Renal Function and Chronic Kidney Disease
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Questions and Answers

What is a primary role of renal function in the body?

  • Regulating metabolism of carbohydrates
  • Facilitating digestion of proteins
  • Maintaining normal body fluid volume and composition (correct)
  • Producing hormones for growth
  • Which of the following is NOT a cause of loss of renal function?

  • Asthma (correct)
  • Diabetes
  • Hypertension
  • Renal tract infections
  • Which symptom is commonly associated with kidney disease?

  • Severe headaches
  • Unexplained weight gain
  • Increased appetite
  • Frequent urination (correct)
  • What is a general management strategy for patients with kidney disease?

    <p>Strict adherence to a balanced diet and fluid intake</p> Signup and view all the answers

    Which of the following is a dental relevance of renal disease?

    <p>Elevated risk for oral infections</p> Signup and view all the answers

    What is a common initial symptom of chronic kidney disease?

    <p>Increased thirst</p> Signup and view all the answers

    Which of the following gastrointestinal effects can result from chronic kidney disease?

    <p>Hiccups</p> Signup and view all the answers

    What effect does chronic kidney disease have on hematological health?

    <p>Anaemia due to erythropoietin deficiency</p> Signup and view all the answers

    Which of the following best describes a potential cardiovascular effect of chronic kidney disease?

    <p>Hypertension</p> Signup and view all the answers

    Which of the following options is NOT a potential effect of chronic kidney disease?

    <p>Flu-like symptoms</p> Signup and view all the answers

    Which of the following is a sign of kidney disease associated with water retention?

    <p>Swollen ankles</p> Signup and view all the answers

    What percentage of patients on haemodialysis survive at least 5 years?

    <p>70%</p> Signup and view all the answers

    What is a commonly prescribed medication approach for patients after a renal transplantation?

    <p>Immunosuppressants</p> Signup and view all the answers

    Which of the following signs is NOT typically associated with kidney disease?

    <p>Increased thirst</p> Signup and view all the answers

    Patients who have undergone renal transplantation are susceptible to which type of health issue?

    <p>Infection</p> Signup and view all the answers

    Study Notes

    Renal Function

    • Renal function is essential for maintaining normal body fluid volume and composition, excretion of waste products and drugs.

    Causes of Loss of Renal Function

    • Renal Disease:
      • Glomerulonephritis
      • Hypertension
      • Diabetes
      • Congenital abnormalities
      • Renal tract infections
    • Renal Hypofunction
      • Severe shock or hemorrhage
    • Blockage of Renal Outflow
      • Kidney stones
      • Prostate tumours

    Effects on the Body

    • Chronic Kidney Disease (CKD) (aka chronic renal failure):
      • Progressive and irreversible kidney damage, impacting most body systems
      • Results in decreased function of all kidney functions
      • No symptoms initially

    Potential Impact of Chronic Kidney Disease (CKD)

    Metabolic Effects

    • Thirst
    • Urination at night
    • Glucose in urine
    • Electrolyte disturbances

    Cardiovascular Effects

    • Hypertension
    • Atheroma

    Gastrointestinal Effects

    • Loss of appetite
    • Weight loss
    • Nausea and vomiting
    • Peptic ulcer
    • Hiccups

    Neuromuscular Effects

    • Headaches
    • Drowsiness
    • Tremors

    Haematological Effects

    • Bleeding due to platelet dysfunction and/or anticoagulant medication
    • Anemia due to deficiency of erythropoietin

    Other Effects

    • Bruises
    • Rashes
    • Increased proneness to infection

    Signs & Symptoms of Kidney Disease

    • Weight loss and poor appetite
    • Swollen ankles, feet or hands
    • Shortness of breath (dyspnoea)
    • Increased need to urinate (especially at night)
    • Insomnia
    • Itchy skin
    • Blood in urine (haematuria)

    General Management

    • Dialysis can give normal life to up to 20% of patients but cannot prevent all complications.
    • Over 70% of patients on haemodialysis survive at least 5 years.
    • Renal transplant may become necessary.

    Kidney Dialysis

    • A treatment option for kidney failure.

    Renal transplantations

    • Common treatment option with 90% graft survival at one year.
    • Patients require immunosuppression after transplant.

    Post Transplantation

    • Patients may still experience problems associated with renal failure.
    • Vulnerable to infection due to immunosuppression.

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    Description

    Explore the essential functions of the kidneys, including their role in fluid balance and waste excretion. Understand the causes and impacts of renal function loss, with a focus on chronic kidney disease (CKD) and its metabolic, cardiovascular, and gastrointestinal effects. Test your knowledge on this critical topic in human health.

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