Guyton 33 book. Red Blood Cells and Anemia Quiz

<p>Intermediate-stage cells are committed to a specific cell lineage, while multipotential stem cells are not. (A)</p> Signup and view all the answers

<p>CFU-GM (C)</p> Signup and view all the answers

<p>Colony formation (A)</p> Signup and view all the answers

<p>Bone marrow (B)</p> Signup and view all the answers

<p>They are only found in the bone marrow. (D)</p> Signup and view all the answers

<p>Vertebrae (C)</p> Signup and view all the answers

<p>It becomes fatty and ceases RBC production. (C)</p> Signup and view all the answers

<p>CFU-L (B)</p> Signup and view all the answers

<p>Generating all circulating blood cells. (D)</p> Signup and view all the answers

<p>To ensure continued production of new blood cells. (D)</p> Signup and view all the answers

<p>They decrease gradually. (D)</p> Signup and view all the answers

<p>Flexible and disc-shaped, with a slight indentation. (C)</p> Signup and view all the answers

<p>They contribute to a small amount of red blood cell production. (B)</p> Signup and view all the answers

<p>CFU-E (A)</p> Signup and view all the answers

<p>Megakaryocytes (B)</p> Signup and view all the answers

<p>All of the above (D)</p> Signup and view all the answers

<p>MHSC (C)</p> Signup and view all the answers

<p>CFU-M (B)</p> Signup and view all the answers

<p>CFU-M (C)</p> Signup and view all the answers

<p>MHSC -&gt; CFU-S -&gt; CFU-B -&gt; CFU-E -&gt; Erythrocyte (A)</p> Signup and view all the answers

<p>Growth inducers (C)</p> Signup and view all the answers

<p>Blood volume is greatly increased. (C)</p> Signup and view all the answers

<p>Cardiac output remains close to normal. (B)</p> Signup and view all the answers

<p>Blood pressure-regulating mechanisms. (B)</p> Signup and view all the answers

<p>Extreme tissue hypoxia and possible cardiac failure. (A)</p> Signup and view all the answers

<p>Arterial pressure is generally normal. (C)</p> Signup and view all the answers

<p>Hypoxia from too little oxygen in the air. (B)</p> Signup and view all the answers

<p>Increases blood quantity in the subpapillary venous plexus. (D)</p> Signup and view all the answers

<p>Hypertension develops. (A)</p> Signup and view all the answers

<p>RBC concentration returns to normal within 3 to 6 weeks (D)</p> Signup and view all the answers

<p>Hemoglobin S (D)</p> Signup and view all the answers

<p>They are smaller and spherical instead of biconcave (B)</p> Signup and view all the answers

<p>Insufficient absorption of iron from the intestines (A)</p> Signup and view all the answers

<p>RBCs are much smaller and contain too little hemoglobin (C)</p> Signup and view all the answers

<p>Exposure to high-dose radiation or certain chemicals (D)</p> Signup and view all the answers

<p>Exposure to low concentrations of oxygen (A)</p> Signup and view all the answers

<p>They are ruptured by slight compression (A)</p> Signup and view all the answers

<p>Macrophages absorb iron from hemoglobin and release it back into the blood. (B)</p> Signup and view all the answers

<p>Iron supplements (D)</p> Signup and view all the answers

<p>Transferrin interacts with receptors on intestinal epithelial cells to facilitate iron absorption. (D)</p> Signup and view all the answers

<p>Macrophages convert the porphyrin portion of hemoglobin into bilirubin through a series of stages. (D)</p> Signup and view all the answers

<p>Ferritin is a storage form of iron, whereas transferrin transports iron in the blood. (A)</p> Signup and view all the answers

<p>Increased production of red blood cells. (D)</p> Signup and view all the answers

<p>Apotransferrin combines with iron to form transferrin. (B)</p> Signup and view all the answers

<p>The iron released from hemoglobin is used in the synthesis of new red blood cells. (A)</p> Signup and view all the answers

A protein secreted by the liver that binds iron in the bile.

A combination of apotransferrin and iron, responsible for iron transport in the blood.

Macrophages in the liver that help destroy hemoglobin.

The process of hemoglobin breakdown by macrophages after RBCs burst.

The uptake of iron from the small intestine into the bloodstream.

A bile pigment derived from the breakdown of hemoglobin by macrophages.

A protein that stores iron in the liver and other tissues.

A condition marked by a deficiency of hemoglobin in the blood.

Cells similar to multipotential stem cells but committed to a specific lineage.

Stem cells that are destined to become a specific type of cell.

Cells that can proliferate into specific types of mature blood cells when cultured.

A committed stem cell that specifically produces erythrocytes (red blood cells).

Colony-forming unit for granulocytes and monocytes in blood cell culture.

Red blood cells responsible for carrying oxygen.

A type of white blood cell involved in immune response.

Large white blood cells that differentiate into macrophages.

The process by which erythrocytes are formed in the bone marrow, varying with age and influenced by growth inducers.

Proteins that regulate the growth and reproduction of stem cells.

Multipotent hematopoietic stem cell, a type of stem cell capable of differentiating into various blood cells.

Large bone marrow cells that produce platelets necessary for blood clotting.

A type of anemia caused by rapid loss of blood, leading to low RBC concentration.

A hereditary condition where RBCs are small and spherical instead of biconcave discs.

Anemia characterized by smaller than normal RBCs with insufficient hemoglobin due to chronic blood loss.

A genetic form of anemia where RBCs form abnormal sickle shapes due to hemoglobin S.

An abnormal type of hemoglobin found in sickle cell anemia, leading to cell deformation under low oxygen.

A condition characterized by the lack of functional bone marrow often leading to anemia.

Exposure that can lead to bone marrow dysfunction and subsequent aplastic anemia.

Persistent loss of blood that causes the body to struggle in replacing iron and hemoglobin quickly.

A condition characterized by increased red blood cell volume, often leading to increased blood viscosity.

In polycythemia, blood flow may increase but cardiac output remains near normal due to blood viscosity effects.

In polycythemia, cardiac output does not significantly increase despite increased blood flow demands.

A condition where tissues lack sufficient oxygen, often a risk during severe exercise in anemic patients.

Many individuals with polycythemia have normal arterial pressure; however, some may experience elevated pressure.

Occurs when tissues are hypoxic due to low oxygen environments or inadequate oxygen delivery, stimulating red blood cell production.

A network of veins just under the skin which contributes to skin color; its blood volume increases in polycythemia vera.

Red blood cells (RBCs) are primarily produced in the liver during early gestation and later in bone marrow.

These are stem cells in the bone marrow that can differentiate into various blood cells.

Bone marrow production of RBCs decreases significantly after age 20.

These bones primarily produce RBCs in childhood but become fatty and less productive with age.

Beyond a certain age, the marrow in long bones turns fatty and is less effective in producing RBCs.

Bones such as the vertebrae and sternum continue producing RBCs even as other marrow becomes less productive.

RBCs are produced from stem cells and eventually differentiate into various blood cell types.

With increasing age, the overall production of RBCs diminishes.