Renal Function and Chronic Kidney Disease

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Questions and Answers

What is a primary role of renal function in the body?

  • Regulating metabolism of carbohydrates
  • Facilitating digestion of proteins
  • Maintaining normal body fluid volume and composition (correct)
  • Producing hormones for growth

Which of the following is NOT a cause of loss of renal function?

  • Asthma (correct)
  • Diabetes
  • Hypertension
  • Renal tract infections

Which symptom is commonly associated with kidney disease?

  • Severe headaches
  • Unexplained weight gain
  • Increased appetite
  • Frequent urination (correct)

What is a general management strategy for patients with kidney disease?

<p>Strict adherence to a balanced diet and fluid intake (A)</p> Signup and view all the answers

Which of the following is a dental relevance of renal disease?

<p>Elevated risk for oral infections (C)</p> Signup and view all the answers

What is a common initial symptom of chronic kidney disease?

<p>Increased thirst (A)</p> Signup and view all the answers

Which of the following gastrointestinal effects can result from chronic kidney disease?

<p>Hiccups (A)</p> Signup and view all the answers

What effect does chronic kidney disease have on hematological health?

<p>Anaemia due to erythropoietin deficiency (A)</p> Signup and view all the answers

Which of the following best describes a potential cardiovascular effect of chronic kidney disease?

<p>Hypertension (D)</p> Signup and view all the answers

Which of the following options is NOT a potential effect of chronic kidney disease?

<p>Flu-like symptoms (C)</p> Signup and view all the answers

Which of the following is a sign of kidney disease associated with water retention?

<p>Swollen ankles (C)</p> Signup and view all the answers

What percentage of patients on haemodialysis survive at least 5 years?

<p>70% (C)</p> Signup and view all the answers

What is a commonly prescribed medication approach for patients after a renal transplantation?

<p>Immunosuppressants (A)</p> Signup and view all the answers

Which of the following signs is NOT typically associated with kidney disease?

<p>Increased thirst (B)</p> Signup and view all the answers

Patients who have undergone renal transplantation are susceptible to which type of health issue?

<p>Infection (C)</p> Signup and view all the answers

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Study Notes

Renal Function

  • Renal function is essential for maintaining normal body fluid volume and composition, excretion of waste products and drugs.

Causes of Loss of Renal Function

  • Renal Disease:
    • Glomerulonephritis
    • Hypertension
    • Diabetes
    • Congenital abnormalities
    • Renal tract infections
  • Renal Hypofunction
    • Severe shock or hemorrhage
  • Blockage of Renal Outflow
    • Kidney stones
    • Prostate tumours

Effects on the Body

  • Chronic Kidney Disease (CKD) (aka chronic renal failure):
    • Progressive and irreversible kidney damage, impacting most body systems
    • Results in decreased function of all kidney functions
    • No symptoms initially

Potential Impact of Chronic Kidney Disease (CKD)

Metabolic Effects

  • Thirst
  • Urination at night
  • Glucose in urine
  • Electrolyte disturbances

Cardiovascular Effects

  • Hypertension
  • Atheroma

Gastrointestinal Effects

  • Loss of appetite
  • Weight loss
  • Nausea and vomiting
  • Peptic ulcer
  • Hiccups

Neuromuscular Effects

  • Headaches
  • Drowsiness
  • Tremors

Haematological Effects

  • Bleeding due to platelet dysfunction and/or anticoagulant medication
  • Anemia due to deficiency of erythropoietin

Other Effects

  • Bruises
  • Rashes
  • Increased proneness to infection

Signs & Symptoms of Kidney Disease

  • Weight loss and poor appetite
  • Swollen ankles, feet or hands
  • Shortness of breath (dyspnoea)
  • Increased need to urinate (especially at night)
  • Insomnia
  • Itchy skin
  • Blood in urine (haematuria)

General Management

  • Dialysis can give normal life to up to 20% of patients but cannot prevent all complications.
  • Over 70% of patients on haemodialysis survive at least 5 years.
  • Renal transplant may become necessary.

Kidney Dialysis

  • A treatment option for kidney failure.

Renal transplantations

  • Common treatment option with 90% graft survival at one year.
  • Patients require immunosuppression after transplant.

Post Transplantation

  • Patients may still experience problems associated with renal failure.
  • Vulnerable to infection due to immunosuppression.

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