Podcast
Questions and Answers
Water leaves the lumen (water ______)
Water leaves the lumen (water ______)
permeable
Osmolality increases as its higher within the medulla than in ______
Osmolality increases as its higher within the medulla than in ______
tubule
NaCl leaves passively down conc gradient (higher conc in lumen than ______) and urea enters
NaCl leaves passively down conc gradient (higher conc in lumen than ______) and urea enters
medulla
Principal cells (75% in cortical, >90% in medullary and 100% in ______) o Under light microscopy, they are light in appearance o Responsible for reabsorbing Na and increasing K secretion
Principal cells (75% in cortical, >90% in medullary and 100% in ______) o Under light microscopy, they are light in appearance o Responsible for reabsorbing Na and increasing K secretion
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Changes in afferent/efferent arteriolar tone changes RBF Arteriolar tone – how ______ the vessel is
Changes in afferent/efferent arteriolar tone changes RBF Arteriolar tone – how ______ the vessel is
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Flow (Q) = P/R (hydrostatic pressure between artery and vein / vascular resistance) - If perfusion pressure is constant: o Constriction of afferent / efferent arteriole in RBF o Dilation of afferent / efferent arteriole in RBF - Factors that influence RBF: angiotensin II, adrenaline, noradrenaline, ADH Renin angiotensin system Angiotensinogen (gamma globulin)
Flow (Q) = P/R (hydrostatic pressure between artery and vein / vascular resistance) - If perfusion pressure is constant: o Constriction of afferent / efferent arteriole in RBF o Dilation of afferent / efferent arteriole in RBF - Factors that influence RBF: angiotensin II, adrenaline, noradrenaline, ADH Renin angiotensin system Angiotensinogen (gamma globulin)
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Angiotensinogen (gamma globulin) is produced in ______
Angiotensinogen (gamma globulin) is produced in ______
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Renin is ______ enzyme produced by the kidney
Renin is ______ enzyme produced by the kidney
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Regulation of water balance is primarily controlled by the ______ in the hypothalamus
Regulation of water balance is primarily controlled by the ______ in the hypothalamus
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The release of ADH into the blood is stimulated by ______ situations
The release of ADH into the blood is stimulated by ______ situations
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ADH interacts with the V2 receptor on the ______ membrane of the principal cells of the collecting duct
ADH interacts with the V2 receptor on the ______ membrane of the principal cells of the collecting duct
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Aldosterone acts on the principal cells of the collecting duct and distal convoluted tubule to increase ______ reabsorption
Aldosterone acts on the principal cells of the collecting duct and distal convoluted tubule to increase ______ reabsorption
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Proximal tubule solutes PAH Used to measure effective renal plasma flow
Proximal tubule solutes PAH Used to measure effective renal plasma flow
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In S1: lumen is –ve (reabsorbing Na, which is +ve along with neutral solute)
In S1: lumen is –ve (reabsorbing Na, which is +ve along with neutral solute)
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Principal cells (75% in cortical, >90% in medullary and 100% in ______) o Under light microscopy, they are light in appearance o Responsible for reabsorbing Na and increasing K secretion
Principal cells (75% in cortical, >90% in medullary and 100% in ______) o Under light microscopy, they are light in appearance o Responsible for reabsorbing Na and increasing K secretion
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Regulation of water balance is primarily controlled by the ______ in the hypothalamus
Regulation of water balance is primarily controlled by the ______ in the hypothalamus
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