Renal Infarcts Progression

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Questions and Answers

What histologic changes are typically observed in renal infarcts?

  • Ischemic coagulative necrosis (correct)
  • Fibrous scarring
  • Granulomatous inflammation
  • Purulent exudate formation

What is a common clinical manifestation of large renal infarcts?

  • Unilateral flank pain
  • Polyuria
  • Bilateral flank pain
  • Hematuria (correct)

What is the most common renal abnormality associated with sickle cell nephropathy?

  • Proteinuria
  • Dysuria
  • Hematuria (correct)
  • Glomerulonephritis

What may lead to hypertension in cases of large kidney infarcts?

<p>Narrowing of the renal artery (B)</p> Signup and view all the answers

What is responsible for the increased intracellular sickle hemoglobin concentrations in sickle cell nephropathy?

<p>Hyperosmolarity dehydrating red cells (D)</p> Signup and view all the answers

What is a possible consequence of patchy papillary necrosis seen in sickle cell nephropathy?

<p>Cortical scarring (C)</p> Signup and view all the answers

Which type of renal dysplasia or hypoplasia accounts for 20% of chronic kidney disease in children?

<p>Renal dysplasia caused by acquired defects during gestation (A)</p> Signup and view all the answers

Which genetic defect primarily produces functional abnormalities in tubular transport?

<p>Cystinuria genes (B)</p> Signup and view all the answers

Which congenital renal anomaly is usually incompatible with life in affected infants?

<p>Bilateral agenesis (A)</p> Signup and view all the answers

What is the most likely origin of clear cell carcinomas in the kidney?

<p>Proximal tubular epithelium (B)</p> Signup and view all the answers

What complication can develop in the remaining kidney of patients with unilateral kidney agenesis?

<p>Progressive glomerular sclerosis (C)</p> Signup and view all the answers

What is the characteristic color of clear cell carcinomas in the kidney?

<p>Yellow (C)</p> Signup and view all the answers

What structural components are primarily involved in the developmental abnormalities associated with congenital renal disease?

<p>Both kidney and urinary tract (A)</p> Signup and view all the answers

What feature is commonly observed in clear cell carcinomas in the kidney?

<p>Sharp defined margins extending beyond the renal capsule (C)</p> Signup and view all the answers

In cases of renal dysplasias or hypoplasias, which condition can ensue as a result of adaptive changes in hypertrophied nephrons?

<p>Chronic kidney disease (B)</p> Signup and view all the answers

Which growth pattern can be seen in clear cell carcinomas in the kidney?

<p>Trabecular (C)</p> Signup and view all the answers

What is a common histological feature of clear cell carcinomas in the kidney?

<p>Rounded or polygonal tumor cells with clear cytoplasm (D)</p> Signup and view all the answers

What is a common feature seen in clear cell carcinomas as they enlarge?

<p>Bulging into the renal calyces and pelvis (D)</p> Signup and view all the answers

What is a key feature that distinguishes renal cysts from renal tumors in radiologic studies?

<p>Smooth contours (B)</p> Signup and view all the answers

Which complex is implicated in the pathogenesis of major cystic kidney diseases, including polycystic kidney disease?

<p>Cilium-centrosome complex (D)</p> Signup and view all the answers

What cellular dysfunction leads to renal cyst formation?

<p>Abnormal primary cilium function (A)</p> Signup and view all the answers

What is a common histological feature of acquired renal cystic disease in patients with ESRD?

<p>Lack of calcium oxalate crystals (B)</p> Signup and view all the answers

In patients with ESRD who have undergone prolonged dialysis, what size range do the renal cysts typically measure?

<p>0.1-4 cm in diameter (B)</p> Signup and view all the answers

What type of epithelium may line the renal cysts observed in acquired cystic disease?

<p>Flattened tubular epithelium (B)</p> Signup and view all the answers

Which of the following best describes renal hypoplasia?

<p>Developmental failure resulting in small kidneys with no scars (C)</p> Signup and view all the answers

What distinguishes true renal hypoplasia from acquired atrophic kidneys?

<p>Reduced number of lobes and pyramids (A)</p> Signup and view all the answers

Where can ectopic kidneys be found?

<p>Just above the pelvic brim or within the pelvis (A)</p> Signup and view all the answers

What is the prevalence of horseshoe kidneys in autopsies?

<p>1 in 500 to 1000 autopsies (C)</p> Signup and view all the answers

What is a common consequence of abnormal position of cystic kidneys?

<p>Obstruction to urinary flow causing bacterial infections (A)</p> Signup and view all the answers

Cystic diseases of the kidney are heterogeneous and include which types of disorders?

<p>Hereditary, developmental, and acquired disorders (C)</p> Signup and view all the answers

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