Y1S1 003 III Physiology Red Blood Cell

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Questions and Answers

In which condition are leptocytes typically seen?

  • Cancer that has spread to the bone marrow
  • Conditions causing excessive production of hemoglobin
  • Erythroblastosis fetalis
  • Thalassemias (correct)

What percentage of glucose is metabolized by the pentose phosphate pathway in red blood cells?

  • 30%
  • 10% (correct)
  • 5%
  • 20%

What is the function of the MCHC test?

  • Measuring the average amount of hemoglobin in each red blood cell
  • Calculating the concentration of hemoglobin in a single red blood cell (correct)
  • Describing the size of red blood cells
  • Determining the ratio of red blood cells to total blood volume

What is the primary function of the hexose monophosphate shunt in red blood cells?

<p>To provide reducing power to protect RBCs from oxidative stress (B)</p> Signup and view all the answers

What is the name of the parameter that measures the ratio of red blood cells to total blood volume?

<p>Haematocrit (A)</p> Signup and view all the answers

What is the net gain of ATP for every mole of glucose metabolized in red blood cells?

<p>2 moles of ATP (B)</p> Signup and view all the answers

In which condition may normoblasts be seen?

<p>All of the above (D)</p> Signup and view all the answers

What is the name of the parameter that measures the average amount of hemoglobin in each red blood cell?

<p>Mean Corpuscular Haemoglobin (D)</p> Signup and view all the answers

What is the role of G6PD in red blood cells?

<p>To protect cells from oxidant stress (C)</p> Signup and view all the answers

What is the most common triggers of hemolysis in G6PD deficiency?

<p>Antimalarials and analgesics (D)</p> Signup and view all the answers

What is the method used to determine Haematocrit?

<p>Centrifugation (A)</p> Signup and view all the answers

What is the primary site of action of 2,3-DPG in red blood cells?

<p>Hemoglobin molecule (B)</p> Signup and view all the answers

What is the primary function of erythrocytes in the human body?

<p>To transport oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs (D)</p> Signup and view all the answers

What is the characteristic shape of mature erythrocytes?

<p>Biconcave disc (D)</p> Signup and view all the answers

Which organelles are absent in mature erythrocytes?

<p>Ribosomes, mitochondria, and other organelles typical of most body cells (B)</p> Signup and view all the answers

What is the approximate number of hemoglobin molecules in a mature erythrocyte?

<p>200,000 to 300,000 (A)</p> Signup and view all the answers

What is the primary mechanism of metabolism in immature erythrocytes?

<p>Tricarboxylic Acid (TCA) cycle and electron transfer chain (B)</p> Signup and view all the answers

What is the fate of pyruvate in mature erythrocytes?

<p>It is converted to lactate (A)</p> Signup and view all the answers

What is the primary source of iron for daily hemoglobin synthesis?

<p>Breakdown of senescent RBCs (C)</p> Signup and view all the answers

What is the effect of haeme accumulation on protoporphyrin synthesis?

<p>It decreases protoporphyrin synthesis through feedback inhibition (A)</p> Signup and view all the answers

What is the approximate percentage of HbF in adult hemoglobin?

<p>0.5-0.8% (C)</p> Signup and view all the answers

What is the function of heme in hemoglobin?

<p>To transport oxygen (C)</p> Signup and view all the answers

What is the characteristic of carboxyhemoglobin?

<p>It has a 218 times greater affinity to CO than O2 (A)</p> Signup and view all the answers

What is the primary characteristic of hemoglobinopathies?

<p>Abnormalities in globin production (B)</p> Signup and view all the answers

What is the normal range of Packed Cell Volume (PCV) or Hematocrit in females?

<p>36 - 46% (A)</p> Signup and view all the answers

What is the process by which blood cells enter the circulation?

<p>Diapedesis (A)</p> Signup and view all the answers

What is the primary purpose of a platelet count test?

<p>Diagnosing bleeding disorders (D)</p> Signup and view all the answers

What is the minimum percentage of reticulocyte count required to indicate increased erythropoietic activity?

<p>2.5% (C)</p> Signup and view all the answers

What is the compound that binds with an atom of iron to form haeme?

<p>Protoporphyrin (C)</p> Signup and view all the answers

What is the only component that a developing normoblast lacks to make haemoglobin?

<p>Iron (C)</p> Signup and view all the answers

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