Lecture 3- Reflexes, Spinal Cord & Spinal Tracts
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Questions and Answers

A lesion in the medulla oblongata disrupts the cuneate fasciculus. What sensory deficit would most likely result from this injury?

  • Impaired fine touch and proprioception on the ipsilateral side of the body. (correct)
  • Loss of motor control in the ipsilateral limbs.
  • Impaired balance and coordination.
  • Loss of pain and temperature sensation on the contralateral side of the body.

A patient exhibits an inability to maintain balance and keep their head upright. Which descending tract is most likely affected?

  • Tectospinal Tract
  • Lateral Corticospinal Tract
  • Reticulospinal Tract
  • Vestibulospinal Tract (correct)

Damage to the anterior spinocerebellar tract would most likely result in deficits related to which function?

  • Pain and temperature sensation from the trunk.
  • Unconscious proprioception from the lower limbs. (correct)
  • Motor commands to distal muscles.
  • Conscious perception of fine touch.

A patient has lost the ability to feel pain and temperature on the left side of their body. Where is the most likely location of the lesion?

<p>Right spinal cord affecting the spinothalamic tract (A)</p> Signup and view all the answers

After suffering a stroke, a patient has difficulty performing precise finger movements. Which descending tract is most likely affected?

<p>Lateral Corticospinal (D)</p> Signup and view all the answers

A person flinches and turns their head rapidly in response to a sudden loud noise. Which descending tract facilitates this response?

<p>Tectospinal (D)</p> Signup and view all the answers

Which of the following best describes the function of the reticulospinal tract?

<p>Regulation of posture and muscle tone. (C)</p> Signup and view all the answers

What would be the most likely result of damage to the anterior corticospinal tract?

<p>Impaired movement of proximal muscles on both sides of the body. (C)</p> Signup and view all the answers

If a patient has damage to the medial vestibulospinal tract, which deficit would you most likely observe?

<p>Difficulty stabilizing head position during movements. (D)</p> Signup and view all the answers

A patient reports a selective loss of vibration sense in their lower extremities. Which pathway is most likely compromised?

<p>Gracile fasciculus (B)</p> Signup and view all the answers

How does reciprocal inhibition contribute to the stretch reflex?

<p>It causes relaxation of antagonist muscles, allowing the agonist muscle to contract without opposition. (D)</p> Signup and view all the answers

During a weight-bearing flexor reflex, what is the role of the contralateral extension?

<p>To maintain balance and support the body's weight while the ipsilateral limb is withdrawn. (A)</p> Signup and view all the answers

What is the most likely explanation for the disappearance of the walking/stepping reflex around 5-6 months of age?

<p>Cortical maturation leads to inhibition of the reflex pathways, allowing for more voluntary control of movement. (C)</p> Signup and view all the answers

What is the key distinction between ascending tracts and descending tracts in the spinal cord?

<p>Ascending tracts carry sensory information from the body to the brain, while descending tracts transmit motor commands from the brain to the body. (D)</p> Signup and view all the answers

Why might the absence of the parachute reflex after 6-7 months post-birth raise concerns for a pediatrician?

<p>It may be a sign of delayed motor development or neurological impairment. (B)</p> Signup and view all the answers

What is the primary role of the third-order neuron in an ascending sensory pathway?

<p>To transmit sensory information from the thalamus to the cerebral cortex for conscious perception. (B)</p> Signup and view all the answers

How do gamma motor neurons contribute to muscle spindle function?

<p>They innervate intrafusal muscle fibers, adjusting their tension and sensitivity to stretch. (C)</p> Signup and view all the answers

Why are reflexes like the palmar grasp and rooting reflex present in infants but not typically in healthy adults?

<p>These reflexes are mediated by subcortical structures that are gradually inhibited by the developing cerebral cortex. (B)</p> Signup and view all the answers

What is the clinical significance of Babinski's sign in adults, and how does it relate to frontal lobe disorders?

<p>Babinski's sign suggests damage to the corticospinal tract, such as in frontal lobe disorders where inhibitory control is compromised. (D)</p> Signup and view all the answers

How does a sudden stretch impact the resultant contraction in the stretch reflex, and what neural mechanism underlies this phenomenon?

<p>A sudden stretch increases the magnitude of the contraction due to heightened activation of muscle spindles, resulting in increased alpha motor neuron firing. (D)</p> Signup and view all the answers

Which scenario exemplifies the most critical role of central pattern generators in the spinal cord?

<p>Facilitating repetitive muscle contractions during walking. (A)</p> Signup and view all the answers

During a rapid eccentric contraction (muscle lengthening under load), what is the MOST significant role of gamma motor neurons associated with muscle spindles?

<p>To maintain the tension and sensitivity of intrafusal fibers, allowing the spindle to detect changes in muscle length during the stretch. (D)</p> Signup and view all the answers

In a complex motor task requiring precise control and fine motor skills, such as playing the piano, where would you expect to find the highest density of muscle spindles?

<p>In the muscles of the fingers and hands. (A)</p> Signup and view all the answers

Which of the following represents the MOST accurate sequence of events in a typical spinal reflex arc?

<p>Stimulus → Receptor → Sensory neuron → Integration center → Motor neuron → Effector → Action (B)</p> Signup and view all the answers

Why are spinal reflexes characterized as involuntary, and what implications does this have for their execution?

<p>Spinal reflexes are not subject to conscious control; they are processed at the level of the spinal cord, allowing for rapid, automatic responses to stimuli. (B)</p> Signup and view all the answers

What is the functional significance of the distinction between primary and secondary sensory fibers within a muscle spindle?

<p>Primary fibers provide information about both the rate of change and the length of the muscle, whereas secondary fibers primarily provide information about muscle length. (C)</p> Signup and view all the answers

How does the concept of 'neural integration' within the spinal cord contribute to complex motor functions?

<p>By summating and processing both excitatory and inhibitory signals, allowing modulation of motor neuron activity and coordinated muscle actions. (A)</p> Signup and view all the answers

How would the disruption of gamma motor neuron function MOST directly impact motor control and proprioception?

<p>It would impair the ability of muscle spindles to detect changes in muscle length, especially during movement, leading to inaccurate proprioceptive feedback and motor incoordination. (C)</p> Signup and view all the answers

Considering the role of the spinal cord in both conduction and neural integration, how do these functions interact to produce a coordinated motor response to a sensory stimulus?

<p>Conduction carries sensory information to the integration center, where interneurons process the signal and modulate motor neuron activity to generate a context-appropriate response. (B)</p> Signup and view all the answers

Monosynaptic reflexes involve direct activation of a motor neuron by a sensory neuron, bypassing interneurons. How does this unique neural circuit influence the characteristics of the resulting reflex?

<p>It leads to a faster and more direct response, as the signal does not need to be processed through additional interneurons. (D)</p> Signup and view all the answers

A patient presents with selective damage to the medulla oblongata, specifically affecting decussation of sensory pathways. Which sensory deficit would MOST likely be observed as a direct result of this damage?

<p>Contralateral loss of fine touch sensation in the upper extremities. (B)</p> Signup and view all the answers

Why is the integration center considered a crucial component of the reflex arc?

<p>It analyzes sensory information and determines the appropriate motor response. (B)</p> Signup and view all the answers

A lesion completely transects the anterior spinocerebellar tract at the level of the lumbar spinal cord. Which functional deficit would MOST likely be observed in the patient?

<p>Impaired coordination and balance without conscious awareness. (A)</p> Signup and view all the answers

A patient suffers a stroke that selectively damages the lateral corticospinal tract in the right cerebral hemisphere. Which of the following deficits would MOST likely be observed?

<p>Contralateral deficits in fine motor control. (D)</p> Signup and view all the answers

What is the functional significance of the high density of muscle spindles in muscles responsible for fine motor control?

<p>Provides precise and rapid feedback about muscle length and changes in length. (A)</p> Signup and view all the answers

How do gamma motor neurons contribute to the sensitivity of muscle spindles, particularly during muscle shortening?

<p>By maintaining tension on intrafusal fibers, ensuring the spindle remains responsive. (C)</p> Signup and view all the answers

A patient exhibits impaired postural control and difficulty coordinating movements of the trunk. Which descending tract is MOST likely affected?

<p>Reticulospinal tract (C)</p> Signup and view all the answers

What would be the most likely effect of damage to central pattern generators in the spinal cord?

<p>Inability to perform rapid, alternating movements like running or swimming. (C)</p> Signup and view all the answers

Following a traumatic injury, a patient exhibits an inability to turn their head in response to sudden auditory or visual stimuli. Which descending tract is MOST likely compromised?

<p>Tectospinal tract (A)</p> Signup and view all the answers

How do primary and secondary sensory fibers within muscle spindles differ in their functional contributions?

<p>Primary fibers respond to both length and rate of change in length, while secondary fibers primarily indicate length. (C)</p> Signup and view all the answers

A patient has a lesion affecting the anterior corticospinal tract at the level of the cervical spinal cord. Which motor deficits would MOST likely result from this lesion?

<p>Weakness in axial muscles, affecting posture and balance. (D)</p> Signup and view all the answers

In the context of spinal reflexes, what is the functional significance of their involuntary nature?

<p>It enables rapid responses to stimuli, bypassing conscious processing for protection. (B)</p> Signup and view all the answers

A lesion selectively damages the lateral vestibulospinal tract. Which of the following deficits would be MOST anticipated?

<p>Difficulty maintaining balance in response to tilting. (D)</p> Signup and view all the answers

A patient experiences a spinal cord injury that selectively disrupts the spinothalamic tract. Which sensory deficit would MOST likely result from this injury?

<p>Loss of pain and temperature sensation on the contralateral side of the body. (B)</p> Signup and view all the answers

How does the absence of a spinal reflex typically present in infants, such as the Moro reflex, at a later developmental stage raise clinical concern?

<p>It suggests a potential issue with sensorimotor integration or neurological development. (A)</p> Signup and view all the answers

What role does the spinal cord play in neural integration, and how does this contribute to complex motor functions?

<p>It integrates sensory input with motor commands, allowing for modulated and coordinated responses. (A)</p> Signup and view all the answers

A patient presents with damage to the fasciculus cuneatus. Which specific sensory function would likely be compromised?

<p>Fine touch sensation from the upper limbs. (D)</p> Signup and view all the answers

Considering a patient with damage to the spinoreticular tract, which of the following clinical presentations would be the MOST expected?

<p>Altered levels of arousal and increased sensitivity to chronic pain. (B)</p> Signup and view all the answers

How does reciprocal inhibition contribute to the function of spinal reflexes, specifically during movements?

<p>It ensures smooth and coordinated movements by inhibiting the activity of antagonist muscles. (B)</p> Signup and view all the answers

What is the functional significance of the anatomical separation of sensory and motor pathways within the spinal cord?

<p>It prevents signal interference, ensuring efficient and specific communication between the brain and periphery. (A)</p> Signup and view all the answers

An adult patient with a known history of frontal lobe damage exhibits a pronounced palmar grasp reflex. What is the MOST likely explanation for this clinical finding?

<p>The frontal lobe damage has disinhibited primitive reflexes, allowing the palmar grasp reflex to re-emerge. (D)</p> Signup and view all the answers

During a neurological examination, an adult patient exhibits Babinski's sign. What does this finding suggest about the patient's neurological status?

<p>It suggests potential damage or dysfunction along the corticospinal tract. (D)</p> Signup and view all the answers

In a scenario where a person quickly steps on a sharp object, what is the MOST crucial role of the contralateral extension reflex that accompanies the flexor reflex?

<p>To maintain balance and support the body's weight as the opposite leg is flexed. (D)</p> Signup and view all the answers

What aspect of the stretch reflex is MOST immediately dependent on reciprocal inhibition?

<p>The relaxation of antagonist muscles to allow the desired movement to occur unimpeded. (A)</p> Signup and view all the answers

Why does the walking/stepping reflex typically disappear around 5-6 months of age in infants?

<p>Because of the maturation of higher-level motor control centers in the brain that inhibit the reflex. (B)</p> Signup and view all the answers

During rapid eccentric contraction, what is the MOST significant role of gamma motor neurons associated with muscle spindles?

<p>To maintain the sensitivity of the muscle spindle so it can detect changes in muscle length; preventing sensory saturation. (D)</p> Signup and view all the answers

First-order neurons in ascending sensory pathways serve what primary function?

<p>To relay sensory information from the periphery to the spinal cord or brainstem. (D)</p> Signup and view all the answers

What is the primary function of the third-order neuron in an ascending sensory pathway?

<p>To transmit sensory information from the thalamus to the cerebral cortex. (C)</p> Signup and view all the answers

Flashcards

Spinal Cord: Conduction

Pathways for sensory (ascending) and motor (descending) information to travel to/from the brain.

Spinal Cord: Neural Integration

The spinal cord integrates sensory input and generates motor output, e.g., bladder control.

Spinal Cord: Locomotion

The repetitive motor sequences such as walking are controlled by central pattern generators in the spinal cord.

Spinal Reflexes

Quick, involuntary responses to stimuli controlled by the spinal cord.

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Basic Reflex Arc Components

Stimulus, receptor, sensory neuron, integration center, motor neuron and effector.

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Monosynaptic Reflex

A reflex arc involving one synapse between the sensory and motor neuron.

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Polysynaptic Reflex

A reflex arc involving multiple synapses between the sensory and motor neuron.

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Muscle Spindles

Stretch receptors within muscles that detect changes in muscle length and movement.

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Proprioception

Awareness of body position and movement.

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Intrafusal Fibers

Specialized muscle fibers within the muscle spindle that control its sensitivity.

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Stretch Reflex

A muscle contraction in response to stretching within the muscle, mediated by the spinal cord, important for posture and stabilization.

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Synergists

Muscles that assist the prime mover (agonist) in performing a movement.

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Antagonists

Muscles that oppose the action of the agonist.

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Extensors

Muscles that extend or increase the angle at a joint.

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Flexors

Muscles that flex or decrease the angle at a joint.

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Flexor Reflex

A protective reflex in response to a painful stimulus, causing withdrawal of the limb.

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Contralateral Reflex Arc

A reflex arc involving sensory input from one side of the body and motor output to the opposite side.

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Ascending Tracts

Sensory pathways carrying information from the body to the brain.

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Sensation

The perception of light touch, pain, temperature, and pressure.

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Decussation

The point where nerve fibers cross over to the opposite side of the CNS.

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Cuneate Fasciculus

A sensory pathway responsible for fine touch and proprioception from the upper body.

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Spinothalamic Tract

A sensory pathway responsible for pain, temperature, and crude touch sensations.

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Spinoreticular Tract

A tract running from the spinal cord to the reticular formation, involved in pain sensation.

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Corticospinal Tract

A tract carrying motor information from the cortex to the spinal cord.

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Tectospinal Tract

A motor tract involved in head-turning reflexes in response to visual or auditory stimuli.

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Reticulospinal Tract

A motor tract influencing muscle tone, posture, and balance via the reticular formation.

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Vestibulospinal Tract

A motor tract that controls balance in response to gravity.

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Damaged structure

Provides positional sensation in the left arm & hand.

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Spinal Cord: Ascending Tracts

Carry sensory information up to the brain.

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Spinal Cord: Descending Tracts

Carry motor information down from the brain.

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Muscle Spindle: Function

Sensory receptor that detects muscle stretch.

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Gamma Motor Neurons

Motor neuron that innervates intrafusal muscle fibers.

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Intrafusal fibers: Location

Located near the ends of muscle. Few sarcomere at ends

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Gamma motor neurons: Function

Sensitivity during muscle shortening.

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Primary Sensory Fibers

Detects change in length and rate of change. Responsive to quick movements.

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Secondary Sensory Fibers

Detects change in length.

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Muscle Spindle: Motor output

Coordinate movement, regulate posture, corrective reflexes.

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Muscle Spindle: Sensory input

Muscle length, movement

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Anterior Spinocerebellar Tract

Unconscious Proprioception from lower limb and trunk.

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Dynamic Reflexes

Reflexes present in infants that disappear or integrate as the nervous system matures.

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Palmar grasp reflex

Infant reflex where the baby grasps an object placed in their palm.

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Moro reflex

Infant reflex triggered by a sudden loss of support, causing the baby to extend their arms and legs.

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First-Order Neuron

First neuron in the ascending pathway; detects stimulus and sends signal to spinal cord or brainstem.

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Study Notes

  • Study notes on reflexes, the spinal cord, and spinal tracts.

Spinal Cord

  • Conduction occurs with sensory information going up, and motor information going down
  • Neural integration occurs in the grey matter to control actions such as bladder control
  • Locomotion uses central pattern generators to create repetitive sequences like walking
  • Reflexes are included in spinal cord actions

Reflexes

  • Sensory neurons get stimulated by a receptor
  • Spinal reflex arcs are rapid and involuntary
  • The conscious though part of the brain makes decisions
  • Motor Neurons cause action effectors

Spinal Reflexes

  • Spinal reflexes are fast, only use a few neurons, and are involuntary
  • Spinal reflexes require stimulation, and are predictable

Reflex Components

  • Sensory receptor
  • Sensory neuron
  • Integration center
  • Motor neuron
  • Effector organ

Muscle Spindle

  • Stretch receptors include muscle spindles that have a high density in muscles; they involve fine motor control
  • Proprioception is the sensory input of muscle length and movement
  • Motor output results in contractions, coordinate movement, regulate posture, and corrective reflexes

Muscle Spindle Fibers

  • Intrafusal fibers are located near ends of the muscle, and have few sarcomere at the ends
  • Gamma motor fibers keep fibers taunt, with sensitivity during muscle shortening
  • Primary sensory fibers communicate length and rate, and are responsive to quick movements
  • Secondary sensory fibers sense length and sensory fiber synapses
  • Extrafusal fibers use alpha motor fibers

Muscle Spindle Actions

  • Muscle spindles do subconscious monitoring of posture, movement control, and corrective reflexes
  • The stretch reflex includes:
    • Contraction
    • Posture/stabilization
    • Equilibrium
  • Other actions include synergists, antagonists, extensors and flexors

Stretch Reflexes

  • Stretch reflexes are mediated by the brain, and include a spinal cord
  • Component and are stronger if there is a sudden stretch
  • Stretch reflexes depend on reciprocal inhibition

Flexor Reflexes

  • Flexor reflexes are enacted by an injurious stimulus, are polysynaptic, and cause flexor contraction
  • Flexor reflexes include weight bearing systems:
    • Ipsilateral and contralateral actions, and also extension of the opposite limb for balance

Contralateral Reflexes

  • Balance and support shifts to the opposite leg which extends

Developmentally Dynamic Reflexes

  • Palmar Grasp lasts until 5-6 months
  • Moro/ Startle lasts until 3-4 months
  • Rooting and sucking reflexes lasts until 4 months
  • Plantar reflex exhibits Babinski's sign under a year
  • Walking/Stepping integrates around ~5-6 months
  • Frontal release signs are released from inhibition, present in adults, and associated to frontal lobe disorder

Ascending Tracts

  • Sensory signals move upwards through 3 neurons
    • First order stimulus moves to the SC (spinal cord) or to the brainstem
    • Second order moves to the SC or brainstem thalamus(gateways, relay center)
    • Third order moves to the thalamus cerebral cortex

Ascending Tract Sensations

  • Leg and trunk sensation and position, plus arm sensation and position
  • Muscle feedback for balance/position
  • Sensation of light touch, pain, temperature, and pressure

Path to CNS

  • Signals go to the cuneate fasciculus and exhibit decussation
  • Fasciculi can go to the medulla
  • The spinothalamic goes to the spinal cord (SC))
  • Spinoreticular goes to the SC
  • The ant. spinocerebellar goes to he SC and Post.

Descending Tracts

  • Fine limb movement
  • Limbs, posture control
  • Turning head reflex
  • Respond to tilt and keep balance

Path to CNS

  • Pathway uses corticospinal tracts
    • Lat. corticospinal goes to the medulla
    • Ant. corticospinal goes to the SC
    • Tectospinal goes to the midbrain
    • Reticulospinal goes to none
    • Lat. vestibulospinal goes to none
    • Med. vestibulospinal

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Description

Study notes covering reflexes, spinal cord functions like conduction and neural integration, and spinal tracts. Explores spinal reflex arcs, muscle spindles, and their components. Includes sensory and motor neurons.

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