Reproductive System Overview and Male Anatomy

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Questions and Answers

What is the primary function of the proximal convoluted tubule (PCT)?

  • Filtering blood plasma from the glomerular capillaries
  • Reabsorbing organic nutrients and ions from tubular fluid (correct)
  • Secreting metabolic wastes into urine
  • Transporting urine to the urinary bladder

Which of the following metabolic wastes is NOT formed from the breakdown of amino acids?

  • Lactic acid (correct)
  • Urea
  • Creatinine
  • Uric acid

Where does urine transport begin in the urinary system?

  • Ureters (correct)
  • Urethra
  • Urinary bladder
  • Renal pelvis

What is the purpose of the structures known as podocytes in the glomerular capsule?

<p>To create a filtration barrier around capillaries (B)</p> Signup and view all the answers

Which part of the urinary bladder is responsible for involuntary control of urination?

<p>Internal urethral sphincter (B)</p> Signup and view all the answers

What causes a painful condition known as nephrolithiasis?

<p>Presence of kidney stones (C)</p> Signup and view all the answers

What key function do the juxtaglomerular cells serve in the kidneys?

<p>Regulation of blood pressure (A)</p> Signup and view all the answers

Which layer of the ureters is primarily responsible for peristalsis?

<p>Middle smooth muscle layer (A)</p> Signup and view all the answers

Which component is found in urine but not involved in the reabsorption process in the PCT?

<p>Creatinine (C)</p> Signup and view all the answers

What structure forms the outer wall of the renal corpuscle?

<p>Glomerular capsule (C)</p> Signup and view all the answers

What is the primary function of the testes in the male reproductive system?

<p>To produce gametes and hormones (D)</p> Signup and view all the answers

Which structure acts as a site for sperm maturation and storage?

<p>Epididymis (C)</p> Signup and view all the answers

What is the primary role of the interstitial cells (Leydig cells) within the testes?

<p>Producing male sex hormones (C)</p> Signup and view all the answers

How do the seminal glands contribute to semen?

<p>By providing 60% of the total semen fluid (D)</p> Signup and view all the answers

What function do the dartos and cremaster muscles serve in the male reproductive system?

<p>Regulate testis temperature (C)</p> Signup and view all the answers

What is the pathway of sperm from the testes to the urethra?

<p>Epididymis → Ductus deferens → Urethra (B)</p> Signup and view all the answers

Which gland surrounds the urethra and produces a slightly acidic fluid?

<p>Prostate gland (D)</p> Signup and view all the answers

What is the role of Sertoli cells within the seminiferous tubules?

<p>Nourishing developing sperm (A)</p> Signup and view all the answers

What is the significance of semen being slightly alkaline?

<p>Helps neutralize acidity in the vagina (D)</p> Signup and view all the answers

What is the approximate length of the male urethra?

<p>18-20 cm (C)</p> Signup and view all the answers

What role does the bulbo-urethral gland play in semen production?

<p>It produces thick alkaline mucus that helps neutralize acids. (A)</p> Signup and view all the answers

Which statement accurately describes the process of oogenesis?

<p>It begins after birth and continues until menopause. (C)</p> Signup and view all the answers

What occurs during the luteal phase of the ovarian cycle?

<p>The corpus luteum secretes progesterone for endometrial preparation. (A)</p> Signup and view all the answers

How does the erectile tissue of the penis function during an erection?

<p>Parasympathetic neurons induce arterial dilation and increased blood flow. (A)</p> Signup and view all the answers

What triggers the release of FSH and LH in males?

<p>GnRH released by the hypothalamus. (B)</p> Signup and view all the answers

Which hormone is primarily responsible for preparing the endometrium for implantation?

<p>Progesterone (C)</p> Signup and view all the answers

What is the main function of the fimbriae in the uterine tubes?

<p>Help propel the oocyte into the uterine tube after ovulation. (B)</p> Signup and view all the answers

Which structure in the kidney is responsible for filtering blood?

<p>Glomerulus (D)</p> Signup and view all the answers

What is the primary role of the urethra in the urinary system?

<p>To carry urine from the bladder to the exterior. (D)</p> Signup and view all the answers

How do hormonal changes control the male reproductive cycle?

<p>FSH and LH regulate spermatogenesis and testosterone release. (C)</p> Signup and view all the answers

What physical changes occur during menopause?

<p>A decline in estrogens and progesterone occurs. (A)</p> Signup and view all the answers

What is the primary component of the uterine cycle that is shed during menstruation?

<p>Functional zone of the endometrium (D)</p> Signup and view all the answers

What is the role of the suspensory ligament in the female reproductive system?

<p>It contains blood vessels supplying the ovaries. (D)</p> Signup and view all the answers

Which phase follows ovulation in the ovarian cycle?

<p>Luteal phase (D)</p> Signup and view all the answers

What is the term for the solution produced following the filtration process in the renal corpuscle?

<p>Filtrate (A)</p> Signup and view all the answers

Which structure follows the proximal convoluted tubule in the flow of filtrate?

<p>Nephron loop (A)</p> Signup and view all the answers

What type of capillaries are located within the renal corpuscle?

<p>Glomerulus (A)</p> Signup and view all the answers

In which part of the nephron does the tubular fluid begin to be recognized as urine?

<p>Collecting duct (A)</p> Signup and view all the answers

What is the first vessel to receive blood after it has passed through the afferent arteriole?

<p>Glomerulus (D)</p> Signup and view all the answers

What structures drain urine from the renal papilla into the minor calyx?

<p>Ducts (D)</p> Signup and view all the answers

Which component serves as the point of entry and exit for blood vessels and nerves in the kidneys?

<p>Hilum (C)</p> Signup and view all the answers

What is the structure that combines 2–3 major calyces in the renal system?

<p>Renal pelvis (D)</p> Signup and view all the answers

What is the primary anatomical structure that projects into the renal sinus from the tip of the renal pyramid?

<p>Renal papilla (D)</p> Signup and view all the answers

How many nephrons are approximately present in each human kidney?

<p>1.25 million (B)</p> Signup and view all the answers

What is the primary role of podocytes in the filtration membrane of the nephron?

<p>They form filtration slits for blood filtration. (A)</p> Signup and view all the answers

Which structure directly contributes to the formation of the basement membrane in the glomerulus?

<p>Endothelial cells of capillaries. (B)</p> Signup and view all the answers

What are filtration slits and where are they located?

<p>They are gaps between podocyte processes in the filtration membrane. (B)</p> Signup and view all the answers

Which component is NOT a part of the filtration membrane in the nephron?

<p>Red blood cells (C)</p> Signup and view all the answers

Which structure supports the filtering function of the glomerulus?

<p>The pliability of the basement membrane. (D)</p> Signup and view all the answers

What is the primary role of the renal corpuscle?

<p>Produce filtrate through a passive process (A)</p> Signup and view all the answers

Which structure encloses the glomerular capillaries in the renal corpuscle?

<p>Glomerular capsule (A)</p> Signup and view all the answers

What is the role of podocytes in the kidney?

<p>Filter blood plasma (B)</p> Signup and view all the answers

What happens to over 90 percent of water during the nephron's tubular reabsorption?

<p>It is reabsorbed back into the blood (D)</p> Signup and view all the answers

What type of fluid flow is illustrated in the nephron structure?

<p>Tubular fluid flow (C)</p> Signup and view all the answers

What type of epithelium forms the outer layer of the glomerular capsule?

<p>Capsular epithelium (B)</p> Signup and view all the answers

Which nephron structure allows for variable solute reabsorption or secretion?

<p>Collecting duct (C)</p> Signup and view all the answers

What is the function of the nephron loop in the kidney?

<p>Reabsorb water and create a concentration gradient (C)</p> Signup and view all the answers

What is the primary function of the ureters?

<p>Conduct urine from kidneys to urinary bladder (B)</p> Signup and view all the answers

What is a characteristic of kidney stones?

<p>May reduce or prevent filtration (D)</p> Signup and view all the answers

Which muscle layer moves urine through the ureter by peristalsis?

<p>Smooth muscle layer (C)</p> Signup and view all the answers

What forms the triangular area known as the trigone in the urinary bladder?

<p>Two ureteral openings and urethral entrance (C)</p> Signup and view all the answers

What type of epithelium lines the inner layer of the ureter wall?

<p>Transitional epithelium (C)</p> Signup and view all the answers

What is the main function of the distal convoluted tubule in the nephron?

<p>Active secretion of ions and toxins (D)</p> Signup and view all the answers

What is the length of the female urethra approximately?

<p>2.5–3.0 cm (C)</p> Signup and view all the answers

Which structure contains the involuntary internal urethral sphincter?

<p>Neck of bladder (B)</p> Signup and view all the answers

What is the primary permeability characteristic of the descending limb of the nephron loop?

<p>Permeable only to water (C)</p> Signup and view all the answers

What is the primary role of the detrusor muscle in the urinary bladder?

<p>Expel urine into the urethra (B)</p> Signup and view all the answers

How does the proximal convoluted tubule contribute to the regulation of body fluids?

<p>Reabsorbs a majority of filtration volume and nutrients (C)</p> Signup and view all the answers

What occurs in the ascending limb of the nephron loop?

<p>Solutes are reabsorbed while water remains (C)</p> Signup and view all the answers

What type of epithelium lines the glomerular capsule?

<p>Simple squamous epithelium (D)</p> Signup and view all the answers

What is the primary role of the macula densa cells?

<p>Detecting changes in sodium concentration (B)</p> Signup and view all the answers

In which section of the nephron does the majority of water reabsorption occur?

<p>Proximal convoluted tubule (C)</p> Signup and view all the answers

What is the function of the juxtaglomerular cells?

<p>Secrete hormones to regulate blood pressure (C)</p> Signup and view all the answers

Flashcards

Male Reproductive System Function

Produces, stores, nourishes, and transports sperm (male reproductive cells).

Testes Location

Held outside the body in the scrotum to regulate temperature for sperm production.

Seminiferous Tubules

Coiled tubes inside testes where sperm are produced.

Leydig Cells

Produce testosterone (male hormone) in the testes.

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Epididymis Function

Stores sperm, adjusts fluid, and completes sperm maturation; important for sperm movement later.

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Ductus Deferens

Tube that transports sperm from the epididymis to the ejaculatory duct.

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Semen Composition

Mixture of sperm and fluids from accessory glands (nourishment and protection).

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Accessory Glands

Produce the fluid part of semen that nourishes and protects sperm during ejaculation.

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Seminal Vesicles

Produce a significant portion of semen fluid containing nutrients and other components, such as fructose for energy.

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Prostate Gland

Produces fluids that help to activate and transport sperm.

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Glomerular Capsule

Outer wall of the renal corpuscle; encloses glomerular capillaries.

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Podocytes

Cells in the visceral layer of the glomerular capsule with foot processes (pedicels) wrapping around capillaries.

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Urea

Most abundant waste product; formed from amino acid breakdown.

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Creatinine

Waste created from skeletal muscle creatine phosphate breakdown.

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Ureters

Paired tubes transporting urine from kidneys to bladder; prevent backflow.

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Kidney Stones

Solid substances (calculi) formed from calcium, magnesium, or uric acid crystals.

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Urinary Bladder

Stores urine; size varies with contents, holds up to 1 liter.

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Trigone

Triangle at the base of the bladder, with ureteral openings and urethra.

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Proximal Convoluted Tubule (PCT)

First segment of renal tubule; majority of reabsorption occurs here.

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Collecting System

Network of ducts that transports tubular fluid to the renal pelvis for adjusting fluid composition and osmotic concentration.

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Bulbourethral glands

Paired glands near the base of the penis that secrete an alkaline mucus to neutralize acids and lubricate the glans penis. Produces less than 5% of semen.

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Spermatozoa count

Normal sperm count in semen is 20-100 million per milliliter.

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Ejaculate volume

Typical ejaculation volume is 2-5 mL of semen.

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Penis function

The penis introduces semen into the vagina during intercourse and conducts urine out of the body.

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Prepuce (foreskin)

A fold of skin covering the glans penis; often removed in circumcision.

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Circumcision benefit

Circumcision can lower the risk of UTIs, penile cancer, and HIV infection.

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Erection mechanism

During erection, nitric oxide (NO) relaxes smooth muscles, causing dilation of arteries and filling of vascular channels with blood.

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Spermatogenesis

The process of sperm cell production within the testes.

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Oogenesis

The process of ovum production in the ovaries beginning before birth.

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Ovarian Cycle

A 28-day cycle of follicle development, ovulation, and corpus luteum formation.

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Follicular Phase

The preovulatory phase of the ovarian cycle, involving follicle growth stimulated by FSH.

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Ovulation

Release of a secondary oocyte from the follicle.

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Luteal Phase

The postovulatory phase, involving corpus luteum formation (progesterone secretion).

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Uterine cycle

Series of changes in the uterine lining (endometrium) throughout the menstrual cycle.

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Renal Capsule

A tough, fibrous membrane that surrounds the kidney, protecting it and maintaining its shape.

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Renal Cortex

The outer layer of the kidney containing the nephrons, responsible for filtering blood and producing urine.

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Renal Medulla

The inner layer of the kidney containing the renal pyramids, responsible for collecting and transporting urine.

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Renal Pyramid

Cone-shaped structures within the renal medulla that contain collecting tubules, responsible for concentrating urine.

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Renal Papilla

The tip of each renal pyramid that projects into the renal sinus, allowing urine to drain into the minor calyx.

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What is the renal corpuscle?

A spherical structure that filters blood in the nephron. It consists of the glomerulus (a capillary network) and the Bowman's capsule, which surrounds the glomerulus.

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What is the function of the glomerulus?

The glomerulus is a network of capillaries in the renal corpuscle. It acts as a filter, allowing blood to pass through its walls but retaining large molecules like blood cells and proteins.

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What are the segments of the renal tubule?

The renal tubule is a long, twisted tube that carries filtrate from the renal corpuscle. It's divided into three sections: the proximal convoluted tubule (PCT), the nephron loop (or loop of Henle), and the distal convoluted tubule (DCT).

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What is the difference between filtrate and tubular fluid?

Filtrate is the fluid that has been filtered from the blood in the glomerulus. As it moves through the renal tubule, its composition is altered, and it's then called tubular fluid.

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What is the role of the collecting duct?

The collecting duct is the final segment of the nephron. It collects tubular fluid from multiple nephrons and transports it to the renal pelvis. It also plays a crucial role in adjusting the composition of urine by regulating water reabsorption.

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Filtration Membrane

A multi-layered structure in the glomerulus that filters blood, allowing small molecules to pass through but blocking larger molecules like blood cells and proteins.

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Filtration Slits

Gaps between the pedicels of podocytes, allowing small molecules to pass through but blocking larger molecules.

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Basement Membrane

A layer of the filtration membrane made of collagen and glycoproteins, providing structural support and filtering blood.

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What is the glomerulus?

A network of capillaries within the renal corpuscle that acts as a filter for blood, allowing small molecules like water, glucose, and ions to pass through but blocking large molecules like blood cells and proteins.

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Renal Corpuscle Function

The renal corpuscle filters blood, creating a filtrate that contains valuable nutrients, ions, and water.

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Glomerulus

A network of capillaries within the renal corpuscle where filtration occurs. Blood pressure forces fluids and small solutes into the capsular space.

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Nephron Loop Function

Responsible for reabsorbing water and ions from the filtrate, contributing to concentration gradients in the medulla.

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Proximal Convoluted Tubule (PCT) Function

The first part of the renal tubule, where most reabsorption of water, nutrients, and ions from the filtrate back into the blood occurs.

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Collecting Duct Function

Carries tubular fluid from the nephrons, adjusts fluid composition and osmotic concentration, and ultimately delivers urine to the renal pelvis.

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What are the three main parts of the nephron?

The nephron consists of the renal corpuscle, the renal tubule, and the collecting duct.

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What is the purpose of the nephron?

Nephrons are the functional units of the kidneys, responsible for filtering blood, reabsorbing essential substances, and secreting waste products to produce urine.

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Uric acid

A waste product formed from the breakdown and recycling of RNA.

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Detrusor muscle

The smooth muscle layer in the urinary bladder wall that contracts to expel urine into the urethra.

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Glomerular Capillary

A network of capillaries within the glomerulus, responsible for filtering blood by allowing passage of water, small solutes, and waste products while retaining larger molecules like blood cells and proteins.

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Nephron Loop (Loop of Henle)

A U-shaped segment of the renal tubule following the PCT, playing a crucial role in concentrating urine through countercurrent multiplication, where water is reabsorbed in the descending limb and solutes are reabsorbed in the ascending limb.

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Distal Convoluted Tubule (DCT)

The final segment of the renal tubule before the collecting duct, involved in regulating the fine-tuning of electrolyte balance, acid-base balance, and hormone-mediated reabsorption of sodium and calcium.

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Juxtaglomerular Complex

A specialized region where the distal convoluted tubule contacts the afferent and efferent arterioles, playing a key role in regulating blood pressure and filtration rate by releasing renin, a hormone that triggers the renin-angiotensin-aldosterone system.

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Macula Densa

A specialized group of cells in the distal convoluted tubule that monitor the sodium concentration in the tubular fluid, providing feedback to the juxtaglomerular cells, which release renin to control blood pressure and glomerular filtration rate.

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Study Notes

Reproductive System Overview

  • The reproductive system produces, stores, nourishes, and transports gametes (reproductive cells)
  • Structures include gonads, ducts, accessory glands, and external genitalia
  • Gonads produce gametes and hormones
  • Ducts receive and transport gametes
  • Accessory glands secrete fluids into ducts
  • External genitalia are the external reproductive structures

Male Reproductive System

  • Gametes (sperm): Produced in the testes. Testes also produce androgens (primarily testosterone). Sperm combines with secretions from accessory glands to form semen.
  • Ducts: Sperm travels through the epididymis, ductus deferens, ejaculatory duct, and urethra.
  • Accessory organs: Seminal glands, prostate gland, and bulbourethral glands secrete fluids into the ejaculatory ducts and urethra.
  • External genitalia: Scrotum and penis

Male Reproductive System: Testes and Scrotum

  • Testes are about 5 cm long, 3 cm wide, and 2.5 cm thick.
  • Held outside the body in the scrotum.
  • Scrotum is divided into two chambers, each holding a testis.
  • Dartos and cremaster muscles regulate testis temperature.
  • Each testis has a fibrous capsule called the tunica albuginea.

Male Reproductive System: Internal Structure of Testes

  • Collagen fibers extend into the testis, forming septa.
  • Testes divided into about 250 lobules.
  • Seminiferous tubules are tightly coiled within each lobule; site of spermatogenesis (sperm production).
  • Tubules contain nurse cells (Sertoli cells) that nourish developing sperm.
  • Sperm passes through rete testis into efferent ductules to epididymis.

Male Reproductive System: Interstitial Cells

  • Also called Leydig cells
  • Located in spaces between seminiferous tubules
  • Produce male sex hormones (androgens), with testosterone as the most important

Male Reproductive System: Epididymis

  • Coiled tube attached to the posterior portion of the testis.
  • Adjusts fluid composition produced by seminiferous tubules
  • Recycles damaged spermatozoa
  • Stores and protects maturing spermatozoa.

Male Reproductive System: Ductus Deferens

  • Also called the vas deferens
  • Spermatozoa and fluid propelled along it by peristalsis.
  • Passes through the inguinal canal, into the abdominal cavity within the spermatic cord.
  • Passes laterally to the urinary bladder.
  • Curves down past ureters toward the prostate gland.
  • Expanded distal portion called the ampulla. Sperm can be stored here for several months.

Male Reproductive System: Accessory Glands

  • Includes seminal glands, prostate gland, and bulbourethral glands.
  • Produce fluid component of semen
  • Activate spermatozoa
  • Provide nutrients for motility.
  • Generate peristaltic contractions to propel sperm and semen.
  • Produce buffers to counteract acidic environment of urethra and vagina

Male Reproductive System: Seminal Glands

  • Also called seminal vesicles
  • Contribute 60% of semen fluid
  • Secretion is slightly alkaline to neutralize acids.
  • Secretions contain fructose, prostaglandins, and fibrinogen

Male Reproductive System: Prostate Gland

  • Small, round, muscular organ
  • Surrounds urethra as it leaves the urinary bladder
  • Produces prostatic fluid (slightly acidic). - Makes up about 20-30% of semen.
  • Contains seminalplasmin (protein with antibiotic properties).
  • Peristaltic contractions help propel secretions into urethra

Male Reproductive System: Bulbo-Urethral Glands

  • Also called Cowper's glands
  • Paired glands located at the base of the penis.
  • Contribute less than 5% of semen
  • Secrete thick alkaline mucus.
  • Helps neutralize urinary acids
  • Lubricates the glans penis

Male Reproductive System: Semen

  • Fluid containing sperm and secretions of accessory glands.
  • Typical ejaculate expels 2-5 mL of semen

Male Reproductive System: Penis

  • Tubular organ containing distal portion of urethra
  • Introduces semen to vagina during intercourse.
  • Also conducts urine to the exterior through urethra.
  • Three main regions: Root, Body, and Glans.

Male Reproductive System: Prepuce and Circumcision

  • Prepuce (foreskin)-fold of skin over glans penis
  • Preputial glands secrete smegma
  • Can be a nutrient source for bacteria
  • Circumcision is the surgical removal of prepuce

Male Reproductive System: Erectile Tissue of the Penis

  • Maze of vascular channels with incomplete partitions.
  • Corpus spongiosum surrounds urethra
  • In resting state, little blood flow; arterial branches restricted.
  • During erection, parasympathetic neurons release nitric oxide (NO), smooth muscles in arterial walls relax, vessels dilate, and channels fill with blood.

Male Reproductive System: Male Reproductive Hormones

  • GnRH (gonadotropin-releasing hormone) secreted by hypothalamus triggers release of FSH and LH from anterior pituitary
  • FSH targets cells to trigger spermatogenesis
  • LH causes interstitial cells to secrete testosterone

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