Renal Health: Hypocalcemia and Osteodystrophy

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Questions and Answers

What is the purpose of constructing a meaningful stem in a question?

  • To provide a definite problem without irrelevant material (correct)
  • To make the question longer
  • To distract students from the answer
  • To include as many options as possible

Why should distractors in a multiple-choice question be plausible?

  • To represent common misconceptions and challenge student understanding (correct)
  • To ensure that students can guess the answer correctly
  • To confuse students completely
  • To enhance the difficulty of finding the correct answer

What should be avoided when formulating answer options?

  • Using varied phrasing for each option
  • Including clear and concise statements
  • Referencing similar content form through distractors
  • Using phrases like 'all of the above' or 'none of the above' (correct)

What is a key characteristic of the correct answer to a multiple-choice question?

<p>It must be referenced in the content (C)</p> Signup and view all the answers

What is the advantage of using a consistent case in questions?

<p>It helps in maintaining clarity and uniformity (A)</p> Signup and view all the answers

What condition is associated with low calcium levels due to decreased 1-alpha-hydroxylation of vitamin D?

<p>Hypocalcemia (D)</p> Signup and view all the answers

Which mineral imbalance is a consequence of renal failure and can lead to hypocalcemia?

<p>Hyperphosphatemia (A)</p> Signup and view all the answers

What is a potential complication that can arise in shrunken end-stage kidneys during dialysis?

<p>Renal cell carcinoma (B)</p> Signup and view all the answers

Which of the following describes a bone condition stemming from secondary hyperparathyroidism associated with renal failure?

<p>Osteomalacia (B)</p> Signup and view all the answers

What are the main treatment options for renal failure?

<p>Dialysis or renal transplant (C)</p> Signup and view all the answers

What is the primary cause of urinary tract infections in females?

<p>Ascending infection (A)</p> Signup and view all the answers

Which of the following symptoms is typical in cystitis?

<p>Suprapubic pain (D)</p> Signup and view all the answers

What is considered the gold standard for diagnosing a urinary tract infection?

<p>Culture with greater than 100,000 colony forming units (A)</p> Signup and view all the answers

Which organism is the most common cause of urinary tract infections?

<p>E. coli (A)</p> Signup and view all the answers

Which factor is not typically considered a risk factor for urinary tract infections?

<p>Use of antibiotics (D)</p> Signup and view all the answers

What does sterile pyuria indicate in a patient?

<p>Urethritis likely caused by <em>Chlamydia trachomatis</em> or <em>Neisseria gonorrhoeae</em> (C)</p> Signup and view all the answers

What is a common cause of chronic pyelonephritis in children?

<p>Vesicoureteral reflux (D)</p> Signup and view all the answers

Which of the following symptoms is indicative of pyelonephritis?

<p>Unilateral flank pain and WBC casts (A)</p> Signup and view all the answers

Which pathogen is most commonly associated with pyelonephritis?

<p><em>E. coli</em> (D)</p> Signup and view all the answers

What is the primary symptom of nephrolithiasis?

<p>Colicky pain with hematuria (B)</p> Signup and view all the answers

What can result from chronic renal failure?

<p>Uremia and azotemia leading to systemic complications (C)</p> Signup and view all the answers

Which condition is characterized by interstitial fibrosis due to repeated infections?

<p>Chronic pyelonephritis (C)</p> Signup and view all the answers

In chronic renal failure, which of the following is a common metabolic disturbance?

<p>Hyperkalemia with metabolic acidosis (B)</p> Signup and view all the answers

Flashcards

Hypocalcemia in Renal Failure

Low blood calcium levels caused by the kidney's inability to activate vitamin D, and high phosphate levels.

Renal Osteodystrophy

Bone disease in kidney failure due to overactive parathyroid glands, weak bones, and porous bones.

Dialysis

Treatment that uses a machine to filter the blood when the kidneys fail.

Renal Transplant

The surgical procedure to replace a failing kidney.

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Cysts in Dialysis Patients

Fluid-filled sacs that grow in damaged kidneys during dialysis, increasing risk of kidney cancer.

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Urinary Tract Infection (UTI)

Infection of the urethra, bladder, or kidney. Most often caused by bacteria traveling upwards from the urethra.

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Cystitis

Infection of the bladder. Symptoms include painful urination, frequent urination, a strong urge to urinate, and pain in the lower abdomen. Fever is usually absent.

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E. coli

A common bacteria that causes UTI's, especially in women, and is the culprit in 80% of cases.

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Urine Culture

The amount of bacteria in a urine sample. A count greater than 100,000 colony forming units confirms a UTI.

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String

A sequence of characters, like letters, numbers, and symbols, used to represent text or code. Think of it like a chain of beads, where each bead is a character.

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Boolean

A specific type of data that represents true or false values. Often used to represent conditions, like whether something is on or off.

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Null

A value that holds no information. Think of an empty box or a blank space.

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Array

A collection of data points, each with its own unique identifier. Think of a list of people, where each person has a name and address.

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Object

A structure used to organize data in a key-value pair. Think of it like a dictionary with words and their meanings, or a list of names and their phone numbers.

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Pyelonephritis

A type of bacterial infection that affects the kidney, usually caused by an ascending infection from the bladder. It can be more common in individuals with vesicoureteral reflux.

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Chronic Pyelonephritis

A condition marked by interstitial fibrosis and atrophy of the kidney tubules due to repeated episodes of acute pyelonephritis. It can result from conditions like vesicoureteral reflux in children or obstruction in adults.

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Pyuria

The presence of white blood cells in the urine, often indicating an infection or inflammation in the urinary tract.

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Nephrolithiasis (Kidney Stones)

A kidney stone is formed when a urinary solute precipitates out of solution and forms a solid mass. Factors like high solute concentration in the urine and low urine volume increase the risk.

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Chronic Renal Failure

The final stage of kidney failure, where the kidneys are unable to filter waste products from the blood effectively. Common causes include diabetes, hypertension, and glomerular diseases.

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Uremia

A condition where the kidneys lose their ability to filter waste products from the blood, leading to an accumulation of waste products in the blood, salt and water retention, electrolyte imbalances, and other complications.

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Enterococcus faecalis

A type of bacteria that also contributes to urinary tract infections, including pyelonephritis.

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Study Notes

Hypocalcemia

  • Hypocalcemia results from decreased 1-alpha-hydroxylation of vitamin D by proximal renal tubule cells and hyperphosphatemia.

Renal Osteodystrophy

  • Renal osteodystrophy is due to secondary hyperparathyroidism, osteomalacia, and osteoporosis.

Treatment

  • Treatment involves dialysis or renal transplant.
  • Cysts often develop in shrunken end-stage kidneys during dialysis, increasing the risk for renal cell carcinoma.

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