Renal Physiology Overview

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Questions and Answers

What is the primary function of the urinary system?

  • Filtering and excreting waste products (correct)
  • Producing hormones
  • Regulating blood pressure
  • Maintaining body temperature

Which structure in the nephron is responsible for the filtration of blood?

  • Glomerulus (correct)
  • Loop of Henle
  • Collecting duct
  • Proximal convoluted tubule

How does the nephron contribute to maintaining homeostasis of water balance?

  • By producing excess hormones
  • By filtering out all blood components
  • By increasing urine production during dehydration
  • By reabsorbing water and electrolytes as needed (correct)

What is the correct pathway of blood flow through the nephron?

<p>Afferent arteriole → Glomerulus → Efferent arteriole → Proximal convoluted tubule (D)</p> Signup and view all the answers

Which of the following best describes the term 'homeostasis' in relation to the urinary system?

<p>The process of maintaining a stable internal environment (A)</p> Signup and view all the answers

What is the primary location for filtration in the nephron?

<p>Glomerulus and glomerular capsule (B)</p> Signup and view all the answers

Which process involves the movement of substances from the blood back into the nephron?

<p>Selective reabsorption (D)</p> Signup and view all the answers

What hormone is responsible for increasing the reabsorption of sodium?

<p>Aldosterone (A)</p> Signup and view all the answers

What happens if all carrier sites for reabsorption are full?

<p>Excess substances are removed in urine (C)</p> Signup and view all the answers

Which of the following functions is NOT performed by the kidney?

<p>Blood oxygenation (B)</p> Signup and view all the answers

In which section of the nephron does the selective reabsorption mostly occur?

<p>Proximal convoluted tubule (D)</p> Signup and view all the answers

Which component typically does NOT pass through the semipermeable walls during filtration?

<p>Blood cells (C)</p> Signup and view all the answers

What is the main function of the renal threshold in the reabsorption process?

<p>To determine maximum reabsorption capacity (B)</p> Signup and view all the answers

What role does angiotensin II play in the body?

<p>It acts as a vasoconstricting hormone. (A)</p> Signup and view all the answers

What substances are actively secreted into the convoluted tubules during tubular secretion?

<p>Hydrogen ions and drugs like penicillin. (B)</p> Signup and view all the answers

How does the body primarily lose water?

<p>In urine, faeces, perspiration, and expired air. (D)</p> Signup and view all the answers

Which hormone is responsible for regulating sodium excretion?

<p>Aldosterone. (C)</p> Signup and view all the answers

What effect does parathyroid hormone (PTH) have on calcium balance?

<p>It enhances calcium reabsorption by kidney tubules. (B)</p> Signup and view all the answers

Which of the following accurately describes water regulation?

<p>Water balance is maintained through renal function and hormone regulation. (B)</p> Signup and view all the answers

What is the primary process by which substances are filtered from the blood in the kidneys?

<p>Ultrafiltration in the glomerulus. (A)</p> Signup and view all the answers

What is a function of calcitonin regarding calcium levels in the body?

<p>It decreases calcium reabsorption by the kidneys. (B)</p> Signup and view all the answers

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Study Notes

Angiotensin II

  • Vasoconstricting hormone

Tubular Secretion

  • Some substances remain in the blood after filtration due to speed of filtration
  • These include: hydrogen ions, drugs like penicillin and aspirin
  • These substances are actively secreted into the convoluted tubules
  • Energy is required for this process

Glomerular Filtrates

  • Water, glucose, amino acids, urea and salts are present in the glomerular filtrates

Composition Of Urine

  • Urea, creatinine, uric acid, water and salts

Water Balance

  • The body gains water from food and drink
  • The body loses water through urine, faeces, sweat, and expired air

Water Regulation By Antidiuretic Hormone

  • Antidiuretic hormone (ADH) increases water reabsorption by increasing the permeability of the convoluted tubules

Electrolyte Balance

  • Sodium and Potassium are ingested in food
  • Excess is excreted in urine
  • Aldosterone regulates sodium excretion
  • Calcium balance - regulated by parathyroid hormone (PTH) and calcitonin
  • PTH acts on kidney tubules to reabsorb calcium
  • Calcitonin acts on kidney tubules to absorb less calcium

Renal Function

  • Maintains normal body fluid volume and composition
  • Essential for the excretion of waste products and drugs

Functions Of The Kidney

  • Excretory
  • Regulatory
  • Endocrine
  • Metabolic

Formation Of Urine

  • Filtration
  • Selective reabsorption
  • Tubular secretion

Glomerular Capsule

  • Where filtration takes place

Filtration

  • Water and small molecules pass through the semipermeable walls of the glomerulus and glomerular capsule
  • Larger molecules, blood cells, and plasma proteins remain in the capillaries

Selective Reabsorption

  • Takes place in the tubules
  • Constituents needed by the body are reabsorbed back into the blood capillary
  • Active transport occurs at carrier sites in the epithelial membrane
  • Energy is required to transport substances against their concentration gradients
  • Renal threshold – if all carrier sites are full, substances will appear in urine

Reabsorption Regulated By Hormones

  • Parathormone and calcitonin regulate calcium and phosphate reabsorption
  • Antidiuretic hormone increases water reabsorption
  • Aldosterone increases sodium reabsorption and potassium excretion

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