Regulation of Gene Expression - Unit 2

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What is the role of small RNA's in gene expression?

Small RNA's play a role in gene expression by inhibiting expression of genes.

What is the function of Dicer in post transcriptional control?

Dicer cuts double stranded RNA into smaller RNA's called microRNA (miRNA) and small interfering RNA (siRNA's).

How do miRNA's affect gene expression?

miRNA's bind to mRNA and prevent translation.

What is the role of siRNA's in gene expression regulation?

siRNA's break apart mRNA before it's translated.

How do siRNA's contribute to heterochromatin formation?

siRNA's play a role in heterochromatin formation by blocking large regions of the chromosome.

What is the function of small RNAs in chromatin modification?

Small RNAs can promote the formation of heterochromatin in certain regions, blocking transcription.

Describe the process of RNA interference in post-transcriptional control.

RNA interference involves RNA forming double stranded loops from newly formed mRNA, with loops inhibiting gene expression.

Explain how small RNAs regulate gene expression at the post-transcriptional level.

Small RNAs regulate gene expression post-transcriptionally by binding to mRNA and preventing translation.

What is the significance of post-transcriptional control in gene regulation?

Post-transcriptional control mechanisms, like miRNA and siRNA, fine-tune gene expression beyond transcription.

How do miRNA's and siRNA's differ in their mechanisms of action?

miRNA's bind to mRNA and prevent translation, while siRNA's break apart mRNA before translation.

Test your knowledge on the regulation of gene expression in Unit 2, covering topics such as flow of genetic information, genes to proteins, chromosome structure, and more. Get ready to understand the connection between genotype and phenotype.

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