Relaxin and Prostaglandins in Pregnancy

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Questions and Answers

What are the main hormones involved in the initiation and maintenance of parturition?

  • Glucagon and aldosterone
  • Sex steroids, oxytocin, prostaglandins, and relaxin (correct)
  • Insulin and cortisol
  • Leptin and growth hormone

What is the primary effect of oxytocin during parturition?

  • Promotion of uterine quiescence
  • Prevention of cervical dilation
  • Induction of myometrial contraction (correct)
  • Inhibition of prostaglandin synthesis

During which phase of parturition does the myometrium transform from a quiescent state to a highly contractile state?

  • Quiescence Phase 0
  • Transformation/Activation Phase 1 (correct)
  • Involution Phase 3
  • Active Labor Phase 2

What happens immediately after the expulsion of uterine content during parturition?

<p>Uterine homeostasis is facilitated by myometrial contractions (A)</p> Signup and view all the answers

Which hormones are primarily responsible for mammary gland development during pregnancy and lactation?

<p>Estrogen and progesterone (D)</p> Signup and view all the answers

What is the role of prolactin in lactation?

<p>Promoting mammary gland development (C)</p> Signup and view all the answers

What is the primary stimulus for the release of oxytocin during labor?

<p>Distention of the cervix (Ferguson Reflex) (A)</p> Signup and view all the answers

What role does progesterone play in the initiation of human labor?

<p>Lowers excitability of myometrial cells (A)</p> Signup and view all the answers

What is the function of estrogen in labor?

<p>Increases myometrial contractility (A)</p> Signup and view all the answers

Which hormone is synthesized in the hypothalamus and plays a crucial role in stimulating uterine smooth muscle contractions?

<p>Oxytocin (C)</p> Signup and view all the answers

What is the effect of oxytocin on uterine smooth muscle contraction?

<p>Increases contractility (D)</p> Signup and view all the answers

When does oxytocin levels peak significantly during labor?

<p>In early labor (D)</p> Signup and view all the answers

What is the primary action of Relaxin during pregnancy?

<p>Maintain the uterus in a quiet state (A)</p> Signup and view all the answers

Which hormone is responsible for the initiation of milk secretion after childbirth?

<p>Prolactin (A)</p> Signup and view all the answers

What stimulates the release of oxytocin for the 'Milk Let Down' process?

<p>Sucking and nipple stimulation (B)</p> Signup and view all the answers

Which hormone plays a crucial role in promoting mammary growth?

<p>Estrogens (A)</p> Signup and view all the answers

In lactation, what is the main function of oxytocin?

<p>Uterine contractions (C)</p> Signup and view all the answers

What is the main action of prolactin in the context of lactation?

<p>Promotion of mammary growth (A)</p> Signup and view all the answers

Which hormone is essential for milk production and maintenance?

<p>Prolactin (D)</p> Signup and view all the answers

What is the physiological role of Prostaglandins in lactation?

<p>Enhance milk ejection (D)</p> Signup and view all the answers

What is the main effect of oxytocin on myoepithelial cells during lactation?

<p>Contraction of myoepithelial cells surrounding alveoli (A)</p> Signup and view all the answers

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