Research Ethics and IRB Process

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Questions and Answers

What is the primary purpose of research ethics?

  • To guide the development of new treatments
  • To protect the human subjects in a study (correct)
  • To evaluate the benefits of a research study
  • To ensure the success of research studies

In the 1700s, who used themselves or their family members as test subjects for vaccination trials?

  • Physicians, including Jenner (correct)
  • Walter Reed and Jenner
  • Volunteers in the yellow fever experiment
  • Jenner and Jorg

What was the outcome of the Nuremberg Trials in relation to research ethics?

  • The ban on human experimentation
  • The establishment of the Institutional Review Board process
  • The identification of 10 basic principles for research ethics (correct)
  • The development of the Declaration of Helsinki

What was the purpose of the Syphilis Study conducted from 1932 to 1971?

<p>To investigate the effects of syphilis on the body over time (C)</p> Signup and view all the answers

What was the significance of the Declaration of Helsinki in 1964?

<p>It prioritized the rights of subjects over scientific research (C)</p> Signup and view all the answers

What was the outcome of the yellow fever experiment led by Walter Reed in the 1900s?

<p>The identification of the risks involved in human experimentation (D)</p> Signup and view all the answers

What is the primary principle of respect for subjects in research?

<p>They should be treated as autonomous beings (B)</p> Signup and view all the answers

What is the purpose of the Belmont Report?

<p>To identify the basic ethical principles that should underlie the conduct of research with human subjects (A)</p> Signup and view all the answers

What is the primary goal of beneficence in research?

<p>To maximize benefits and minimize risks (B)</p> Signup and view all the answers

What is the purpose of a meta-analysis?

<p>To review and synthesize the results of multiple studies (D)</p> Signup and view all the answers

What is the primary advantage of a cohort study?

<p>It is prospective and looks forward in time (C)</p> Signup and view all the answers

What is the primary disadvantage of a case-control study?

<p>It is prone to bias and error (A)</p> Signup and view all the answers

What is the purpose of a systemic review?

<p>To review and synthesize the results of multiple studies (A)</p> Signup and view all the answers

What is the primary advantage of a randomized controlled trial?

<p>It is prospective and randomizes participants to treatment groups (D)</p> Signup and view all the answers

What is the purpose of confounding factors in a study?

<p>To falsely demonstrate an association between variables (B)</p> Signup and view all the answers

What is the purpose of inclusion and exclusion criteria in a study?

<p>To determine who is eligible or not eligible to participate in a study (D)</p> Signup and view all the answers

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