Research Contribution and Funding Acknowledgement

Play an AI-generated podcast conversation about this lesson

What percentage of ingested galactose would be lost if it fully explained the increased food intake, assuming the energy need is the same for both dietary groups and all other nutrients are used completely?

about 40%

What can be inferred from the similar hydrogen production by the gut microbiota in both dietary groups?

A similar amount of nutrients reached the colon and galactose is fully absorbed in the small intestine.

What was the result of the whole genome gene expression analysis in response to galactose in the post-weaning period?

No clear molecular adaptation to galactose, except for a modest upregulation of the Galk2 transcript.

Why may a minor adaptation to galactose be present in mice, despite the lack of significant changes in gene expression?

GALK activity is considered rate limiting in the elimination of galactose from the circulation. Signup and view all the answers

What is the alternative explanation for the efficient metabolism of galactose, despite the lack of significant changes in gene expression?

Regular transcript levels are high enough to allow for an efficient metabolism of galactose. Signup and view all the answers

What is the result of the urinary loss of galactose and concomitant increase in food intake on macronutrient usage?

An altered macronutrient usage, as supported by the lower maximal RER in the GLU+GAL fed females. Signup and view all the answers

What is the role of weaning in the transition from infancy to childhood?

Weaning plays a role in the transition from infancy to childhood, according to the article by Shaoul et al. Signup and view all the answers

What is the importance of digestible dietary carbohydrates in infants and toddlers?

Digestible carbohydrates are essential for infants and toddlers, as they provide energy and support growth and development. Signup and view all the answers

What is the relationship between the timing of complementary feeding and the risk of childhood obesity?

The timing of complementary feeding is associated with the risk of childhood obesity, according to a systematic review by Pearce et al. Signup and view all the answers

Who is the employee of Danone Nutricia Research B.V., according to the author's disclosure?

AO is an employee of Danone Nutricia Research B.V. Signup and view all the answers

What is the role of gut development in infant health?

Gut development is critical in infant health, as it lays the foundation for a healthy digestive system and immune system. Signup and view all the answers

What is the significance of hepatic glycogen synthesis in infant metabolism?

Hepatic glycogen synthesis is an important metabolic process in infants, as it regulates blood sugar levels and energy storage. Signup and view all the answers

What is the main source of carbohydrate in breast milk and infant formula?

Lactose, a disaccharide of the monosaccharides glucose and galactose Signup and view all the answers

How does the intake of galactose change during weaning?

It decreases gradually during weaning Signup and view all the answers

Where is galactose mainly metabolized in the body?

In the liver Signup and view all the answers

What is the significance of galactose elimination from the blood?

It is used as a measure of hepatic function Signup and view all the answers

How does liver glycogen content respond to a glucose bolus versus a galactose bolus in adult rats?

It increases more rapidly after a glucose bolus than after a galactose bolus Signup and view all the answers

Is there an interaction between galactose and glucose metabolism?

Yes Signup and view all the answers

Research Contribution and Funding Acknowledgement

Choose a study mode

Podcast

Questions and Answers