Relaxin and Prostaglandins in Pregnancy

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21 Questions

What are the main hormones involved in the initiation and maintenance of parturition?

Sex steroids, oxytocin, prostaglandins, and relaxin

What is the primary effect of oxytocin during parturition?

Induction of myometrial contraction

During which phase of parturition does the myometrium transform from a quiescent state to a highly contractile state?

Transformation/Activation Phase 1

What happens immediately after the expulsion of uterine content during parturition?

Uterine homeostasis is facilitated by myometrial contractions

Which hormones are primarily responsible for mammary gland development during pregnancy and lactation?

Estrogen and progesterone

What is the role of prolactin in lactation?

Promoting mammary gland development

What is the primary stimulus for the release of oxytocin during labor?

Distention of the cervix (Ferguson Reflex)

What role does progesterone play in the initiation of human labor?

Lowers excitability of myometrial cells

What is the function of estrogen in labor?

Increases myometrial contractility

Which hormone is synthesized in the hypothalamus and plays a crucial role in stimulating uterine smooth muscle contractions?

Oxytocin

What is the effect of oxytocin on uterine smooth muscle contraction?

Increases contractility

When does oxytocin levels peak significantly during labor?

In early labor

What is the primary action of Relaxin during pregnancy?

Maintain the uterus in a quiet state

Which hormone is responsible for the initiation of milk secretion after childbirth?

Prolactin

What stimulates the release of oxytocin for the 'Milk Let Down' process?

Sucking and nipple stimulation

Which hormone plays a crucial role in promoting mammary growth?

Estrogens

In lactation, what is the main function of oxytocin?

Uterine contractions

What is the main action of prolactin in the context of lactation?

Promotion of mammary growth

Which hormone is essential for milk production and maintenance?

Prolactin

What is the physiological role of Prostaglandins in lactation?

Enhance milk ejection

What is the main effect of oxytocin on myoepithelial cells during lactation?

Contraction of myoepithelial cells surrounding alveoli

This quiz covers the production and roles of relaxin and prostaglandins in pregnancy. It discusses how relaxin helps maintain the uterus during pregnancy and softens the cervix, while prostaglandins play a role in initiating labor by stimulating uterine smooth muscle contractions.

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