Regulation of Fatty Acid Oxidation

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Questions and Answers

What is the primary role of malonyl CoA in regulating fatty acid metabolism?

To activate AMP-activated protein kinase
To promote ketone body formation
To inhibit carnitine acyl transferase I and promote triglyceride synthesis (correct)
To stimulate fatty acid β oxidation

What is the effect of insulin on fatty acid breakdown?

It inhibits fatty acid breakdown (correct)
It has no effect on fatty acid breakdown
It promotes fatty acid breakdown
It stimulates ketone body formation

What is the primary source of energy for the brain during starvation?

Amino acids
Ketone bodies (correct)
Glucose
Fatty acids

What is the role of AMP-activated protein kinase in regulating fatty acid metabolism?

It reduces fatty acid synthesis and enhances fatty acid β oxidation (D) Signup and view all the answers

What is the effect of glucagon on fatty acid metabolism?

It promotes fatty acid breakdown (A) Signup and view all the answers

What is the primary fate of fatty acid CoA when there is plenty of glucose available?

It is converted to triacylglycerol in the liver (A) Signup and view all the answers

What is the primary condition that leads to the formation of ketone bodies?

Imbalance of fat and carbohydrate degradation (A) Signup and view all the answers

Explain how the availability of fatty acids affects their oxidation.

The availability of fatty acids affects their oxidation, as when there is plenty of fatty acids available, they will be broken down, but when there isn't many available, they won't be broken down. Signup and view all the answers

Describe the role of glucagon and adrenaline in fatty acid metabolism.

Glucagon and adrenaline promote fatty acid breakdown. Signup and view all the answers

How does the formation of malonyl CoA affect fatty acid metabolism?

The formation of malonyl CoA inhibits carnitine acyl transferase I, resulting in triglyceride synthesis and turning off fatty acid degradation. Signup and view all the answers

Explain how changes in AMP levels affect fatty acid metabolism.

When there is high AMP, the AMP-activated protein kinase is activated, reducing fatty acid synthesis and enhancing fatty acid β oxidation. Signup and view all the answers

What is the significance of ketone bodies in regulating fatty acid metabolism?

Ketone bodies are formed when there is an imbalance of fat and carbohydrate degradation, and they serve as an alternative source of energy for the brain. Signup and view all the answers