Podcast
Questions and Answers
What is the term for red blood cells that have a irregular shape and are fragmented?
What is the term for red blood cells that have a irregular shape and are fragmented?
- Acanthocytic
- Hypochromic
- Crenated
- Dysmorphic (correct)
What can be used to lyse RBCs and provide clear observation of yeast, oil droplets, and WBCs?
What can be used to lyse RBCs and provide clear observation of yeast, oil droplets, and WBCs?
- Starch
- Reagent strips
- Supravital staining
- Acetic acid (correct)
What is the normal value for red blood cells per high power field (hpf)?
What is the normal value for red blood cells per high power field (hpf)?
- 0-5/hpf
- 5-10/hpf
- 0-2 to 3/hpf (correct)
- 10-15/hpf
What is the term for red blood cells that are non-nucleated and biconcave in shape?
What is the term for red blood cells that are non-nucleated and biconcave in shape?
What is associated with an increased number of red blood cells?
What is associated with an increased number of red blood cells?
What is the term for red blood cells that appear as ghost cells?
What is the term for red blood cells that appear as ghost cells?
Which of the following is characterized by refractility and possible different plane?
Which of the following is characterized by refractility and possible different plane?
What is the significance of observing crenated RBCs in a sample?
What is the significance of observing crenated RBCs in a sample?
What is the purpose of supravital staining?
What is the purpose of supravital staining?
What is the significance of observing starch in a sample?
What is the significance of observing starch in a sample?
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Study Notes
Red Blood Cells (RBCs)
- Smooth, non-nucleated biconcave disks in shape
- Can be classified into different types based on appearance and urine conditions:
- Crenated RBCs: seen in hypertonic/hypersthenuric urine
- Ghost cells: seen in hypotonic/hyposthenuric urine
- Dysmorphic RBCs: indicative of glomerular membrane damage, often fragmented, hypochromic, acanthocytic, or with blebs
- Aids in diagnosis and indicates glomerular bleeding
- Can be affected by strenuous exercise
Yeast, Oil Droplets, and Air Bubbles
- Yeast: identified by buddings, can be confirmed by lysing RBCs with acetic acid
- Oil droplets: highly refractile, can be confirmed by lysing RBCs with acetic acid
- Air bubbles: exhibit refractility and may appear in a different plane
Starch and Reagent Strip Correlation
- Starch: refractile and polarizes
- Reagent strip correlation: helpful in confirming observations
Importance of RBC Count
- Normal value: 0-2 to 3/hpf
- Increased RBC count associated with:
- Damage to glomerular membrane
- Vascular injury to genitourinary tract
- Renal calculi
- Number of cells indicates extent of damage
Red Blood Cells (RBCs)
- Smooth, non-nucleated biconcave disks in shape
- Can be classified into different types based on appearance and urine conditions:
- Crenated RBCs: seen in hypertonic/hypersthenuric urine
- Ghost cells: seen in hypotonic/hyposthenuric urine
- Dysmorphic RBCs: indicative of glomerular membrane damage, often fragmented, hypochromic, acanthocytic, or with blebs
- Aids in diagnosis and indicates glomerular bleeding
- Can be affected by strenuous exercise
Yeast, Oil Droplets, and Air Bubbles
- Yeast: identified by buddings, can be confirmed by lysing RBCs with acetic acid
- Oil droplets: highly refractile, can be confirmed by lysing RBCs with acetic acid
- Air bubbles: exhibit refractility and may appear in a different plane
Starch and Reagent Strip Correlation
- Starch: refractile and polarizes
- Reagent strip correlation: helpful in confirming observations
Importance of RBC Count
- Normal value: 0-2 to 3/hpf
- Increased RBC count associated with:
- Damage to glomerular membrane
- Vascular injury to genitourinary tract
- Renal calculi
- Number of cells indicates extent of damage
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