30 Questions
In which condition are leptocytes typically seen?
Thalassemias
What percentage of glucose is metabolized by the pentose phosphate pathway in red blood cells?
10%
What is the function of the MCHC test?
Calculating the concentration of hemoglobin in a single red blood cell
What is the primary function of the hexose monophosphate shunt in red blood cells?
To provide reducing power to protect RBCs from oxidative stress
What is the name of the parameter that measures the ratio of red blood cells to total blood volume?
Haematocrit
What is the net gain of ATP for every mole of glucose metabolized in red blood cells?
2 moles of ATP
In which condition may normoblasts be seen?
All of the above
What is the name of the parameter that measures the average amount of hemoglobin in each red blood cell?
Mean Corpuscular Haemoglobin
What is the role of G6PD in red blood cells?
To protect cells from oxidant stress
What is the most common triggers of hemolysis in G6PD deficiency?
Antimalarials and analgesics
What is the method used to determine Haematocrit?
Centrifugation
What is the primary site of action of 2,3-DPG in red blood cells?
Hemoglobin molecule
What is the primary function of erythrocytes in the human body?
To transport oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs
What is the characteristic shape of mature erythrocytes?
Biconcave disc
Which organelles are absent in mature erythrocytes?
Ribosomes, mitochondria, and other organelles typical of most body cells
What is the approximate number of hemoglobin molecules in a mature erythrocyte?
200,000 to 300,000
What is the primary mechanism of metabolism in immature erythrocytes?
Tricarboxylic Acid (TCA) cycle and electron transfer chain
What is the fate of pyruvate in mature erythrocytes?
It is converted to lactate
What is the primary source of iron for daily hemoglobin synthesis?
Breakdown of senescent RBCs
What is the effect of haeme accumulation on protoporphyrin synthesis?
It decreases protoporphyrin synthesis through feedback inhibition
What is the approximate percentage of HbF in adult hemoglobin?
0.5-0.8%
What is the function of heme in hemoglobin?
To transport oxygen
What is the characteristic of carboxyhemoglobin?
It has a 218 times greater affinity to CO than O2
What is the primary characteristic of hemoglobinopathies?
Abnormalities in globin production
What is the normal range of Packed Cell Volume (PCV) or Hematocrit in females?
36 - 46%
What is the process by which blood cells enter the circulation?
Diapedesis
What is the primary purpose of a platelet count test?
Diagnosing bleeding disorders
What is the minimum percentage of reticulocyte count required to indicate increased erythropoietic activity?
2.5%
What is the compound that binds with an atom of iron to form haeme?
Protoporphyrin
What is the only component that a developing normoblast lacks to make haemoglobin?
Iron
Test your knowledge of red blood cell physiology, covering topics such as metabolism, haemoglobin synthesis, characteristics, and disorders like anaemia and haemoglobinopathies. This quiz is perfect for students of biology, medicine, and healthcare professionals. Assess your understanding of erythrocytes, leukocytes, and thrombocytes and their functions in the human body.
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