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16 Questions

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Research Ethics and IRB Process

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Questions and Answers

What is the primary purpose of research ethics?

To guide the development of new treatments

To protect the human subjects in a study (correct)

To evaluate the benefits of a research study

To ensure the success of research studies

In the 1700s, who used themselves or their family members as test subjects for vaccination trials?

Physicians, including Jenner (correct)

Walter Reed and Jenner

Volunteers in the yellow fever experiment

Jenner and Jorg

What was the outcome of the Nuremberg Trials in relation to research ethics?

The ban on human experimentation

The establishment of the Institutional Review Board process

The identification of 10 basic principles for research ethics (correct)

The development of the Declaration of Helsinki

What was the purpose of the Syphilis Study conducted from 1932 to 1971?

To investigate the effects of syphilis on the body over time Signup and view all the answers

What was the significance of the Declaration of Helsinki in 1964?

It prioritized the rights of subjects over scientific research Signup and view all the answers

What was the outcome of the yellow fever experiment led by Walter Reed in the 1900s?

The identification of the risks involved in human experimentation Signup and view all the answers

What is the primary principle of respect for subjects in research?

They should be treated as autonomous beings Signup and view all the answers

What is the purpose of the Belmont Report?

To identify the basic ethical principles that should underlie the conduct of research with human subjects Signup and view all the answers

What is the primary goal of beneficence in research?

To maximize benefits and minimize risks Signup and view all the answers

What is the purpose of a meta-analysis?

To review and synthesize the results of multiple studies Signup and view all the answers

What is the primary advantage of a cohort study?

It is prospective and looks forward in time Signup and view all the answers

What is the primary disadvantage of a case-control study?

It is prone to bias and error Signup and view all the answers

What is the purpose of a systemic review?

To review and synthesize the results of multiple studies Signup and view all the answers

What is the primary advantage of a randomized controlled trial?

It is prospective and randomizes participants to treatment groups Signup and view all the answers

What is the purpose of confounding factors in a study?

To falsely demonstrate an association between variables Signup and view all the answers

What is the purpose of inclusion and exclusion criteria in a study?

To determine who is eligible or not eligible to participate in a study Signup and view all the answers