Y1S1 003 III Physiology Red Blood Cell

In which condition are leptocytes typically seen?

Cancer that has spread to the bone marrow
Conditions causing excessive production of hemoglobin
Erythroblastosis fetalis
Thalassemias (correct)

What percentage of glucose is metabolized by the pentose phosphate pathway in red blood cells?

30%
10% (correct)
5%
20%

What is the function of the MCHC test?

Measuring the average amount of hemoglobin in each red blood cell
Calculating the concentration of hemoglobin in a single red blood cell (correct)
Describing the size of red blood cells
Determining the ratio of red blood cells to total blood volume

What is the primary function of the hexose monophosphate shunt in red blood cells?

To provide reducing power to protect RBCs from oxidative stress (B) Signup and view all the answers

What is the name of the parameter that measures the ratio of red blood cells to total blood volume?

Haematocrit (A) Signup and view all the answers

What is the net gain of ATP for every mole of glucose metabolized in red blood cells?

2 moles of ATP (B) Signup and view all the answers

In which condition may normoblasts be seen?

All of the above (D) Signup and view all the answers

What is the name of the parameter that measures the average amount of hemoglobin in each red blood cell?

Mean Corpuscular Haemoglobin (D) Signup and view all the answers

What is the role of G6PD in red blood cells?

To protect cells from oxidant stress (C) Signup and view all the answers

What is the most common triggers of hemolysis in G6PD deficiency?

Antimalarials and analgesics (D) Signup and view all the answers

What is the method used to determine Haematocrit?

Centrifugation (A) Signup and view all the answers

What is the primary site of action of 2,3-DPG in red blood cells?

Hemoglobin molecule (B) Signup and view all the answers

What is the primary function of erythrocytes in the human body?

To transport oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs (D) Signup and view all the answers

What is the characteristic shape of mature erythrocytes?

Biconcave disc (D) Signup and view all the answers

Which organelles are absent in mature erythrocytes?

Ribosomes, mitochondria, and other organelles typical of most body cells (B) Signup and view all the answers

What is the approximate number of hemoglobin molecules in a mature erythrocyte?

200,000 to 300,000 (A) Signup and view all the answers

What is the primary mechanism of metabolism in immature erythrocytes?

Tricarboxylic Acid (TCA) cycle and electron transfer chain (B) Signup and view all the answers

What is the fate of pyruvate in mature erythrocytes?

It is converted to lactate (A) Signup and view all the answers

What is the primary source of iron for daily hemoglobin synthesis?

Breakdown of senescent RBCs (C) Signup and view all the answers

What is the effect of haeme accumulation on protoporphyrin synthesis?

It decreases protoporphyrin synthesis through feedback inhibition (A) Signup and view all the answers

What is the approximate percentage of HbF in adult hemoglobin?

0.5-0.8% (C) Signup and view all the answers

What is the function of heme in hemoglobin?

To transport oxygen (C) Signup and view all the answers

What is the characteristic of carboxyhemoglobin?

It has a 218 times greater affinity to CO than O2 (A) Signup and view all the answers

What is the primary characteristic of hemoglobinopathies?

Abnormalities in globin production (B) Signup and view all the answers

What is the normal range of Packed Cell Volume (PCV) or Hematocrit in females?

36 - 46% (A) Signup and view all the answers

What is the process by which blood cells enter the circulation?

Diapedesis (A) Signup and view all the answers

What is the primary purpose of a platelet count test?

Diagnosing bleeding disorders (D) Signup and view all the answers

What is the minimum percentage of reticulocyte count required to indicate increased erythropoietic activity?

2.5% (C) Signup and view all the answers

What is the compound that binds with an atom of iron to form haeme?

Protoporphyrin (C) Signup and view all the answers

What is the only component that a developing normoblast lacks to make haemoglobin?

Iron (C) Signup and view all the answers