Podcast
Questions and Answers
What is the main purpose of rectal dosage forms intended for local effect?
What is the main purpose of rectal dosage forms intended for local effect?
- Improving taste perception
- Treating systemic conditions
- Managing haemorrhoids (correct)
- Combating viral infections
Which type of drugs are commonly included in rectal dosage forms for local effect?
Which type of drugs are commonly included in rectal dosage forms for local effect?
- Antibiotics and antifungals
- Antihypertensives and anticoagulants
- Astringents and local anaesthetics (correct)
- Corticosteroids and bronchodilators
What is the most commonly used type of rectal dosage form?
What is the most commonly used type of rectal dosage form?
- Enemas
- Rectal foams
- Capsules
- Suppositories (correct)
How are rectal suppositories described in terms of their preparation?
How are rectal suppositories described in terms of their preparation?
Which type of bases are commonly used in formulating rectal suppositories for hydrophilic drugs?
Which type of bases are commonly used in formulating rectal suppositories for hydrophilic drugs?
What is a key characteristic of the ideal suppository base?
What is a key characteristic of the ideal suppository base?
What is the main reason for the lower rate and extent of drug absorption in the rectum compared to the oral route?
What is the main reason for the lower rate and extent of drug absorption in the rectum compared to the oral route?
Why is rectal drug delivery considered a safe route of drug administration?
Why is rectal drug delivery considered a safe route of drug administration?
Why is the rectal route suitable for drugs that are liable to degrade in the gastrointestinal tract (GIT)?
Why is the rectal route suitable for drugs that are liable to degrade in the gastrointestinal tract (GIT)?
Which patient group finds rectal dosage forms less acceptable for long-term therapy?
Which patient group finds rectal dosage forms less acceptable for long-term therapy?
In rectal drug delivery, what factor can lead to an increase in first-pass metabolism if incorrectly positioned?
In rectal drug delivery, what factor can lead to an increase in first-pass metabolism if incorrectly positioned?
Why is rectal drug delivery suitable for pediatric patients?
Why is rectal drug delivery suitable for pediatric patients?
Which of the following statements about rectal drug delivery is correct?
Which of the following statements about rectal drug delivery is correct?
Which of the following conditions is most suitable for rectal drug delivery?
Which of the following conditions is most suitable for rectal drug delivery?
What is the primary mechanism of drug absorption following rectal administration?
What is the primary mechanism of drug absorption following rectal administration?
Which of the following statements is true regarding the pH of rectal fluids?
Which of the following statements is true regarding the pH of rectal fluids?
Which of the following dosage forms is most suitable for rectal drug delivery?
Which of the following dosage forms is most suitable for rectal drug delivery?
What is the primary advantage of rectal drug delivery over oral administration?
What is the primary advantage of rectal drug delivery over oral administration?
