Recombinant DNA Applications Quiz
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Questions and Answers

What is the nomenclature for a sequence of three nucleotides?

  • Trinucleotide (correct)
  • Oligonucleotide
  • Dinucleotide
  • Mononucleotide
  • Which type of nucleotides are present in oligodeoxyribonucleotides (ODNs)?

  • T A U G
  • U A C G
  • T A C G (correct)
  • C G A T
  • What is the main difference between oligodeoxyribonucleotides and oligoribonucleotides?

  • Function in protein synthesis
  • Structure of the sugar molecule
  • Presence of thymine vs. uracil (correct)
  • Number of nucleotides
  • Which technology is used at the RNA level?

    <p>Antisense technology</p> Signup and view all the answers

    What is the main application of nucleic acid technology for studying diseases and genetic disorders?

    <p>Transgenesis</p> Signup and view all the answers

    What are aptamers used to target at the protein level?

    <p>Enzymes</p> Signup and view all the answers

    What is the function of ribozymes in nucleic acid technology?

    <p>Splicing</p> Signup and view all the answers

    What is the length of oligonucleotides?

    <p>100 or fewer bases long</p> Signup and view all the answers

    What does U replace in oligoribonucleotides?

    <p>T</p> Signup and view all the answers

    What is the main purpose of using microarray in nucleic acid technology?

    <p>Diagnostics</p> Signup and view all the answers

    What does the term 'oligos' refer to?

    <p>A polymer chain</p> Signup and view all the answers

    What is the name given to a 21-base containing oligonucleotide?

    <p>21-mer</p> Signup and view all the answers

    Why are oligodeoxyribonucleotides and oligoribonucleotides highly susceptible to rapid degradation by structurally nonspecific intracellular nucleases?

    <p>They possess a negative charge</p> Signup and view all the answers

    How do natural oligonucleotides accumulate in cells?

    <p>Receptor-mediated endocytosis</p> Signup and view all the answers

    What is the backbone of a peptide nucleic acid (PNA)?

    <p>Aminoethyl glycine units</p> Signup and view all the answers

    What is the technology in which short oligodeoxyribonucleotides can bind sequence-specifically to complementary segments of duplex DNA?

    <p>Triplex Technology</p> Signup and view all the answers

    At which level does antisense oligonucleotide interruption of the flow of genetic information occur?

    <p>mRNA level in the cytoplasm</p> Signup and view all the answers

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