Regulation of Enzyme Activity

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Questions and Answers

Which model describes an enzyme having a pre-determined shape for the active site, where only substrates of specific shape can bind?

  • Sequential model
  • Lock-and-key model (correct)
  • Allosteric model
  • Induced fit model

What type of specificity involves an enzyme distinguishing between stereoisomers?

  • Substrate specificity
  • Group specificity
  • Stereochemical specificity (correct)
  • Linkage specificity

Which enzyme cleaves amino acids one at a time from the carboxyl end of a peptide chain?

  • Carboxypeptidase (correct)
  • Phosphatase
  • Oxidase
  • Isomerase

What is required for the formation of an enzyme-substrate complex?

<p>Intermediate reaction species (B)</p> Signup and view all the answers

Which type of enzyme specificity involves hydrolyzing phosphate-ester bonds in all types of phosphate esters?

<p>Linkage specificity (D)</p> Signup and view all the answers

What is the purpose of regulating enzyme activity within a cell?

<p>To prevent wasting energy (B)</p> Signup and view all the answers

In reversible noncompetitive inhibition, where does the inhibitor bind?

<p>A different site on the enzyme than the active site (B)</p> Signup and view all the answers

Why does increasing the concentration of substrate not completely overcome noncompetitive inhibition?

<p>Because the inhibitor changes the enzyme's structure (A)</p> Signup and view all the answers

Which ions are examples of noncompetitive inhibitors mentioned in the text?

<p>Lead, silver, and mercury ions (D)</p> Signup and view all the answers

What is one reason for turning off an enzyme within a cell?

<p>To prevent energy wasting (B)</p> Signup and view all the answers

Which general mechanism is associated with feedback control in enzyme regulation?

<p>Allosteric enzymes (C)</p> Signup and view all the answers

What is a zymogen?

<p>A precursor to an active enzyme (D)</p> Signup and view all the answers

Which of the following statements about allosteric enzymes is true?

<p>They have at least two binding sites (A)</p> Signup and view all the answers

What is the role of regulators in allosteric enzymes?

<p>They cause changes in the overall three-dimensional structure of the enzyme (C)</p> Signup and view all the answers

What happens when a regulator binds to an allosteric enzyme?

<p>The enzyme becomes less active (C)</p> Signup and view all the answers

What is a proteolytic enzyme?

<p>An enzyme that catalyzes the breaking down of peptide bonds (C)</p> Signup and view all the answers

What is the function of pepsinogen?

<p>It is a precursor to a digestive enzyme (B)</p> Signup and view all the answers

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