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Questions and Answers
¿Qué complejo hormona-receptor modula la diferenciación de los genitales externos masculinos?
¿Qué complejo hormona-receptor modula la diferenciación de los genitales externos masculinos?
- Complejo testosterona/receptor
- Complejo estrógeno/receptor
- Complejo progesterona/receptor
- Complejo dihidrotestosterona/receptor (correct)
¿Qué células se originan en el epiblasto y migran a las gónadas en la quinta semana de desarrollo?
¿Qué células se originan en el epiblasto y migran a las gónadas en la quinta semana de desarrollo?
- Células somáticas
- Células nerviosas
- Células musculares
- Células germinales primordiales (correct)
¿Qué gen influye en la proliferación y penetración de los cordones testiculares en la médula para formar los testÃculos?
¿Qué gen influye en la proliferación y penetración de los cordones testiculares en la médula para formar los testÃculos?
- Gen SOX9
- Gen WNT4
- Gen SRY (correct)
- Gen FOXL2
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Study Notes
- Testosterone and dihydrotestosterone bind to specific intracellular protein receptors.
- This hormone-receptor complex binds to DNA to regulate tissue-specific gene transcription.
- Testosterone/receptor complex modulates the virilization of mesonephric ducts.
- Dihydrotestosterone/receptor complex modulates the differentiation of male external genitalia.
- Gonads are undifferentiated until after the 7th week of development.
- Primordial germ cells originate in the epiblast and migrate to the gonads in the 5th week.
- Male gonads proliferate and penetrate the medulla to form testicular cords under the influence of the SRY gene.
- Testicular cords divide into small networks to form the testis.
- The testicular cords are separated from the surface epithelium by a fibrous tissue layer called the tunica albuginea.
- The differentiation of male and female gonads is indistinguishable at the level of the genital ridges.
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