Podcast
Questions and Answers
What is the primary goal of recombination mapping?
What is the primary goal of recombination mapping?
What is the unit of measurement for genetic distance?
What is the unit of measurement for genetic distance?
During which process does recombination occur?
During which process does recombination occur?
What is the term for the reassortment of genes/alleles into new combinations?
What is the term for the reassortment of genes/alleles into new combinations?
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What is the result of linkage between genes?
What is the result of linkage between genes?
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What is the term for the closeness of genes on the same chromosome?
What is the term for the closeness of genes on the same chromosome?
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Study Notes
Recombination Mapping
- Recombination mapping is a key strategy for locating genomic regions that affect phenotypes.
- It depends on having many well-characterized marker loci of known genomic locations.
Recombination and Evolution
- Recombination is important to evolution because it brings new combinations of genes together upon which natural selection can act.
- Recombination occurs during gamete production (meiosis) if crossover occurs.
- Recombination is the reassortment of genes/alleles into combinations different from those of the parents as a result of independent assortment.
Linkage
- Linkage refers to the closeness of genes on the same chromosome.
- When genes are linked, they are close by and are inherited together.
- Linkage violates Mendel's rules of independent assortment.
- Parentals always have a higher frequency when there is linkage.
- When there is no linkage, there will be equal frequencies.
- Linkage results in a 1:1 ratio.
Genetic Distance vs. Nucleotide Distance
- Genetic distance is measured in centiMorgans.
- Nucleotide distance is measured in base pairs.
- Genetic distance is not equal to nucleotide distance.
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Description
This quiz covers the concepts of recombination mapping, its importance in evolution, and the distinction between genetic distance and nucleotide distance.
