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Questions and Answers
What is the function of hemoglobin in red blood cells?
What is the function of hemoglobin in red blood cells?
Which of the following characteristics is NOT true of red blood cells?
Which of the following characteristics is NOT true of red blood cells?
What is the primary function of red blood cells?
What is the primary function of red blood cells?
What percentage of circulating red blood cells are replaced each day?
What percentage of circulating red blood cells are replaced each day?
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Why is the lifespan of red blood cells relatively short?
Why is the lifespan of red blood cells relatively short?
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What happens to red blood cells at the end of their lifespan?
What happens to red blood cells at the end of their lifespan?
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What is the significance of the biconcave shape of red blood cells?
What is the significance of the biconcave shape of red blood cells?
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What is the approximate total surface area of an adult's red blood cells?
What is the approximate total surface area of an adult's red blood cells?
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What is the term for the dangerous clumps/fragments of red blood cells (RBCs) that can block small blood vessels?
What is the term for the dangerous clumps/fragments of red blood cells (RBCs) that can block small blood vessels?
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What is the significance of the 'Rh' in the Rh blood group?
What is the significance of the 'Rh' in the Rh blood group?
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Why can an incompatible blood transfusion be dangerous?
Why can an incompatible blood transfusion be dangerous?
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What is the difference between Rh positive and Rh negative individuals?
What is the difference between Rh positive and Rh negative individuals?
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Which of the following blood types is characterized by the absence of the Rh surface antigen?
Which of the following blood types is characterized by the absence of the Rh surface antigen?
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Which ethnic group has the highest percentage of individuals with blood type O?
Which ethnic group has the highest percentage of individuals with blood type O?
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Which ethnic group has the lowest percentage of individuals with blood type AB?
Which ethnic group has the lowest percentage of individuals with blood type AB?
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Which ethnic group has the highest percentage of individuals with Rh positive blood?
Which ethnic group has the highest percentage of individuals with Rh positive blood?
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What happens to the heme portion of hemoglobin when red blood cells are broken down?
What happens to the heme portion of hemoglobin when red blood cells are broken down?
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Which of the following explains the yellow-brown color of feces?
Which of the following explains the yellow-brown color of feces?
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What condition is indicated by the presence of intact red blood cells in urine?
What condition is indicated by the presence of intact red blood cells in urine?
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Which of these is NOT a substance that can cause an immune response and is recognized as foreign by the immune system?
Which of these is NOT a substance that can cause an immune response and is recognized as foreign by the immune system?
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What are the three most important blood cell surface antigens for determining blood type?
What are the three most important blood cell surface antigens for determining blood type?
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What is the term for the clumping of red blood cells that occurs when surface antigens are exposed to corresponding antibodies?
What is the term for the clumping of red blood cells that occurs when surface antigens are exposed to corresponding antibodies?
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Which of the following is an example of how giving type A blood to a patient who is type B could cause a harmful reaction?
Which of the following is an example of how giving type A blood to a patient who is type B could cause a harmful reaction?
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How would a liver disease affect the level of bilirubin in the blood?
How would a liver disease affect the level of bilirubin in the blood?
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What is not a component of the cardiovascular system?
What is not a component of the cardiovascular system?
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Which function is associated with the transportation of metabolic wastes?
Which function is associated with the transportation of metabolic wastes?
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How does blood help regulate pH in interstitial fluids?
How does blood help regulate pH in interstitial fluids?
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What role does blood play in injury response?
What role does blood play in injury response?
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Which type of blood vessels are primarily responsible for transporting blood back to the heart?
Which type of blood vessels are primarily responsible for transporting blood back to the heart?
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What is the primary function of capillaries?
What is the primary function of capillaries?
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What type of cells does blood transport to help defend against infection?
What type of cells does blood transport to help defend against infection?
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Which statement accurately describes the function of arteries?
Which statement accurately describes the function of arteries?
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What is erythropoiesis?
What is erythropoiesis?
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Where does erythropoiesis primarily occur?
Where does erythropoiesis primarily occur?
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What happens to erythroblasts during the RBC development process?
What happens to erythroblasts during the RBC development process?
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What occurs in macrophages concerning old RBCs?
What occurs in macrophages concerning old RBCs?
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What is hemoglobinuria?
What is hemoglobinuria?
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Which protein binds iron after it is stripped from heme units?
Which protein binds iron after it is stripped from heme units?
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What is a potential effect of blocked bile ducts?
What is a potential effect of blocked bile ducts?
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What is the primary trigger for the release of erythropoietin (EPO)?
What is the primary trigger for the release of erythropoietin (EPO)?
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Which condition does NOT stimulate the release of erythropoietin (EPO)?
Which condition does NOT stimulate the release of erythropoietin (EPO)?
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What type of cells do myeloid stem cells primarily produce?
What type of cells do myeloid stem cells primarily produce?
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What elements are involved in a complete blood count (CBC)?
What elements are involved in a complete blood count (CBC)?
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Which of the following describes the recycling of aged or damaged red blood cells?
Which of the following describes the recycling of aged or damaged red blood cells?
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What is the clinical significance of blood typing?
What is the clinical significance of blood typing?
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Which type of white blood cell is responsible for fighting infection?
Which type of white blood cell is responsible for fighting infection?
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Flashcards
Erythropoietin (EPO)
Erythropoietin (EPO)
A hormone released in response to low oxygen levels in tissues.
Hypoxia
Hypoxia
A condition of low oxygen levels in tissues.
Stimuli for EPO release
Stimuli for EPO release
Factors that trigger EPO production include anemia, low blood flow to kidneys, and lung issues.
Stem cells in red bone marrow
Stem cells in red bone marrow
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Hematology
Hematology
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Complete Blood Count (CBC)
Complete Blood Count (CBC)
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ABO blood typing
ABO blood typing
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Hemolytic disease of the newborn
Hemolytic disease of the newborn
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Urobilins and Stercobilins
Urobilins and Stercobilins
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Kidneys' role in RBC breakdown
Kidneys' role in RBC breakdown
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Hematuria
Hematuria
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Blood Type Determinants
Blood Type Determinants
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ABO Blood Group
ABO Blood Group
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Agglutination
Agglutination
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Red Blood Cell Count
Red Blood Cell Count
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Shape of RBCs
Shape of RBCs
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Bilirubin in Liver Disease
Bilirubin in Liver Disease
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Surface Area-to-Volume Ratio
Surface Area-to-Volume Ratio
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Surface Antigens
Surface Antigens
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Rouleaux Formation
Rouleaux Formation
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Flexible RBCs
Flexible RBCs
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Anucleate RBCs
Anucleate RBCs
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RBC Lifespan
RBC Lifespan
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RBC Replacement Rate
RBC Replacement Rate
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Components of cardiovascular system
Components of cardiovascular system
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Function of blood - Transport
Function of blood - Transport
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Oxygen transport
Oxygen transport
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Carbon dioxide transport
Carbon dioxide transport
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Regulation of pH
Regulation of pH
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Clotting mechanism
Clotting mechanism
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Defense against pathogens
Defense against pathogens
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Arteries and veins
Arteries and veins
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Cross-reaction
Cross-reaction
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Hemolysis
Hemolysis
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Rh blood group
Rh blood group
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Rh positive
Rh positive
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Rh negative
Rh negative
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Blood type distribution
Blood type distribution
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Percentage with Rh plus
Percentage with Rh plus
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Erythropoiesis
Erythropoiesis
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Location of Erythropoiesis
Location of Erythropoiesis
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Reticulocytes
Reticulocytes
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Function of Macrophages
Function of Macrophages
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Iron in RBC breakdown
Iron in RBC breakdown
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Hemoglobinuria
Hemoglobinuria
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Jaundice
Jaundice
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Study Notes
Chapter 17: Blood
- Blood is a fluid connective tissue
- Whole blood comprises plasma and formed elements
- Plasma (55%): mostly water, proteins (albumins, globulins, fibrinogen), and other solutes
- 60% plasma proteins—osmotic pressure
- 35% globulins—Immunoglobulins (antibodies); transport globulins
- 4% fibrinogen—blood clotting
- 1% other solutes—electrolytes, nutrients, wastes
- Formed elements (45%): red blood cells, white blood cells, and platelets
- Red blood cells (erythrocytes): ~99.9% formed elements—oxygen transport
- White blood cells (leukocytes): less than 0.1%—body defense; five classes
- Platelets: less than 0.1%—blood clotting
Cardiovascular System
- Consists of heart, blood vessels, and blood
- Heart: pumps blood; maintains blood pressure
- Blood vessels: arteries, capillaries, and veins
- Arteries: carry blood away from the heart
- Capillaries: permit exchange between blood and interstitial fluids
- Veins: return blood to the heart
Blood Functions
- Transport dissolved gases, nutrients, hormones, and metabolic wastes
- Oxygen from lungs to tissues
- Carbon dioxide from tissues to lungs
- Nutrients from digestive tract to tissues
- Hormones from glands to target tissues
- Wastes to kidneys for excretion
- Regulate pH and ion composition of interstitial fluids
- Restrict fluid loss at injury sites
- Defend against toxins and pathogens
- Stabilize body temperature
Hematology
- Study of blood and blood-forming tissues
- Complete blood count (CBC): various tests to assess blood (RBC count, WBC count, hemoglobin, hematocrit)
- Red blood cell tests (assessing number, size, shape, maturity)
Blood Typing
- Determined by surface antigens on red blood cells
- ABO antigens: A, B, O
- Rh antigen: Rh+ or Rh-
- Blood typing tests: mixing blood with antibodies to specific antigens for clumping determination; crucial for safe transfusions
- Blood type compatibility: crucial to avoid transfusion reactions
Hemolytic Disease of the Newborn (HDN)
- Condition where maternal antibodies harm fetal red blood cells
- Often a result of Rh incompatibility between mother and fetus
- Sensitization of the mother to Rh antigens during first pregnancy
- Subsequent pregnancies may lead to the destruction of fetal red blood cells
- Prevention with RhoGAM injections
White Blood Cells
- Types: neutrophils, eosinophils, basophils, lymphocytes, and monocytes
- Neutrophils: 50-70% - phagocytic (engulfing debris)
- Eosinophils: 2-4% - phagocytic; respond to parasitic infections and allergies
- Basophils: <1% - release histamine and other chemicals that promote inflammation
- Lymphocytes: 20-40% - part of lymphatic system; involved in specific defense mechanisms
- Monocytes: 2-8% - move into tissues to become macrophages which engulf pathogens
Hemostasis
- Process of stopping blood loss
- Three phases:
- Vascular phase: endothelial cells release chemicals, causing vascular spasms and membrane "stickiness"
- Platelet phase: platelets adhere to damaged vessel surfaces, aggregating and releasing chemicals further promoting vasoconstriction and hemostasis.
- Coagulation phase: conversion of soluble fibrinogen into insoluble fibrin forming a blood clot.
- Fibrinolysis: process of clot dissolving initiated by tissue plasminogen activator
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Description
Test your knowledge on the functions and characteristics of red blood cells. This quiz covers aspects including hemoglobin function, red blood cell lifespan, and blood group significance. Perfect for students studying human biology or healthcare related subjects.