term for the amount of air that can be exhaled rapidly and forcefully after a full inspiration?
What is the primary implication of hypercapnia?
What is the primary implication of hypercapnia?
In a normal lung, how long does it take for hemoglobin to become completely saturated with oxygen?
In a normal lung, how long does it take for hemoglobin to become completely saturated with oxygen?
What happens to the mixed venous PO2 in the setting of exercise?
What happens to the mixed venous PO2 in the setting of exercise?
What is the effect of lung fibrosis on the alveolar–capillary barrier?
What is the effect of lung fibrosis on the alveolar–capillary barrier?
What is the typical transit time for an erythrocyte through an alveolar capillary?
What is the typical transit time for an erythrocyte through an alveolar capillary?
What happens to alveolar end-capillary blood in the setting of lung fibrosis and shortened capillary transit time?
What happens to alveolar end-capillary blood in the setting of lung fibrosis and shortened capillary transit time?