Reproductive Systems and Gametogenesis
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Questions and Answers

What does CRL stand for in the context of embryonic measurements?

  • Crown Radii Length
  • Crown Head Length
  • Crown Heel Length
  • Crown Rump Length (correct)
  • What are the primary germ layers in embryonic development?

  • Neuroectoderm, endoderm, and ectoderm
  • Somites, dermatomes, and myotomes
  • Ectoderm, mesoderm, and endoderm (correct)
  • Epidermis, mesoderm, and neural crest
  • What developmental stage is referred to as a fetus?

  • From the ninth week of pregnancy until birth (correct)
  • From the first week to the eighth week of pregnancy
  • From the moment of conception until birth
  • From the fourth week until the tenth week of pregnancy
  • Which structures are derived from the parasympathetic mesoderm?

    <p>Vertebrae and ribs (B)</p> Signup and view all the answers

    What condition does having only one umbilical artery potentially indicate?

    <p>Increased risk of congenital anomalies (A)</p> Signup and view all the answers

    What is the most likely explanation for bleeding in the last trimester of pregnancy?

    <p>Placental abruption or previa (B)</p> Signup and view all the answers

    How many pairs of somites are present by the end of the fifth week of development?

    <p>44 (D)</p> Signup and view all the answers

    Which component provides the epidermis of the skin?

    <p>Dermoectoderm (B)</p> Signup and view all the answers

    Where is the most common site of ectopic pregnancy implantation?

    <p>Fallopian tube (C)</p> Signup and view all the answers

    What is the role of the intraembryonic celom?

    <p>To give rise to body cavities (B)</p> Signup and view all the answers

    What characterizes the fetal side of the placenta?

    <p>Smooth and covered by amniotic membrane (B)</p> Signup and view all the answers

    What does the lateral plate mesoderm differentiate into?

    <p>Visceral and parietal layers (A)</p> Signup and view all the answers

    What are the primary sex organs responsible for producing gametes in males and females?

    <p>Testes and ovaries (C)</p> Signup and view all the answers

    Which of the following correctly describes the female gamete?

    <p>Secondary oocyte (C)</p> Signup and view all the answers

    What is the average weight of a full-term placenta?

    <p>500 g (D)</p> Signup and view all the answers

    What is the significance of fertilization in terms of chromosomal composition?

    <p>It restores the diploid number of chromosomes (D)</p> Signup and view all the answers

    During which phase of the menstrual cycle does the endometrium thicken in preparation for potential implantation?

    <p>Proliferative phase (D)</p> Signup and view all the answers

    What happens during the cleavage stage of embryonic development?

    <p>Mitosis of the zygote into blastomeres (C)</p> Signup and view all the answers

    Where does fertilization typically occur in the female reproductive system?

    <p>Ampulla of the uterine tube (C)</p> Signup and view all the answers

    Which layer forms the inner lining of the uterus?

    <p>Endometrium (D)</p> Signup and view all the answers

    What chromosomal composition does a typical gamete contain?

    <p>22 autosomes and 1 sex chromosome (D)</p> Signup and view all the answers

    What is the significance of the primitive streak in embryonic development?

    <p>It is the site of gastrulation. (B)</p> Signup and view all the answers

    Which statement correctly describes the notochord?

    <p>It develops from the primitive node. (C)</p> Signup and view all the answers

    What structure replaces the notochord in adult humans?

    <p>Nucleus pulposus (A)</p> Signup and view all the answers

    What marks the changes of the embryonic disc into a cylindrical structure?

    <p>Embryonic folding (A)</p> Signup and view all the answers

    Which germ layer is formed by the displacement of the hypoblast by epiblast cells?

    <p>Endoderm (D)</p> Signup and view all the answers

    What is the role of chorionic villi at the end of the third week?

    <p>To develop into tertiary chorionic villi. (D)</p> Signup and view all the answers

    During the folding of the embryo, which aspect of development is notably modified?

    <p>Formation of the tail and head folds. (B)</p> Signup and view all the answers

    How does the embryonic disc change shape during the third week?

    <p>It elongates with a broad cephalic and narrow caudal end. (A)</p> Signup and view all the answers

    What forms from the outer cells of the morula during the first week of pregnancy?

    <p>Trophoblast (D)</p> Signup and view all the answers

    Where is the common site of implantation in the uterus?

    <p>Upper posterior wall of the fundus (B)</p> Signup and view all the answers

    What is the name of the process where a cavity develops inside the morula during the second week?

    <p>Blastogenesis (A)</p> Signup and view all the answers

    What do the cells of the wall of the umbilical vesicle produce?

    <p>Extraembryonic mesoderm (B)</p> Signup and view all the answers

    What fills the defect left by the embedded blastocyst in the endometrium by the 10th day?

    <p>Closing plug (D)</p> Signup and view all the answers

    What are the two layers formed from the embryoblast during the early stages of the second week?

    <p>Hypoblast and epiblast (B)</p> Signup and view all the answers

    Which layer of the trophoblast develops into the syncytiotrophoblast during the second week?

    <p>Cytotrophoblast (C)</p> Signup and view all the answers

    What signifies the beginning of gastrulation in the development process?

    <p>Formation of the primitive streak (C)</p> Signup and view all the answers

    What is the primary function of the placenta related to metabolism?

    <p>Synthesizing glycogen and fatty acids (B)</p> Signup and view all the answers

    What condition results from abnormal implantation of the placenta inside the endometrium?

    <p>Placenta previa (C)</p> Signup and view all the answers

    What significant change occurs to the placental membrane in the last trimester of pregnancy?

    <p>It reduces to two layers (B)</p> Signup and view all the answers

    What is hydramnios characterized by?

    <p>Excessive amniotic fluid over 1500-2000 ml (C)</p> Signup and view all the answers

    What structure is responsible for maintaining homeostasis of fluid and electrolytes around the embryo?

    <p>Amnion (B)</p> Signup and view all the answers

    Which type of twins originate from two separate zygotes?

    <p>Dizygotic twins (B)</p> Signup and view all the answers

    At full term, what is the approximate length of the umbilical cord?

    <p>50 cm (A)</p> Signup and view all the answers

    What is the expected date of delivery of a fetus calculated from fertilization?

    <p>38 weeks ± 2 weeks (A)</p> Signup and view all the answers

    Flashcards

    Fertilization

    The process by which male and female gametes (sperm and egg) fuse to form a zygote, restoring the diploid number of chromosomes.

    Cleavage (Segmentation)

    The repeated cell division of the zygote, resulting in blastomeres, which are embryonic cells that increase the number of cells without increasing the overall size of the embryo.

    Ovarian Cycle

    The cyclic changes occurring in the ovary every lunar month; it includes three stages - follicular, ovulation, and luteal.

    Menstrual Cycle

    The cyclic changes occurring in the endometrium every lunar month; it includes four phases - menstrual, proliferative, secretory, and ischemic.

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    Primary Sex Organs (Gonads)

    The primary reproductive organs (gonads) that produce gametes. They are the testes in males and the ovaries in females.

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    Gametogenesis

    The conversion of germ cells (diploid with 46 chromosomes) into male and female gametes (haploid with 23 chromosomes).

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    Secondary Oocyte

    The female gamete, which contains 22 autosomes and one X sex chromosome.

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    Sperm

    The male gamete, which contains 22 autosomes and one sex chromosome (either X or Y).

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    Morula

    The ball of cells formed from repeated cell divisions of the zygote during the first week of pregnancy.

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    Trophoblast

    The outer layer of cells surrounding the inner cell mass (embryoblast) of the morula. It plays a critical role in implantation.

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    Blastocyst

    The hollow sphere formed from the morula during the second week of pregnancy. It contains the inner cell mass (embryoblast) and the outer trophoblast.

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    Primitive streak

    A thickened linear band of epiblast cells formed in the caudal aspect of the embryo during the third week of development.

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    Implantation

    The process of the blastocyst embedding itself into the uterine lining (endometrium).

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    Primitive node

    The cranial end of the primitive streak, serving as a signaling center for development.

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    Decidua

    The thickened and modified lining of the uterus during pregnancy. It provides nourishment and protection for the developing embryo.

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    Notochord

    A rod-like structure that forms along the midline of the embryo during the third week, crucial for development of the central nervous system and axial skeleton.

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    Embryonic folding

    The process by which the flat embryonic disc transforms into a cylindrical embryo with a defined head, tail, and body during the fourth week.

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    Epiblast and Hypoblast

    The inner cell mass of the blastocyst splits into two layers: the epiblast (upper layer) and the hypoblast (lower layer).

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    Umbilical ring

    The region where the umbilical cord develops during embryonic folding.

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    Amniotic Cavity

    The fluid-filled sac that surrounds the developing embryo. It forms from the epiblast.

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    Germ layer formation

    The process by which the embryonic disc gives rise to the three primary germ layers: ectoderm, mesoderm, and endoderm.

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    Umbilical Vesicle

    The small sac attached to the yolk sac, which eventually becomes the umbilical cord. It is formed from the hypoblast and the extraembryonic mesoderm.

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    Ectoderm

    The outermost germ layer that gives rise to the skin, nervous system, and sensory organs.

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    Mesoderm

    The middle germ layer that gives rise to muscles, bones, blood, and connective tissues.

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    CRL (Crown-Rump Length)

    The measurement taken from the top of the skull to the center point between the baby's buttocks. Used to assess fetal growth.

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    CHL (Crown-Heel Length)

    The measurement taken from the top of the skull to the heel of the baby. This measure is taken when the baby is in a standing position.

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    Embryo

    The developing human during the first 8 weeks of pregnancy, characterized by rapid growth and development of organ systems.

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    Fetus

    The developing human from the 9th week of pregnancy until birth, characterized by further growth and development of organs and body systems.

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    Congenital Anomalies

    Abnormalities or defects in the development of a baby present at birth. They can range from mild to severe.

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    Umbilical Cord

    The structure that connects the fetus to the placenta, containing two arteries and one vein surrounded by Wharton's jelly.

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    Amnion

    A fluid-filled sac surrounding the embryo, allowing symmetric growth and regulating fluids.

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    Placental Membrane

    The part of the placenta that transfers oxygen and nutrients from the mother to the fetus, while removing waste.

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    Placenta Previa

    The abnormal implantation of the placenta in the lower part of the uterus, potentially causing bleeding during pregnancy.

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    Placenta Accreta

    A rare condition where the placenta attaches too deeply into the uterine wall, potentially leading to complications after birth.

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    Ectopic Pregnancy

    When a fertilized egg implants outside of the uterus, most commonly in the fallopian tube.

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    Dizygotic Twins

    Twins that originate from two separate eggs fertilized by two sperms, making them genetically distinct.

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    Identical Twins

    Twins that originate from a single egg fertilized by a single sperm, making them genetically identical.

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    Somite

    A segmented structure derived from paraxial mesoderm, responsible for forming the vertebrae, ribs, muscles of the back, and dermis of the skin.

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    Sclerotome

    The part of the somite that differentiates into vertebrae, ribs, tendons, and cartilage.

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    Myotome

    The part of the somite that differentiates into muscles of the back and intercostal muscles.

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    Dermatome

    The part of the somite that differentiates into the dermis of the skin.

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    Placenta

    The vital organ that facilitates nutrient and gas exchange between the mother and fetus during pregnancy.

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    Study Notes

    A. Reproductive Systems

    • The female reproductive system comprises two ovaries, two uterine tubes, a uterus, and a vagina.
    • The uterine wall has three layers: endometrium, myometrium, and perimetrium.
    • Fertilization occurs within the uterine tubes.
    • The male reproductive system includes two testes, two epididymis, two seminal vesicles, two ejaculatory ducts, a prostate, and a penis.
    • The primary sex organs (gonads) produce gametes: testes in males and ovaries in females.

    B. Gametogenesis

    • Gametes develop from germ cells that originate in the umbilical vesicle and migrate to the gonads.
    • Gametogenesis transforms germ cells (46 chromosomes, diploid) into male and female gametes (23 chromosomes, haploid).
    • The female gamete is a secondary oocyte (X).
    • The male gamete is a sperm (X or Y).
    • Gametes contain 22 autosomes and one sex chromosome.
    • Errors in meiosis can lead to abnormal gametes, such as in Down syndrome.

    C. Female Reproductive Cycles

    • The ovarian cycle involves cyclical changes in the ovary monthly.
    • The menstrual cycle involves cyclical changes in the endometrium monthly.
    • The ovarian cycle phases are follicular, ovulation, and luteal.
    • The menstrual cycle phases are ischemic, menstrual, proliferative, and luteal.
    • Breastfeeding can temporarily cease menstruation.

    D. Fertilization

    • Fertilization is the fusion of male and female gametes to form a zygote.
    • Fertilization typically occurs in the ampulla of the uterine tube.
    • Fertilization restores the diploid chromosome number (46 chromosomes).
    • Fertilization determines the embryo's sex (XX or XY).
    • Embryonic age begins two weeks after the last normal menstrual period (LNMP).

    E. Cleavage (Segmentation)

    • Cleavage involves repeated mitotic divisions of the zygote, producing blastomeres.
    • Cleavage occurs in the uterine tube during the first week of pregnancy.
    • The morula is a solid ball of cells formed during cleavage.
    • The morula develops into a blastocyst with an inner cell mass (embryoblast) and outer layer (trophoblast).

    F. Implantation

    • Implantation is the embedding of the blastocyst into the endometrium of the uterus.
    • The usual implantation site is the upper posterior wall of the uterus's fundus.
    • By day 10, the blastocyst is fully embedded, creating a closing plug within the endometrium.
    • By the end of the second week, the endometrium is filled with edematous cells rich in glycogen and lipids (decidua).

    G. Gastrulation

    • Gastrulation is the beginning of morphogenesis (body form development), occurring during week 3.
    • The first sign of gastrulation is the primitive streak formation, a thickened linear band of epiblast cells.
    • The primitive node is at the cranial end of the primitive streak.
    • The primitive streak's growth leads to the development of the notochord.

    H. The 3rd Week

    • The notochordal process forms a plate, which folds to form the notochord, the primordial axis of the embryo.
    • The notochord is crucial for central nervous system and axial musculoskeletal development.
    • The end of the 3rd week finds the embryonic disc changing shape to a flat, elongated form with a broad head and narrow tail.
    • Tertiary chorionic villi form during this period.

    I. Folding of the Embryo

    • During the fourth week, the flat embryonic disc folds to form a cylindrical embryo.
    • Folding involves the formation of a head, tail, and lateral folds, resulting in the umbilical ring.
    • The chorionic villi at the embryonic pole grow and branch, forming the chorion frondosum part of the placenta.

    J. Derivatives of the Germ Layers

    • The epiblast forms the three germ layers (ectoderm, mesoderm, endoderm).
    • The ectoderm differentiates into neuroectoderm and dermoectoderm.
    • The neuroectoderm gives rise to the neural tube and crest.
    • The mesoderm is segmented into paraxial, intermediate, and lateral plate mesoderms.
    • The paraxial mesoderm forms somites, crucial for skeletal, muscular and connective tissue development.
    • The number of somites can be used to determine the embryo's age.
    • The intermediate mesoderm contributes to the urogenital system.
    • The lateral plate mesoderm forms the intraembryonic coelom and subsequently the pericardial, pleural and peritoneal cavities.

    K. Placenta

    • The placenta is the fetal-maternal organ responsible for gas and nutrient exchange.
    • The full-term placenta is discoid, weighing approximately 500g and expelled within 30 minutes of birth.
    • The fetal side of the placenta, derived from the chorion frondosum, is smooth and covered by the amnion.
    • The maternal side, derived from the decidua basalis, is irregular and divided into cotyledons.

    L. Umbilical Cord

    • The umbilical cord is about 50 cm long at full term.
    • The cord contains two arteries and one vein, enveloped in Wharton's jelly.

    M. Twins

    • Dizygotic twins arise from two separate zygotes.
    • Monozygotic twins arise from one zygote.
    • Conjoined twins result from incomplete separation.

    THE Amnion

    • The amnion forms a fluid-filled sac that surrounds the embryo, maintaining homeostasis and supporting growth.
    • Amniotic fluid volume varies but typically 800-1000ml.
    • The umbilical vesicle, an older name for the yolk sac, is a pear-shaped structure connected to the midgut by a duct. It plays a role in germ cell development.

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    Description

    This quiz explores the anatomy and functions of the male and female reproductive systems, including gametogenesis and the processes involved in the formation of gametes. Additionally, it will cover the structure of the ovarian and menstrual cycles. Test your knowledge on the biological aspects of reproduction!

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