10 Questions
Which enzyme is responsible for converting angiotensinogen into angiotensin I?
Renin
Which enzyme is involved in the maintenance of interprandial glucose homeostasis?
Both Glucose 6-phosphatase-α and Glucose 6-phosphatase-β
Which enzyme is involved in glycogen storage disease type I (von Gierke's disease) resulting in hepatomegaly and renomegaly?
Glucose 6-phosphatase
Which enzyme is involved in the inhibition of the reabsorption of NaCl through the activation of bradykinin-B2 receptors?
Kallikrein
Which enzyme is part of the renin-angiotensin-aldosterone system and regulates blood pressure by controlling the production of aldosterone?
Renin
What is the function of the renal kallikrein-kinin system in the nephrons of the kidney?
To inhibit the reabsorption of ions
Which enzyme is involved in the synthesis of the active form of vitamin D?
1α-Hydroxylase
What is the clinical significance of 11β-hydroxysteroid dehydrogenase type 2 deficiency?
Apparent mineralocorticoid excess (AME)
Where is 11β-hydroxysteroid dehydrogenase type 1 highly expressed?
Liver, adipose tissue, and the central nervous system
What is the function of Tissue Kallikrein in the kidney?
To prevent and reverse kidney injury, inflammation, and fibrosis
Test your knowledge about the location, function, and clinical significance of Renin and Glucose-6-Phosphatase in the body. Learn about their roles in regulating blood pressure, Na/K levels, and their importance as diagnostic tools for kidney and heart failure, as well as diabetes.
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