12 Questions
What is the primary role of malonyl CoA in regulating fatty acid metabolism?
To inhibit carnitine acyl transferase I and promote triglyceride synthesis
What is the effect of insulin on fatty acid breakdown?
It inhibits fatty acid breakdown
What is the primary source of energy for the brain during starvation?
Ketone bodies
What is the role of AMP-activated protein kinase in regulating fatty acid metabolism?
It reduces fatty acid synthesis and enhances fatty acid β oxidation
What is the effect of glucagon on fatty acid metabolism?
It promotes fatty acid breakdown
What is the primary fate of fatty acid CoA when there is plenty of glucose available?
It is converted to triacylglycerol in the liver
What is the primary condition that leads to the formation of ketone bodies?
Imbalance of fat and carbohydrate degradation
Explain how the availability of fatty acids affects their oxidation.
The availability of fatty acids affects their oxidation, as when there is plenty of fatty acids available, they will be broken down, but when there isn't many available, they won't be broken down.
Describe the role of glucagon and adrenaline in fatty acid metabolism.
Glucagon and adrenaline promote fatty acid breakdown.
How does the formation of malonyl CoA affect fatty acid metabolism?
The formation of malonyl CoA inhibits carnitine acyl transferase I, resulting in triglyceride synthesis and turning off fatty acid degradation.
Explain how changes in AMP levels affect fatty acid metabolism.
When there is high AMP, the AMP-activated protein kinase is activated, reducing fatty acid synthesis and enhancing fatty acid β oxidation.
What is the significance of ketone bodies in regulating fatty acid metabolism?
Ketone bodies are formed when there is an imbalance of fat and carbohydrate degradation, and they serve as an alternative source of energy for the brain.
Learn about the regulation of fatty acid oxidation, including the role of substrate availability, hormonal regulation, and fatty acid CoA in the breakdown of fatty acids. Understand how insulin, glucagon, and adrenaline affect fatty acid metabolism.
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