Respiratory Medications Overview
25 Questions
3 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary action of anti-IL-4/IL-13 medications like Dupilumab?

  • Increase mucus production
  • Block interleukins involved in inflammation (correct)
  • Reduce airway irritation
  • Suppress the central cough reflex
  • Which of the following is a central-acting antitussive?

  • Menthol
  • Codeine
  • Dextromethorphan (correct)
  • Guaifenesin
  • What is the mechanism of action of expectorants such as Guaifenesin?

  • Increasing the production of thinner mucus (correct)
  • Blocking nerve signals for cough
  • Thickening mucus production
  • Directly suppressing the cough reflex
  • Which type of antitussive is typically less commonly used in modern clinical practice?

    <p>Menthol (A)</p> Signup and view all the answers

    Which medication is primarily used as an expectorant?

    <p>Guaifenesin (A)</p> Signup and view all the answers

    What is the primary mechanism of action for antihistamines?

    <p>Blocking histamine receptors (A)</p> Signup and view all the answers

    Which type of antihistamine is more likely to cause sedation?

    <p>First-generation antihistamines (A)</p> Signup and view all the answers

    What is a common systemic side effect of oral decongestants?

    <p>Increased heart rate (A)</p> Signup and view all the answers

    What mechanism do decongestants use to relieve nasal congestion?

    <p>Vasoconstriction of blood vessels (B)</p> Signup and view all the answers

    What can occur if topical decongestants are used for more than a few days?

    <p>Rebound congestion (C)</p> Signup and view all the answers

    Which of the following is NOT a common example of an antihistamine?

    <p>Dextromethorphan (B)</p> Signup and view all the answers

    What is the primary use of antitussives?

    <p>Suppressing the cough reflex (B)</p> Signup and view all the answers

    What is the primary mechanism by which expectorants help the respiratory tract?

    <p>Increasing mucus production and reducing viscosity (D)</p> Signup and view all the answers

    Which drug class is often used for more severe coughing and carries risks of dependency?

    <p>Antitussives (B)</p> Signup and view all the answers

    What type of medication is Guaifenesin commonly used as?

    <p>Expectorant (D)</p> Signup and view all the answers

    What mechanism do beta-2 adrenergic agonists utilize to aid in breathing?

    <p>Stimulating beta-2 adrenergic receptors (A)</p> Signup and view all the answers

    Why are inhaled corticosteroids preferred for long-term management of respiratory conditions?

    <p>They have fewer side effects than systemic steroids (A)</p> Signup and view all the answers

    Mast cell stabilizers act by preventing the release of which inflammatory mediator?

    <p>Histamine (A)</p> Signup and view all the answers

    Which medication is an example of a long-acting muscarinic antagonist (LAMA)?

    <p>Tiotropium (C)</p> Signup and view all the answers

    Leukotriene receptor antagonists primarily prevent which of the following?

    <p>Inflammation and bronchoconstriction (C)</p> Signup and view all the answers

    What role do PDE4 inhibitors play in respiratory treatment?

    <p>They reduce inflammation by increasing cAMP levels (C)</p> Signup and view all the answers

    Which of the following is a primary side effect associated with systemic corticosteroids?

    <p>Weight gain (C)</p> Signup and view all the answers

    Which of the following best describes the mechanism of action of anticholinergics in treating respiratory conditions?

    <p>They block muscarinic receptors to prevent bronchoconstriction (D)</p> Signup and view all the answers

    An example of a monoclonal antibody used for severe asthma treatment targets which immune system mediator?

    <p>IgE (B)</p> Signup and view all the answers

    What is the main indication for using 5-lipoxygenase inhibitors in respiratory therapy?

    <p>To reduce bronchoconstriction by preventing leukotriene formation (A)</p> Signup and view all the answers

    Flashcards

    Expectorants

    Medications that help clear mucus from the airways by making it thinner and easier to expel.

    Antihistamines

    Medications that block histamine receptors, reducing allergic reactions like sneezing, itching, and congestion.

    H1 Receptors

    Receptors in tissues like the skin and respiratory tract where histamine binds, causing allergy symptoms.

    First-generation Antihistamines

    Antihistamines like diphenhydramine that can cause drowsiness due to crossing the blood-brain barrier.

    Signup and view all the flashcards

    Second-generation Antihistamines

    Antihistamines like loratadine and cetirizine that are less likely to cause drowsiness.

    Signup and view all the flashcards

    Decongestants

    Medications that shrink swollen nasal tissues by stimulating alpha-adrenergic receptors, improving airflow.

    Signup and view all the flashcards

    Oral Decongestants

    Decongestants taken by mouth, such as pseudoephedrine, that can affect heart rate and blood pressure.

    Signup and view all the flashcards

    Topical Decongestants

    Decongestants applied directly to the nose, like oxymetazoline, that can cause rebound congestion if used for too long.

    Signup and view all the flashcards

    Antitussives (Cough Suppressants)

    Medications that reduce the cough reflex, often used for dry coughs.

    Signup and view all the flashcards

    Dextromethorphan

    A non-opioid antitussive, often found in over-the-counter cough medications.

    Signup and view all the flashcards

    Codeine

    An opioid antitussive used for more severe coughing, but it carries potential side effects and addiction risks.

    Signup and view all the flashcards

    Guaifenesin

    A common expectorant often found in combination cold medications.

    Signup and view all the flashcards

    Bronchodilator

    Drug that relaxes airway muscles, widening the airways for easier breathing.

    Signup and view all the flashcards

    Beta-2 Adrenergic Agonist

    Stimulates receptors in airway muscles, relaxing them and widening the airways.

    Signup and view all the flashcards

    Short-Acting Beta-Agonist (SABA)

    Fast-acting bronchodilator used for immediate relief, like during an asthma attack.

    Signup and view all the flashcards

    Long-Acting Beta-Agonist (LABA)

    Provides longer-lasting bronchodilation, used for prevention and control of airway narrowing.

    Signup and view all the flashcards

    Anticholinergic (Muscarinic Antagonist)

    Blocks receptors in the airways, preventing muscle tightening and airway narrowing.

    Signup and view all the flashcards

    Inhaled Corticosteroid (ICS)

    Reduces inflammation directly in the airways, typically used for long-term asthma or COPD management.

    Signup and view all the flashcards

    Leukotriene Modifier

    Prevents bronchoconstriction and inflammation by blocking leukotrienes, inflammatory chemicals.

    Signup and view all the flashcards

    Leukotriene Receptor Antagonist (LTRA)

    Blocks leukotriene receptors, preventing those chemicals from causing inflammation.

    Signup and view all the flashcards

    5-Lipoxygenase Inhibitor

    Prevents the production of leukotrienes by blocking the enzyme that makes them.

    Signup and view all the flashcards

    Mast Cell Stabilizer

    Prevents histamine and other inflammatory mediators from being released by mast cells.

    Signup and view all the flashcards

    Monoclonal Antibody

    Biologic that targets specific immune components involved in inflammation, such as IgE or IL-5.

    Signup and view all the flashcards

    Study Notes

    Respiratory Medications

    • Used to treat various respiratory conditions, including colds, allergies, asthma, and COPD.

    Antihistamines

    • Mechanism: Block histamine H1 receptors, reducing allergic reactions. Histamine is a chemical released during allergic responses.
    • Effect: Reduce symptoms like sneezing, itching, congestion, runny nose.
    • Types:
      • First-generation (e.g., diphenhydramine): Often cause sedation.
      • Second-generation (e.g., loratadine, cetirizine): Less likely to cause sedation.
    • Examples: Diphenhydramine (Benadryl), loratadine (Claritin), cetirizine (Zyrtec).

    Decongestants

    • Mechanism: Stimulate alpha-adrenergic receptors (α1) in nasal blood vessels, causing vasoconstriction to reduce swelling.
    • Effect: Relieve nasal congestion and improve airflow.
    • Types:
      • Oral (e.g., pseudoephedrine): Can cause systemic side effects.
      • Topical (e.g., nasal sprays): May cause rebound congestion with prolonged use.
    • Examples: Pseudoephedrine (Sudafed), phenylephrine, oxymetazoline (Afrin).

    Antitussives (Cough Suppressants)

    • Mechanism: Suppress the cough reflex.
    • Types:
      • Central-acting: Inhibit cough center in the brain.
      • Peripheral-acting: Reduce airway irritation.
    • Examples:
      • Dextromethorphan: Common, non-opioid.
      • Codeine: Opioid, used for more severe cases (with caution due to side effects and dependency risk).

    Expectorants

    • Mechanism: Increase mucus production and reduce mucus viscosity, facilitating clearing of mucus from the airways.
    • Effect: Thins and loosens mucus, makes it easier to cough up.
    • Example: Guaifenesin (Mucinex).
    • Important Note: Staying hydrated enhances effectiveness.

    Bronchodilators

    • Relax airway muscles, making breathing easier.
    • Used for asthma and COPD.

    Beta-2 Adrenergic Agonists

    • Mechanism: Stimulate beta-2 adrenergic receptors in the lungs, causing bronchodilation.
    • Types:
      • Short-acting (SABA): Fast-acting, used in emergencies.
      • Long-acting (LABA): For long-term control.
    • Examples: Albuterol (Salbutamol), Levalbuterol, Salmeterol, Formoterol.

    Anticholinergics (Muscarinic Antagonists)

    • Mechanism: Block muscarinic receptors, preventing bronchoconstriction.
    • Types:
      • Short-acting (SAMA): For immediate relief.
      • Long-acting (LAMA): For long-term control.
    • Examples: Ipratropium, Tiotropium, Aclidinium.

    Corticosteroids

    • Reduce airway inflammation in chronic conditions like asthma and COPD.
    • Types:
      • Inhaled: For long-term management.
      • Oral/Systemic: For short-term flare-ups or severe cases.
    • Examples: Fluticasone, Budesonide, Beclometasone (inhaled), Prednisone, Methylprednisolone (oral/systemic).

    Leukotriene Modifiers

    • Prevent bronchoconstriction, inflammation, and mucus production in asthma.

    Leukotriene Receptor Antagonists (LTRAs)

    • Mechanism: Block leukotriene receptors.
    • Example: Montelukast (Singulair), Zafirlukast (Accolate).

    5-Lipoxygenase Inhibitors

    • Mechanism: Block 5-lipoxygenase, the enzyme that creates leukotrienes.
    • Example: Zileuton (Zyflo).

    Mast Cell Stabilizers

    • Prevent histamine and other inflammatory mediator release from mast cells involved in allergic reactions.
    • Examples: Cromolyn Sodium (Intal), Nedocromil (Tilade).

    Phosphodiesterase-4 (PDE4) Inhibitors

    • Primarily for severe COPD.
    • Mechanism: Block PDE4, increasing cyclic AMP levels in inflammatory cells to reduce inflammation.
    • Example: Roflumilast (Daliresp).

    Immunomodulators (Biologics)

    • Newer treatments for severe asthma. Target specific immune system components.

    Monoclonal Antibodies

    • Target specific cytokines or immune cells.
    • Examples:
      • Anti-IgE: Omalizumab (Xolair)
      • Anti-IL-5: Mepolizumab (Nucala), Reslizumab
      • Anti-IL-4/IL-13: Dupilumab (Dupixent)

    Additional Notes

    • Important Considerations: Always consult with a healthcare professional before using any medication, especially for long-term use, and be aware of potential side effects.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Explore the various respiratory medications including antihistamines and decongestants. Learn about their mechanisms, effects, types, and examples that are commonly used for treating conditions like allergies and asthma. This quiz provides insights into how these medications work to alleviate respiratory symptoms.

    More Like This

    Respiratory Medications Quiz
    9 questions
    Respiratory Medications Flashcards
    39 questions
    Medications for Upper Respiratory Infections
    68 questions
    Respiratory Medications Overview
    32 questions
    Use Quizgecko on...
    Browser
    Browser