Regulation of Enzyme Activity

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Which model describes an enzyme having a pre-determined shape for the active site, where only substrates of specific shape can bind?

Lock-and-key model

What type of specificity involves an enzyme distinguishing between stereoisomers?

Stereochemical specificity

Which enzyme cleaves amino acids one at a time from the carboxyl end of a peptide chain?

Carboxypeptidase

What is required for the formation of an enzyme-substrate complex?

Intermediate reaction species

Which type of enzyme specificity involves hydrolyzing phosphate-ester bonds in all types of phosphate esters?

Linkage specificity

What is the purpose of regulating enzyme activity within a cell?

To prevent wasting energy

In reversible noncompetitive inhibition, where does the inhibitor bind?

A different site on the enzyme than the active site

Why does increasing the concentration of substrate not completely overcome noncompetitive inhibition?

Because the inhibitor changes the enzyme's structure

Which ions are examples of noncompetitive inhibitors mentioned in the text?

Lead, silver, and mercury ions

What is one reason for turning off an enzyme within a cell?

To prevent energy wasting

Which general mechanism is associated with feedback control in enzyme regulation?

Allosteric enzymes

What is a zymogen?

A precursor to an active enzyme

Which of the following statements about allosteric enzymes is true?

They have at least two binding sites

What is the role of regulators in allosteric enzymes?

They cause changes in the overall three-dimensional structure of the enzyme

What happens when a regulator binds to an allosteric enzyme?

The enzyme becomes less active

What is a proteolytic enzyme?

An enzyme that catalyzes the breaking down of peptide bonds

What is the function of pepsinogen?

It is a precursor to a digestive enzyme

Learn about the regulation of enzyme activity within cells, focusing on the process of 'turning on' and 'turning off' enzyme production. Explore examples of enzyme regulation to understand how cells efficiently manage energy and substrate concentrations.

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