Reproductive Development and Hormones
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Questions and Answers

What is the mechanism by which LH stimulates progesterone secretion in the corpus luteum?

  • Inhibition of protein synthesis and subsequent activation of adenylyl cyclase
  • Activation of adenylyl cyclase and subsequent protein synthesis (correct)
  • Inhibition of adenylyl cyclase and subsequent reduction of protein synthesis
  • Stimulation of phosphodiesterase and subsequent reduction of cAMP

What is the effect of progesterone on the myometrial cells?

  • Increases their excitability and sensitivity to oxytocin
  • Increases their membrane potential and spontaneous electrical activity
  • Decreases their excitability and sensitivity to oxytocin (correct)
  • Has no effect on their excitability and sensitivity to oxytocin

What is the effect of progesterone on estrogen receptors in the endometrium?

  • Decreases their number and activity (correct)
  • Increases their number and activity
  • Increases their number but decreases their activity
  • Has no effect on their number and activity

What is the role of progesterone in the breast during lactation?

<p>Induces differentiation of estrogen-prepared ductal tissue (C)</p> Signup and view all the answers

What is the effect of large doses of progesterone on LH secretion?

<p>Inhibits LH secretion (C)</p> Signup and view all the answers

What is the physiological effect of progesterone in terms of body temperature?

<p>Increases basal body temperature (A)</p> Signup and view all the answers

What triggers the initiation of lactation after delivery in women?

<p>Abrupt decline in circulating estrogens and progesterone (C)</p> Signup and view all the answers

Why do women who do not wish to breastfeed their babies receive estrogen administration?

<p>To stop lactation and milk production (C)</p> Signup and view all the answers

What is the primary effect of estrogen on milk production in women?

<p>It antagonizes the milk-producing effect of prolactin on the breast (D)</p> Signup and view all the answers

What is the primary stimulus for milk ejection and oxytocin release in women?

<p>Suckling and reflex stimulation (B)</p> Signup and view all the answers

What is the composition of colostrum compared to milk?

<p>It contains the same concentration of protein and lactose but no fat as in milk (B)</p> Signup and view all the answers

How long does it take for milk secretion to surge after delivery in women?

<p>Within 1-3 days after delivery (C)</p> Signup and view all the answers

What is the primary difference between the reproductive system of men and women?

<p>Women's reproductive systems show regular cyclic changes (B)</p> Signup and view all the answers

What is the average length of a menstrual cycle in women?

<p>28 days (D)</p> Signup and view all the answers

What is the term for the periodic vaginal bleeding that occurs with the shedding of the uterine mucosa?

<p>Menstruation (A)</p> Signup and view all the answers

What is the primary cause of male sexual behavior and pattern of gonadotropin secretion in some species?

<p>The action of male hormones on the brain in early development (B)</p> Signup and view all the answers

What is the function of the antrum in the ovarian cycle?

<p>To fill with follicular fluid (D)</p> Signup and view all the answers

What is the role of gonadotropins from the anterior pituitary in reproductive development?

<p>To activate the gonads during adolescence (A)</p> Signup and view all the answers

What is the term for the decline in the function of the testes with advancing age?

<p>Andropause (B)</p> Signup and view all the answers

What is the effect of hormones secreted by the gonads during adolescence?

<p>The appearance of features typical of the adult male or female (C)</p> Signup and view all the answers

What is the pattern of ovarian function in human females?

<p>It regresses after a number of years (A)</p> Signup and view all the answers

What is the purpose of the cyclic changes in the female reproductive system?

<p>To prepare for pregnancy and fertilization (B)</p> Signup and view all the answers

What is the dual function of the gonads in both sexes?

<p>The production of germ cells and the secretion of sex hormones (B)</p> Signup and view all the answers

What is the pattern of androgen secretion in the ovaries compared to the testes?

<p>The ovaries secrete small amounts of androgens, while the testes secrete large amounts (D)</p> Signup and view all the answers

At what age range does menopause typically occur?

<p>Between 45 and 55 (C)</p> Signup and view all the answers

What percentage of menopausal women experience hot flushes?

<p>75% (C)</p> Signup and view all the answers

What is the cause of hot flushes in menopausal women?

<p>Unknown (D)</p> Signup and view all the answers

What is prevented by estrogen treatment in menopausal women?

<p>Hot flushes (A)</p> Signup and view all the answers

What initiates both the release of LH and the episode of flushing in menopausal women?

<p>Hypothalamus (C)</p> Signup and view all the answers

What is the approximate age range during which menopause typically occurs?

<p>45-55 years (B)</p> Signup and view all the answers

Which hormone is released in episodic bursts at intervals of 30-60 minutes or more during menopause?

<p>LH (B)</p> Signup and view all the answers

What is the percentage of menopausal women who experience hot flushes?

<p>75% (B)</p> Signup and view all the answers

What is the event that initiates both the release of LH and the episode of flushing in menopausal women?

<p>Some estrogen-sensitive event in the hypothalamus (A)</p> Signup and view all the answers

What is the average age at which menopause typically occurs?

<p>52 years (C)</p> Signup and view all the answers

What is the duration for which hot flushes may continue intermittently in menopausal women?

<p>40 years (C)</p> Signup and view all the answers

What is the primary function of the reduction in membrane potential of the ovum after fertilization?

<p>To prevent polyspermy (C)</p> Signup and view all the answers

What is the structural change that occurs in the zona pellucida after fertilization?

<p>It undergoes a change that provides long-term protection against polyspermy (D)</p> Signup and view all the answers

How long does it take for the blastocyst to reach the uterus after fertilization?

<p>3 days (B)</p> Signup and view all the answers

What is the term for the multi-nucleate mass that surrounds the blastocyst after it reaches the uterus?

<p>Syncytiotrophoblast (A)</p> Signup and view all the answers

What is the usual site of implantation of the blastocyst in the uterus?

<p>Dorsal wall (A)</p> Signup and view all the answers

What develops from the trophoblast after implantation?

<p>Placenta (B)</p> Signup and view all the answers

What is the primary function of the corpus luteum during pregnancy?

<p>To secrete estrogens, progesterone, and relaxin, and maintain pregnancy (D)</p> Signup and view all the answers

What hormone secreted by the placenta takes over the function of the corpus luteum after the sixth week of pregnancy?

<p>Estrogen (B)</p> Signup and view all the answers

What is the composition of human chorionic gonadotropin (hCG)?

<p>A glycoprotein containing galactose and hexosamine (A)</p> Signup and view all the answers

What is the effect of progesterone on the uterus during pregnancy?

<p>It inhibits myometrial contractions and prevents prostaglandin production (D)</p> Signup and view all the answers

When does the function of the corpus luteum begin to decline during pregnancy?

<p>After 8 weeks of pregnancy (C)</p> Signup and view all the answers

What is the pattern of human chorionic gonadotropin (hCG) secretion during pregnancy?

<p>It decreases after an initial marked rise (B)</p> Signup and view all the answers

What is the function of LH receptors in theca interna cells?

<p>To convert cholesterol to androstenedione (D)</p> Signup and view all the answers

What is the primary function of granulosa cells in the ovarian cycle?

<p>To convert androstenedione to estradiol (D)</p> Signup and view all the answers

What percentage of circulating estradiol is free?

<p>2% (B)</p> Signup and view all the answers

What is the fate of estradiol, estrone, and estriol in the liver?

<p>They are converted to glucuronide and sulfate conjugates (D)</p> Signup and view all the answers

What is the significance of enterohepatic circulation in the metabolism of estradiol?

<p>It recycles estradiol metabolites back into the bloodstream (D)</p> Signup and view all the answers

What is the role of FSH in granulosa cells?

<p>To increase the secretion of estradiol (D)</p> Signup and view all the answers

What is the typical duration of amenorrhea in women who breastfeed regularly?

<p>25-30 weeks (D)</p> Signup and view all the answers

What is the effect of prolactin on GnRH secretion?

<p>Inhibition (C)</p> Signup and view all the answers

What percentage of women become pregnant again during the suckling period?

<p>5-10% (B)</p> Signup and view all the answers

What is the percentage of anovulatory cycles in the first 6 months after resumption of menses?

<p>almost 50% (A)</p> Signup and view all the answers

What is the primary function of the gonads in both sexes?

<p>Dual function of production of germ cells and secretion of sex hormones (B)</p> Signup and view all the answers

What is the difference between males and females that depends primarily on a single chromosome?

<p>The presence of a Y chromosome (A)</p> Signup and view all the answers

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